Erschienen in:
01.07.2015 | Journal club
Improving survival in amyotrophic lateral sclerosis: future treatments in a modern service
verfasst von:
James Hrastelj, Neil P. Robertson
Erschienen in:
Journal of Neurology
|
Ausgabe 7/2015
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Excerpt
Efforts to improve survival in amyotrophic lateral sclerosis (ALS) to date have yielded only modest results, leading to an historically nihilistic approach to management. In the meantime, genetic advances continue to provide new pathways for therapeutic opportunity and the ALS gene discovery curve is exponential. Indeed, the first paper discussed this month confirms the discovery of another new gene associated with ALS and provides further novel insights into the pathogenic mechanism. …