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Erschienen in: Der Diabetologe 6/2015

01.09.2015 | CME

Insuline und Hypoglykämie

Forensische Betrachtung

verfasst von: Dr. C. Heß, B. Madea

Erschienen in: Die Diabetologie | Ausgabe 6/2015

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Zusammenfassung

Diabetes mellitus ist eine weltweit auftretende chronische Erkrankung. Von ausgeprägtem klinischen und auch forensischen Interesse ist die Entwicklung einer Hypoglykämie, die sowohl spontan als auch infolge der Applikation von Insulin/Insulinanaloga bzw. oraler Antidiabetika auftreten kann. Hypoglykämien besitzen erhebliche verkehrsmedizinische Relevanz. Besonders bedeutsam ist die Hypoglykämiewahrnehmungsstörung, die bei 25 % aller Menschen mit Typ-1-Diabetes beobachtet wird. Diagnostik und Beurteilung einer Hypoglykämie im Straßenverkehr basieren auf Anamnese, Auswertung der Therapie im konkreten Fall und Laboranalysen, die häufig zu spät durchgeführt werden. Die vorsätzliche Herbeiführung einer Hypoglykämie in suizidaler bzw. homizidaler Absicht stellt die Analytik vor erhebliche Herausforderungen. Die Diagnose der Hypoglykämie sollte durch eine Analyse der Glaskörperflüssigkeit (Summenwert nach Traub) erfolgen. Für den Nachweis extern beigebrachten Insulins ist die massenspektrometrische Analyse von Insulin und C-Peptid an Serum, Glaskörperflüssigkeit und einer verdächtigen Einstichstelle unabdingbar.
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Metadaten
Titel
Insuline und Hypoglykämie
Forensische Betrachtung
verfasst von
Dr. C. Heß
B. Madea
Publikationsdatum
01.09.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Die Diabetologie / Ausgabe 6/2015
Print ISSN: 2731-7447
Elektronische ISSN: 2731-7455
DOI
https://doi.org/10.1007/s11428-015-0009-x

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