Background
Objectives
Hypotheses (for quantitative data analyses)
Qualitative study aims
Qualitative study questions
Methods
Design
Quantitative research methodology
Overview of data from primary care
Setting
Demographic indicators
Severe mental illnesses
Cardiovascular disease indicators
Psychotropic medications
Overview of data from secondary care
South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Case Register
Measures from secondary care
Demographic indicators
Psychotropic medications
Mental disorder
Cause-specific mortality
Development of a measure for individual-level socioeconomic position
Analyses
Sample size calculation
Primary care data source |
N
| Prevalence of outcome in white British group | ||
---|---|---|---|---|
White British | 238,211 | 10 % | 20 % | 50 % |
Smallest detectable odds ratio | ||||
Bangladeshi | 93,143 | 1.03 | 1.02 | 1.01 |
Irish | 13,459 | 1.08 | 1.05 | 1.03 |
Secondary care data source |
N
| Prevalence of outcome in white British group | ||
---|---|---|---|---|
white British | 28,618 | 10 % | 20 % | 50 % |
Smallest detectable odds ratio | ||||
‘Other’ white | 4477 | 1.14 | 1.09 | 1.05 |
Indian | 711 | 1.35 | 1.23 | 1.11 |
Qualitative study
Methodology
Sampling frame for qualitative research
Topic guide for qualitative study
Analysis of qualitative data and integration with quantitative findings
Ethical standards
Results
Primary care
Lambeth | Tower Hamlets | Newham | City and Hackney | |
---|---|---|---|---|
Participants N (%) | 295,516 (30) | 214,600 (21.6) | 282,512 (28.4) | 200,488 (20.2) |
Practices N (%) | 47 (25) | 37 (20) | 64 (34) | 41 (22) |
Proportion resident in most deprived areasa
N (%) | 254,593 (86.2) | 169,036 (90.0) | 263,681 (98.8) | 176,463 (97.7) |
Proportion ethnic minorities N (%) | 152,307 (62.1) | 133,727 (68.2) | 220,549 (84.0) | 118,637 (66.9) |
Prevalence severe mental illness | ||||
N
| 4718 | 3477 | 3706 | 3484 |
% (95 % CI) | 1.60 (1.55, 1.64) | 1.62 (1.57, 1.67) | 1.31 (1.27, 1.35) | 1.74 (1.68, 1.80) |
Prevalence type 2 diabetes | ||||
N
| 13,372 | 13,479 | 20,309 | 10,754 |
% (95 % CI) | 4.54 (4.47, 4.62) | 6.30 (6.20, 6.40) | 7.20 (7.11, 7.30) | 5.38 (5.28, 5.48) |
Prevalence hypertension | ||||
N
| 32,454 | 22,238 | 38,632 | 24,993 |
% (95 % CI) | 10.98 (10.87, 11.10) | 10.36 (10.23, 10.49) | 13.67 (13.55, 13.80) | 12.47 (12.32, 12.61) |
Prevalence ischaemic heart disease | ||||
N
| 5103 | 4792 | 6759 | 4226 |
% (95 % CI) | 1.73 (1.68, 1.77) | 2.23 (2.17, 2.30) | 2.39 (2.34, 2.45) | 2.11 (2.05, 2.17) |
Current or ex-smoker | ||||
N
| 132,741 | 48,266 | 47,749 | 46,412 |
% (95 % CI) | 46.62 (46.44, 46.80) | 50.40 (50.08, 50.72) | 40.31 (40.02, 40.59) | 50.33 (50.00, 50.65) |
Not on SMI registera
N = 997,731 | Severe mental illness (SMI register)a
N = 15,385 | Total | |||
---|---|---|---|---|---|
N
| % |
N
| % |
N
| |
Age (mean, SD) | 40 (15.5) | 47 (15.3) | 993,116 | ||
Sex | |||||
Men | 494,304 | 51 | 8488 | 55 | 502,792 |
Women | 483,426 | 49 | 6897 | 45 | 490,323 |
Ethnicity | |||||
White British | 238,211 | 27 | 4403 | 31 | 242,614 |
Irish | 13,459 | 2 | 286 | 2 | 13,745 |
‘Other’ white | 171,493 | 20 | 1442 | 10 | 172,935 |
Indian | 60,298 | 7 | 566 | 4 | 60,864 |
Pakistani | 35,215 | 4 | 381 | 3 | 35,596 |
Bangladeshi | 93,143 | 11 | 1500 | 10 | 94,643 |
Black Caribbean | 43,367 | 5 | 1646 | 11 | 45,013 |
Black African | 74,037 | 9 | 1417 | 10 | 75,454 |
‘Other’/Chinese | 110,094 | 13 | 2027 | 14 | 112,121 |
Mixed ethnicity | 27,877 | 3 | 717 | 5 | 28,594 |
Area-level deprivation (quintiles) | |||||
1 Most deprived | 587,820 | 64 | 10,437 | 71 | 589,257 |
2 | 261,966 | 29 | 3550 | 24 | 265,516 |
3 | 51,207 | 6 | 521 | 4 | 51,728 |
4 | 10,396 | 1.1 | 96 | 0.7 | 10,492 |
5 Least deprived | 4626 | 0.5 | 21 | 0.1 | 4647 |
Secondary care
Schizophrenia | Schizoaffective disorder | Bipolar affective disorder | |
---|---|---|---|
N = 6885 |
N = 1438 |
N = 4112 | |
Ethnicity, n (%) | |||
White British | 2271 (33) | 519 (36) | 2033 (49) |
‘Other’ white | 473 (7) | 93 (6) | 376 (9) |
Irish | 141 (2) | 37(3) | 132 (3) |
Indian | 131 (2) | 21 (1) | 64 (2) |
Pakistani | 55 (0.1) | 10 (0.7) | 24 (0.6) |
Bangladeshi | 29 (0.4) | 8 (0.6) | 18 (0.4) |
Black Caribbean | 1004 (15) | 173 (12) | 255 (6) |
Black African | 926 (13) | 194 (13) | 273 (7) |
‘Other’/Chinese | 1472 (21) | 284 (20) | 606 (15) |
Mixed ethnicity | 97 (1) | 22 (1.5) | 48 (1) |
Not stated/missing | 286 (4) | 71 (4.9) | 257 (6) |