Skip to main content
Erschienen in: Social Psychiatry and Psychiatric Epidemiology 1/2016

01.01.2016 | Review

Epidemiology and burden of bipolar disorder in Africa: a systematic review of data from Africa

verfasst von: Oluyomi Esan, Arinola Esan

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 1/2016

Einloggen, um Zugang zu erhalten

Abstract

Background

Bipolar disorder impacts negatively on the patient, the family, as well as the society. It taxes the health care services due to a combination of the illness with associated medical and psychiatric comorbidities. In Africa, unfortunately, knowledge of the epidemiology and burden of bipolar disorder is based mainly on studies from the USA and Europe. In this systematic review of literature from Africa, we highlight the epidemiology and burden of bipolar disorder.

Methods

A systematic review of publications from Africa relating to the epidemiology and burden of bipolar disorder was conducted.

Result

Data from community surveys conducted in Nigeria and Ethiopia indicated a lifetime prevalence estimate of 0.1 % to 1.83 for bipolar disorder. Missed diagnosis rate of bipolar disorder was up to 36.2 %. In one study, 8.1 % of the males and 5.4 % of the females reported a previous suicide attempt. A study showed that up to 60 % of patients with bipolar disorder had at least one comorbidity. There were no reports on all-cause mortality and cost of illness.

Conclusion

Bipolar disorder is a major mental health problem in Africa. Scientific findings on bipolar disorder from Africa are consistent with the existing literature from other parts of the world. There still exists a dearth of high quality studies addressing the epidemiological, clinical, social, and economic burden of the disorder.
Literatur
1.
Zurück zum Zitat Whiteford HA, Degenhardt L, Rehm J, Baxter AJ, Ferrari AJ, Erskine HE et al (2013) Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet 382(9904):1575–1586CrossRefPubMed Whiteford HA, Degenhardt L, Rehm J, Baxter AJ, Ferrari AJ, Erskine HE et al (2013) Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010. Lancet 382(9904):1575–1586CrossRefPubMed
2.
Zurück zum Zitat Dore G, Romans SE (2001) Impact of bipolar affective disorder on family and partners. J Affect Disord 67(1–3):147–158CrossRefPubMed Dore G, Romans SE (2001) Impact of bipolar affective disorder on family and partners. J Affect Disord 67(1–3):147–158CrossRefPubMed
3.
Zurück zum Zitat Simon GE (2003) Social and economic burden of mood disorders. Biol Psychiatry 54(3):208–215CrossRefPubMed Simon GE (2003) Social and economic burden of mood disorders. Biol Psychiatry 54(3):208–215CrossRefPubMed
4.
Zurück zum Zitat Huxley N, Baldessarini RJ (2007) Disability and its treatment in bipolar disorder patients. Bipolar Disord 9(1–2):183–196CrossRefPubMed Huxley N, Baldessarini RJ (2007) Disability and its treatment in bipolar disorder patients. Bipolar Disord 9(1–2):183–196CrossRefPubMed
5.
Zurück zum Zitat Pope M, Dudley R, Scott J (2007) Determinants of social functioning in bipolar disorder. Bipolar Disord 9(1–2):38–44CrossRefPubMed Pope M, Dudley R, Scott J (2007) Determinants of social functioning in bipolar disorder. Bipolar Disord 9(1–2):38–44CrossRefPubMed
6.
Zurück zum Zitat Peele PB, Xu Y, Kupfer DJ (2003) Insurance expenditures on bipolar disorder: clinical and parity implications. Am J Psychiatry 160(7):1286–1290CrossRefPubMed Peele PB, Xu Y, Kupfer DJ (2003) Insurance expenditures on bipolar disorder: clinical and parity implications. Am J Psychiatry 160(7):1286–1290CrossRefPubMed
8.
Zurück zum Zitat Laxman KE, Lovibond KS, Hassan MK (2008) Impact of bipolar disorder in employed populations. Am J Manag Care 14(11):757–764PubMed Laxman KE, Lovibond KS, Hassan MK (2008) Impact of bipolar disorder in employed populations. Am J Manag Care 14(11):757–764PubMed
9.
Zurück zum Zitat Kessler RC, Bedirhan Ustun T (2008) The WHO World Mental Health Surveys: global perspectives on the epidemiology of mental disorders. Cambridge University Press, Cambridge Kessler RC, Bedirhan Ustun T (2008) The WHO World Mental Health Surveys: global perspectives on the epidemiology of mental disorders. Cambridge University Press, Cambridge
10.
Zurück zum Zitat Kebede D, Alem A, Shibre T, Negash A, Deyassa N, Beyero T (2005) Socio-demographic correlates of bipolar disorder in Butajira, rural Ethiopia. East Afr Med J 82(1):34–39PubMed Kebede D, Alem A, Shibre T, Negash A, Deyassa N, Beyero T (2005) Socio-demographic correlates of bipolar disorder in Butajira, rural Ethiopia. East Afr Med J 82(1):34–39PubMed
11.
Zurück zum Zitat Negash A, Alem A, Kebede D, Deyessa N, Shibre T, Kullgren G (2005) Prevalence and clinical characteristics of bipolar I disorder in Butajira, Ethiopia: a community-based study. J Affect Disord 87(2–3):193–201CrossRefPubMed Negash A, Alem A, Kebede D, Deyessa N, Shibre T, Kullgren G (2005) Prevalence and clinical characteristics of bipolar I disorder in Butajira, Ethiopia: a community-based study. J Affect Disord 87(2–3):193–201CrossRefPubMed
12.
Zurück zum Zitat Fekadu A, Shibre T, Alem A, Kebede D, Kebreab S, Negash A et al (2004) Bipolar disorder among an isolated island community in Ethiopia. J Affect Disord 80(1):1–10CrossRefPubMed Fekadu A, Shibre T, Alem A, Kebede D, Kebreab S, Negash A et al (2004) Bipolar disorder among an isolated island community in Ethiopia. J Affect Disord 80(1):1–10CrossRefPubMed
13.
Zurück zum Zitat Gureje O, Adeyemi O, Enyidah N, Ekpo M, Udofia O, Uwakwe R et al (2008) Mental disorders among adult nigerians: risks, prevalence, and treatment. In: Kessler C, Bedirhan Ustun T (eds) The WHO World Mental Health Surveys: global perspectives on the epidemiology of mental disorders. Cambridge University Press, pp 211–237 Gureje O, Adeyemi O, Enyidah N, Ekpo M, Udofia O, Uwakwe R et al (2008) Mental disorders among adult nigerians: risks, prevalence, and treatment. In: Kessler C, Bedirhan Ustun T (eds) The WHO World Mental Health Surveys: global perspectives on the epidemiology of mental disorders. Cambridge University Press, pp 211–237
14.
Zurück zum Zitat Kebede D, Alem A (1999) Major mental disorders in Addis Ababa, Ethiopia. II. Affective disorders. Acta Psychiatr Scand Suppl 397:18–23CrossRefPubMed Kebede D, Alem A (1999) Major mental disorders in Addis Ababa, Ethiopia. II. Affective disorders. Acta Psychiatr Scand Suppl 397:18–23CrossRefPubMed
15.
Zurück zum Zitat Ndetei DM, Khasakhala L, Maru H, Pizzo M, Mutiso V, Ongecha-Owuor FA et al (2008) Clinical epidemiology in patients admitted at Mathari Psychiatric Hospital, Nairobi, Kenya. Social Psychiatry Psychiatric Epidemiol 43(9):736–742CrossRef Ndetei DM, Khasakhala L, Maru H, Pizzo M, Mutiso V, Ongecha-Owuor FA et al (2008) Clinical epidemiology in patients admitted at Mathari Psychiatric Hospital, Nairobi, Kenya. Social Psychiatry Psychiatric Epidemiol 43(9):736–742CrossRef
16.
Zurück zum Zitat Atwoli L, Ndambuki D, Owiti P, Manguro G, Omulimi N (2012) Short-term diagnostic stability among re-admitted psychiatric in-patients in Eldoret, Kenya. Afr J Psychiatry 15(2):114–118 Atwoli L, Ndambuki D, Owiti P, Manguro G, Omulimi N (2012) Short-term diagnostic stability among re-admitted psychiatric in-patients in Eldoret, Kenya. Afr J Psychiatry 15(2):114–118
17.
Zurück zum Zitat Naidoo S, Mkize DL (2012) Prevalence of mental disorders in a prison population in Durban, South Africa. Afr J Psychiatry 15(1):30–35CrossRef Naidoo S, Mkize DL (2012) Prevalence of mental disorders in a prison population in Durban, South Africa. Afr J Psychiatry 15(1):30–35CrossRef
18.
Zurück zum Zitat Uys H (2013) Prevalence and clinical presentation of HIV positive female psychiatric inpatients. Afr J Psychiatry 16(1):23–28 Uys H (2013) Prevalence and clinical presentation of HIV positive female psychiatric inpatients. Afr J Psychiatry 16(1):23–28
19.
Zurück zum Zitat Okasha T, Fikry M, Kowailed A, El-Guwiely T, Sadek H (2013) Screening for bipolar disorder among patients undergoing a major depressive episode: report from the BRIDGE study in Egypt. J Affect Disord 147(1–3):217–224CrossRefPubMed Okasha T, Fikry M, Kowailed A, El-Guwiely T, Sadek H (2013) Screening for bipolar disorder among patients undergoing a major depressive episode: report from the BRIDGE study in Egypt. J Affect Disord 147(1–3):217–224CrossRefPubMed
20.
Zurück zum Zitat Adegbaju DA, Olagunju AT, Uwakwe R (2013) A comparative analysis of disability in individuals with bipolar affective disorder and schizophrenia in a sub-Saharan African mental health hospital: towards evidence-guided rehabilitation intervention. Soc Psychiatry Psychiatr Epidemiol 48(9):1405–1415CrossRefPubMed Adegbaju DA, Olagunju AT, Uwakwe R (2013) A comparative analysis of disability in individuals with bipolar affective disorder and schizophrenia in a sub-Saharan African mental health hospital: towards evidence-guided rehabilitation intervention. Soc Psychiatry Psychiatr Epidemiol 48(9):1405–1415CrossRefPubMed
21.
Zurück zum Zitat Bakare MO, Agomoh AO, Eaton J, Ebigbo PO, Onwukwe JU (2011) Functional status and its associated factors in Nigerian adolescents with bipolar disorder. Afr J Psychiatry 14(5):388–391CrossRef Bakare MO, Agomoh AO, Eaton J, Ebigbo PO, Onwukwe JU (2011) Functional status and its associated factors in Nigerian adolescents with bipolar disorder. Afr J Psychiatry 14(5):388–391CrossRef
22.
Zurück zum Zitat Onyeama M, Agomoh A, Jombo E (2010) Bipolar disorder in Enugu, South East Nigeria: demographic and diagnostic characteristics of patients. Psychiatria Danubina 22(Suppl 1):S152–S157PubMed Onyeama M, Agomoh A, Jombo E (2010) Bipolar disorder in Enugu, South East Nigeria: demographic and diagnostic characteristics of patients. Psychiatria Danubina 22(Suppl 1):S152–S157PubMed
23.
Zurück zum Zitat Gassab L, Mechri A, Gaha L, Khiari G, Zaafrane F, Zougaghi L (2002) Bipolarity correlated factors in major depression: about 155 Tunisian inpatients. L'Encephale 28(4):283–289PubMed Gassab L, Mechri A, Gaha L, Khiari G, Zaafrane F, Zougaghi L (2002) Bipolarity correlated factors in major depression: about 155 Tunisian inpatients. L'Encephale 28(4):283–289PubMed
24.
Zurück zum Zitat Fekadu A, Kebede D, Alem A, Fekadu D, Mogga S, Negash A et al (2006) Clinical outcome in bipolar disorder in a community-based follow-up study in Butajira, Ethiopia. Acta Psychiatr Scand 114(6):426–434CrossRefPubMed Fekadu A, Kebede D, Alem A, Fekadu D, Mogga S, Negash A et al (2006) Clinical outcome in bipolar disorder in a community-based follow-up study in Butajira, Ethiopia. Acta Psychiatr Scand 114(6):426–434CrossRefPubMed
25.
Zurück zum Zitat Ezzaher A, Haj Mouhamed D, Mechri A, Neffati F, Douki W, Gaha L et al (2010) Obesity and dyslipidemia in Tunisian bipolar subjects. Ann Biol Clin 68(3):277–284 Ezzaher A, Haj Mouhamed D, Mechri A, Neffati F, Douki W, Gaha L et al (2010) Obesity and dyslipidemia in Tunisian bipolar subjects. Ann Biol Clin 68(3):277–284
26.
Zurück zum Zitat Ezzaher A, Haj MD, Mechri A, Neffati F, Douki W, Gaha L et al (2011) Metabolic syndrome in Tunisian bipolar I patients. Afr Health Sci 11(3):414–420PubMedCentralPubMed Ezzaher A, Haj MD, Mechri A, Neffati F, Douki W, Gaha L et al (2011) Metabolic syndrome in Tunisian bipolar I patients. Afr Health Sci 11(3):414–420PubMedCentralPubMed
27.
Zurück zum Zitat Kebede D, Alem A, Shibire T, Deyassa N, Negash A, Beyero T et al (2006) Symptomatic and functional outcome of bipolar disorder in Butajira, Ethiopia. J Affect Disord 90(2–3):239–249CrossRefPubMed Kebede D, Alem A, Shibire T, Deyassa N, Negash A, Beyero T et al (2006) Symptomatic and functional outcome of bipolar disorder in Butajira, Ethiopia. J Affect Disord 90(2–3):239–249CrossRefPubMed
28.
Zurück zum Zitat Merikangas KR, Jin R, He JP, Kessler RC, Lee S, Sampson NA et al (2011) Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Arch Gen Psychiatry 68(3):241–251PubMedCentralCrossRefPubMed Merikangas KR, Jin R, He JP, Kessler RC, Lee S, Sampson NA et al (2011) Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Arch Gen Psychiatry 68(3):241–251PubMedCentralCrossRefPubMed
29.
Zurück zum Zitat Merikangas KR, Akiskal HS, Angst J, Greenberg PE, Hirschfeld RM, Petukhova M et al (2007) Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Arch Gen Psychiatry 64(5):543–552PubMedCentralCrossRefPubMed Merikangas KR, Akiskal HS, Angst J, Greenberg PE, Hirschfeld RM, Petukhova M et al (2007) Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication. Arch Gen Psychiatry 64(5):543–552PubMedCentralCrossRefPubMed
30.
Zurück zum Zitat Shibre T, Kebede D, Alem A, Negash A, Kibreab S, Fekadu A et al (2002) An evaluation of two screening methods to identify cases with schizophrenia and affective disorders in a community survey in rural Ethiopia. Int J Soc Psychiatry 48(3):200–208CrossRefPubMed Shibre T, Kebede D, Alem A, Negash A, Kibreab S, Fekadu A et al (2002) An evaluation of two screening methods to identify cases with schizophrenia and affective disorders in a community survey in rural Ethiopia. Int J Soc Psychiatry 48(3):200–208CrossRefPubMed
31.
Zurück zum Zitat American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Publishing American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Publishing
32.
Zurück zum Zitat Faravelli C, Guerrini Degl'Innocenti B, Aiazzi L, Incerpi G, Pallanti S (1990) Epidemiology of mood disorders: a community survey in Florence. J Affect Disord 20(2):135–141CrossRefPubMed Faravelli C, Guerrini Degl'Innocenti B, Aiazzi L, Incerpi G, Pallanti S (1990) Epidemiology of mood disorders: a community survey in Florence. J Affect Disord 20(2):135–141CrossRefPubMed
34.
Zurück zum Zitat Sanchez-Moreno J, Martinez-Aran A, Tabares-Seisdedos R, Torrent C, Vieta E, Ayuso-Mateos JL (2009) Functioning and disability in bipolar disorder: an extensive review. Psychother Psychosom 78(5):285–297CrossRefPubMed Sanchez-Moreno J, Martinez-Aran A, Tabares-Seisdedos R, Torrent C, Vieta E, Ayuso-Mateos JL (2009) Functioning and disability in bipolar disorder: an extensive review. Psychother Psychosom 78(5):285–297CrossRefPubMed
35.
Zurück zum Zitat Manove E, Levy B (2010) Cognitive impairment in bipolar disorder: an overview. Postgrad Med 122(4):7–16CrossRefPubMed Manove E, Levy B (2010) Cognitive impairment in bipolar disorder: an overview. Postgrad Med 122(4):7–16CrossRefPubMed
36.
37.
Zurück zum Zitat Passarotti AM, Sweeney JA, Pavuluri MN (2010) Differential engagement of cognitive and affective neural systems in pediatric bipolar disorder and attention deficit hyperactivity disorder. JINS 16(1):106–117PubMedCentralPubMed Passarotti AM, Sweeney JA, Pavuluri MN (2010) Differential engagement of cognitive and affective neural systems in pediatric bipolar disorder and attention deficit hyperactivity disorder. JINS 16(1):106–117PubMedCentralPubMed
38.
Zurück zum Zitat Rock PL, Goodwin GM, Harmer CJ (2010) The common adolescent bipolar phenotype shows positive biases in emotional processing. Bipolar Disord 12(6):606–615CrossRefPubMed Rock PL, Goodwin GM, Harmer CJ (2010) The common adolescent bipolar phenotype shows positive biases in emotional processing. Bipolar Disord 12(6):606–615CrossRefPubMed
39.
Zurück zum Zitat Cannon M, Jones P, Gilvarry C, Rifkin L, McKenzie K, Foerster A et al (1997) Premorbid social functioning in schizophrenia and bipolar disorder: similarities and differences. Am J Psychiatry 154(11):1544–1550PubMed Cannon M, Jones P, Gilvarry C, Rifkin L, McKenzie K, Foerster A et al (1997) Premorbid social functioning in schizophrenia and bipolar disorder: similarities and differences. Am J Psychiatry 154(11):1544–1550PubMed
40.
Zurück zum Zitat Judd LL, Schettler PJ, Solomon DA, Maser JD, Coryell W, Endicott J et al (2008) Psychosocial disability and work role function compared across the long-term course of bipolar I, bipolar II and unipolar major depressive disorders. J Affect Disord 108(1–2):49–58CrossRefPubMed Judd LL, Schettler PJ, Solomon DA, Maser JD, Coryell W, Endicott J et al (2008) Psychosocial disability and work role function compared across the long-term course of bipolar I, bipolar II and unipolar major depressive disorders. J Affect Disord 108(1–2):49–58CrossRefPubMed
41.
Zurück zum Zitat Judd LL, Akiskal HS, Schettler PJ, Endicott J, Leon AC, Solomon DA et al (2005) Psychosocial disability in the course of bipolar I and II disorders: a prospective, comparative, longitudinal study. Arch Gen Psychiatry 62(12):1322–1330CrossRefPubMed Judd LL, Akiskal HS, Schettler PJ, Endicott J, Leon AC, Solomon DA et al (2005) Psychosocial disability in the course of bipolar I and II disorders: a prospective, comparative, longitudinal study. Arch Gen Psychiatry 62(12):1322–1330CrossRefPubMed
42.
Zurück zum Zitat Grande I, Goikolea JM, de Dios C, Gonzalez-Pinto A, Montes JM, Saiz-Ruiz J et al (2013) Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit (PREBIS study data). Acta Psychiatr Scand 127(5):403–411CrossRefPubMed Grande I, Goikolea JM, de Dios C, Gonzalez-Pinto A, Montes JM, Saiz-Ruiz J et al (2013) Occupational disability in bipolar disorder: analysis of predictors of being on severe disablement benefit (PREBIS study data). Acta Psychiatr Scand 127(5):403–411CrossRefPubMed
43.
Zurück zum Zitat Mortensen PB, Pedersen CB, Melbye M, Mors O, Ewald H (2003) Individual and familial risk factors for bipolar affective disorders in Denmark. Arch Gen Psychiatry 60(12):1209–1215CrossRefPubMed Mortensen PB, Pedersen CB, Melbye M, Mors O, Ewald H (2003) Individual and familial risk factors for bipolar affective disorders in Denmark. Arch Gen Psychiatry 60(12):1209–1215CrossRefPubMed
44.
Zurück zum Zitat Tsuchiya KJ, Byrne M, Mortensen PB (2003) Risk factors in relation to an emergence of bipolar disorder: a systematic review. Bipolar Disord 5(4):231–242CrossRefPubMed Tsuchiya KJ, Byrne M, Mortensen PB (2003) Risk factors in relation to an emergence of bipolar disorder: a systematic review. Bipolar Disord 5(4):231–242CrossRefPubMed
45.
Zurück zum Zitat Weissman MM, Leaf PJ, Tischler GL, Blazer DG, Karno M, Bruce ML et al (1988) Affective disorders in five United States communities. Psychol Med 18(1):141–153CrossRefPubMed Weissman MM, Leaf PJ, Tischler GL, Blazer DG, Karno M, Bruce ML et al (1988) Affective disorders in five United States communities. Psychol Med 18(1):141–153CrossRefPubMed
46.
Zurück zum Zitat Lloyd T, Kennedy N, Fearon P, Kirkbride J, Mallett R, Leff J et al (2005) Incidence of bipolar affective disorder in three UK cities: results from the AESOP study. Br J Psychiatry 186:126–131CrossRefPubMed Lloyd T, Kennedy N, Fearon P, Kirkbride J, Mallett R, Leff J et al (2005) Incidence of bipolar affective disorder in three UK cities: results from the AESOP study. Br J Psychiatry 186:126–131CrossRefPubMed
47.
Zurück zum Zitat Weissman MM, Bland RC, Canino GJ, Faravelli C, Greenwald S, Hwu HG et al (1996) Cross-national epidemiology of major depression and bipolar disorder. JAMA 276(4):293–299CrossRefPubMed Weissman MM, Bland RC, Canino GJ, Faravelli C, Greenwald S, Hwu HG et al (1996) Cross-national epidemiology of major depression and bipolar disorder. JAMA 276(4):293–299CrossRefPubMed
48.
Zurück zum Zitat Suominen K, Mantere O, Valtonen H, Arvilommi P, Leppamaki S, Paunio T et al (2007) Early age at onset of bipolar disorder is associated with more severe clinical features but delayed treatment seeking. Bipolar Disord 9(7):698–705CrossRefPubMed Suominen K, Mantere O, Valtonen H, Arvilommi P, Leppamaki S, Paunio T et al (2007) Early age at onset of bipolar disorder is associated with more severe clinical features but delayed treatment seeking. Bipolar Disord 9(7):698–705CrossRefPubMed
49.
Zurück zum Zitat Perlis RH, Dennehy EB, Miklowitz DJ, Delbello MP, Ostacher M, Calabrese JR et al (2009) Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study. Bipolar Disord 11(4):391–400PubMedCentralCrossRefPubMed Perlis RH, Dennehy EB, Miklowitz DJ, Delbello MP, Ostacher M, Calabrese JR et al (2009) Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study. Bipolar Disord 11(4):391–400PubMedCentralCrossRefPubMed
50.
Zurück zum Zitat Weissman MM, Kidd KK, Prusoff BA (1982) Variability in rates of affective disorders in relatives of depressed and normal probands. Arch Gen Psychiatry 39(12):1397–1403CrossRefPubMed Weissman MM, Kidd KK, Prusoff BA (1982) Variability in rates of affective disorders in relatives of depressed and normal probands. Arch Gen Psychiatry 39(12):1397–1403CrossRefPubMed
51.
Zurück zum Zitat Kebede D, Alem A, Deyassa N, Shibre T, Negash A, Beyero T (2003) Socio-demographic correlates of depressive disorder in Butajira, rural Ethiopia. Cent Afr J Med 49(7–8):78–83PubMed Kebede D, Alem A, Deyassa N, Shibre T, Negash A, Beyero T (2003) Socio-demographic correlates of depressive disorder in Butajira, rural Ethiopia. Cent Afr J Med 49(7–8):78–83PubMed
52.
Zurück zum Zitat Carney CP, Jones LE (2006) Medical comorbidity in women and men with bipolar disorders: a population-based controlled study. Psychosom Med 68(5):684–691CrossRefPubMed Carney CP, Jones LE (2006) Medical comorbidity in women and men with bipolar disorders: a population-based controlled study. Psychosom Med 68(5):684–691CrossRefPubMed
53.
54.
Zurück zum Zitat McElroy SL, Altshuler LL, Suppes T, Keck PE Jr, Frye MA, Denicoff KD et al (2001) Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. Am J Psychiatry 158(3):420–426CrossRefPubMed McElroy SL, Altshuler LL, Suppes T, Keck PE Jr, Frye MA, Denicoff KD et al (2001) Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. Am J Psychiatry 158(3):420–426CrossRefPubMed
55.
Zurück zum Zitat Fajutrao L, Locklear J, Priaulx J, Heyes A (2009) A systematic review of the evidence of the burden of bipolar disorder in Europe. Clin Pract Epidemiol Ment Health 5:3 Fajutrao L, Locklear J, Priaulx J, Heyes A (2009) A systematic review of the evidence of the burden of bipolar disorder in Europe. Clin Pract Epidemiol Ment Health 5:3
56.
Zurück zum Zitat Latalova K, Kamaradova D, Prasko J (2014) Suicide in bipolar disorder: a review. Psychiatr Danubina 26(2):108–114 Latalova K, Kamaradova D, Prasko J (2014) Suicide in bipolar disorder: a review. Psychiatr Danubina 26(2):108–114
57.
Zurück zum Zitat Pompili M, Gonda X, Serafini G, Innamorati M, Sher L, Amore M et al (2013) Epidemiology of suicide in bipolar disorders: a systematic review of the literature. Bipolar Disord 15(5):457–490CrossRefPubMed Pompili M, Gonda X, Serafini G, Innamorati M, Sher L, Amore M et al (2013) Epidemiology of suicide in bipolar disorders: a systematic review of the literature. Bipolar Disord 15(5):457–490CrossRefPubMed
58.
Zurück zum Zitat Goldberg JF, Harrow M, Grossman LS (1995) Course and outcome in bipolar affective disorder: a longitudinal follow-up study. Am J Psychiatry 152(3):379–384CrossRefPubMed Goldberg JF, Harrow M, Grossman LS (1995) Course and outcome in bipolar affective disorder: a longitudinal follow-up study. Am J Psychiatry 152(3):379–384CrossRefPubMed
59.
Zurück zum Zitat MacQueen GM, Young LT, Joffe RT (2001) A review of psychosocial outcome in patients with bipolar disorder. Acta Psychiatr Scand 103(3):163–170CrossRefPubMed MacQueen GM, Young LT, Joffe RT (2001) A review of psychosocial outcome in patients with bipolar disorder. Acta Psychiatr Scand 103(3):163–170CrossRefPubMed
60.
Zurück zum Zitat Marwaha S, Durrani A, Singh S (2013) Employment outcomes in people with bipolar disorder: a systematic review. Acta Psychiatr Scand 128(3):179–193CrossRefPubMed Marwaha S, Durrani A, Singh S (2013) Employment outcomes in people with bipolar disorder: a systematic review. Acta Psychiatr Scand 128(3):179–193CrossRefPubMed
Metadaten
Titel
Epidemiology and burden of bipolar disorder in Africa: a systematic review of data from Africa
verfasst von
Oluyomi Esan
Arinola Esan
Publikationsdatum
01.01.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Social Psychiatry and Psychiatric Epidemiology / Ausgabe 1/2016
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-015-1091-5

Weitere Artikel der Ausgabe 1/2016

Social Psychiatry and Psychiatric Epidemiology 1/2016 Zur Ausgabe

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.