Einflussfaktoren auf die Ergebnisse des Farbpigmentprobentests Roth 28-hue (E) desaturiert bei Glaukompatienten

 

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Zusammenfassung

Hintergrund: Das Glaukom ist eine Augenerkrankung, bei der es zu einer progredienten Schädigung des Sehnervs nach krankheitstypischem Muster kommt. In der Vergangenheit wurde postuliert, dass es durch das Glaukom zu erworbenen Farbsinnstörungen kommt. Bei allen bisher durchgeführten Untersuchungen zum Glaukom und zu Farbsinnstörungen wurden jedoch die vaskulären Begleiterkrankungen nicht explizit berücksichtigt. Deshalb war es Ziel dieser Untersuchung, die verschiedenen internistischen Einflussfaktoren auf die Ergebnisse im Farbpigmentprobentest Roth 28-hue (E) desaturiert bei Glaukompatienten zu untersuchen.

Patienten und Methoden: 353 Glaukompatienten wurden retrospektiv ausgewertet. Mithilfe einer Varianzanalyse wurde der Einfluss verschiedener Gefäßerkrankungen auf die Ergebnisse im Farbpigmentprobentest Roth 28-hue (E) desaturiert bei Glaukompatienten untersucht.

Ergebnisse: Es zeigte sich ein deutlicher Einfluss von Alter und mittlerem Gesichtsfelddefekt, sowie unabhängig davon ein Effekt von arteriosklerotischen und vasospastischen Gefäßerkrankungen auf die Ergebnisse im Farbpigmentprobentest Roth 28-hue (E) desaturiert.

Schlussfolgerung: Die Ergebnisse lassen vermuten, dass arteriosklerotische und vasospastische Gefäßerkrankungen unabhängig vom Glaukom einen Einfluss auf das Farbensehen haben. Zukünftig müssen bei Farbsinntests bei Glaukompatienten auch die vaskulären Risikofaktoren berücksichtigt werden.

Abstract

Background: Glaucoma is an ocular disease with typical progressive damage of the optic nerve. In the past it was postulated that glaucoma induces acquired colour vision disorders. Until now all studies about glaucoma and colour vision disorders did not include vascular risk factors. In the present study we determined several vascular risk factors concerning the results of the colour vision test Roth 28-hue (E) desaturated in glaucoma patients.

Patients and Methods: On the basis of an analysis of variance (ANOVA) we determined the influence of several risk factors, such as arteriosclerotic and vasospastic risk factors, on the results of the colour vision test Roth 28-hue (E) desaturated in glaucoma patients. 353 glaucoma patients were included in this study.

Results: We detected a strong influence of age and mean defect in perimetry and an additional effect of arteriosclerotic and vasospastic risk factors on the results of the colour vision test Roth 28-hue (E) desaturated in glaucoma patients.

Conclusions: We suspect that arteriosclerotic and vasospastic risk factors independently to glaucoma have an influence on colour vision. In the future attention additionally has to be given to vascular risk factors in the colour vision testing of glaucoma patients.

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