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Exp Clin Endocrinol Diabetes 2015; 123(04): 246-251
DOI: 10.1055/s-0034-1395634
Article
© Georg Thieme Verlag KG Stuttgart · New York

Evaluation of Cognitive Functions in Gestational Diabetes Mellitus

F. E. Keskin
1   Division of Endocrinology-Metabolism and Diabetes, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
,
M. Ozyazar
1   Division of Endocrinology-Metabolism and Diabetes, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
,
A. S. Pala
1   Division of Endocrinology-Metabolism and Diabetes, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
,
A. D. Elmali
2   Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
,
B. Yilmaz
2   Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
,
U. Uygunoglu
2   Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
,
M. Bozluolcay
2   Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
,
A. Tuten
3   Department of Gynecology and Obstetrics, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
,
A. Bingöl
4   Mayis Psychology Center, Istanbul, Turkey
,
E. Hatipoglu
1   Division of Endocrinology-Metabolism and Diabetes, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
› Author Affiliations
Further Information

Publication History

received 13 August 2014
first decision 09 November 2014

accepted 12 November 2014

Publication Date:
13 April 2015 (online)

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Abstract

Objective: To evaluate the association between cognitive functions and metabolic status in cases with gestational diabetes mellitus (GDM).

Methods: In this study 44 patients with GDM and 45 normal pregnant were included. Depression was evaluated with Beck’s depression inventory (BDI). Cognitive functions were evaluated with Montreal cognitive assessment (MOCA), paced auditory serial addition test (PASAT), spatial recall test (SRT), symbol digit modalities (SDMT), and word list generation (WLG).

Results: The mean gestational age, educational level and account of previous birth of the subjects in the study were not statistically different between the groups. The mean scores of BDI of the 2 groups were not statistically different. MOCA score and SDMT was significantly decreased in GDM in comparison to NP (p=0.005, p=0.04 respectively). Also, SDMT score was inversely correlated with number of pregnancies, postprandial blood glucose and HbA1c.The scores of PASAT, SRT, SPART and WLG were statistically similar between the groups.

Conclusions: Our findings may be a clue for early onset of impairment in cognitive functions in cases with new onset diabetes during pregnancy.

Key words

gestational diabetes - cognitive functions - pregnancy
 

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