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Erschienen in: HNO 12/2014

01.12.2014 | CME Zertifizierte Fortbildung

Chirurgische Therapie pulmonaler Metastasen von Kopf-Hals-Tumoren

verfasst von: S. Macherey, S.F. Preuss, F. Doerr, S. Grönke, M. Heldwein, A. Quaas, T. Zander, Prof. Dr. K. Hekmat

Erschienen in: HNO | Ausgabe 12/2014

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Zusammenfassung

Die Lungenmetastasenchirurgie ist ein etabliertes Verfahren in onkologischen Therapiekonzepten. Eine systematische Literaturrecherche und Analyse aller Studien, die ab dem 01.01.2000 publiziert worden sind, soll ihren Nutzen für Patienten mit primären Kopf-Hals-Tumoren (KHT) evaluieren. 1,9-13% aller Patienten mit KHT entwickeln Lungenmetastasen. Die Patienten erreichen nach der Metastasektomie 5-Jahres-Überlebensraten bis zu 58 % und ein medianes Überleben zwischen 9,5 und 78 Monaten. Die Raten für intrathorakale Rezidive betragen 18,4–81,8 %. Diese Patienten können sich im Einzelfall einer Remetastasektomie unterziehen. Patienten mit Plattenepithelkarzinomen haben die ungünstigste Prognose, können aber ein Langzeitüberleben (≥ 60 Monate) erreichen. Die Lungenmetastasenchirurgie stellt häufig den einzigen potenziell kurativen Ansatz dar und ermöglicht ein günstigeres Langzeitüberleben als nichtchirurgische Therapieformen. Sie sollte daher die Therapie der ersten Wahl für diese Patienten sein.
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Metadaten
Titel
Chirurgische Therapie pulmonaler Metastasen von Kopf-Hals-Tumoren
verfasst von
S. Macherey
S.F. Preuss
F. Doerr
S. Grönke
M. Heldwein
A. Quaas
T. Zander
Prof. Dr. K. Hekmat
Publikationsdatum
01.12.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
HNO / Ausgabe 12/2014
Print ISSN: 0017-6192
Elektronische ISSN: 1433-0458
DOI
https://doi.org/10.1007/s00106-014-2933-2

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