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01.02.2015 | e-Herz: Case study

ST elevation myocardial infarction after use of pseudoephedrine

Which is more dangerous, the common cold itself or the medication used for it?

verfasst von: S. Fidan, M.D., S. Izci, M. Tellice, E. Alizade, G. Açar

Erschienen in: Herz | Ausgabe 1/2015

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Excerpt

The common cold is an infectious disease of upper respiratory tract, usually due to viruses. Although there are some preliminary data showing the benefit of antiviral drugs, we do not have effective drugs for treatment of common cold beyond symptom relief. The common cold is a self-limiting disease with symptoms that generally improve within a week. However, drugs that help to alleviate symptoms (e.g., antipyretics, analgesics, vitamin C) are usually prescribed by physicians. In addition, pseudoephedrine-containing drugs are widely used as a decongestant in many cases because of its sympathomimetic activity [1]. We would like to share a patient who presented with acute ST elevation myocardial infarction after pseudoephedrine use. …

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Berlin I, Warot D, Aymard G et al (2001) Pharmacodynamics and pharmacokinetics of single nasal (5 mg and 10 mg) and oral (50 mg) doses of ephedrine in healthy subjects. Eur J Clin Pharmacol 57:447–455CrossRefPubMed

Persky AM, Berry NS, Pollack GM et al (2004) Modelling the cardiovascular effects of ephedrine. Br J Clin Pharmacol 57(5):552–562 (PMCID: PMC1884497)

Cantu C, Arauz A, Murillo-Bonilla LM et al (2003) Stroke associated with sympathomimetics contained in over-the-counter cough and cold drugs. Stroke 34(7):1667–1672CrossRefPubMed

Biyik I, Ergene O (2006) Myocardial infarction associated with pseudoephedrine use and acute streptococcal infection in a boy with normal coronary arteries. Can J Cardiol 22(3):254–256CrossRefPubMedCentralPubMed

Wiener I, Tilkian AG, Palazzolo M (1990) Coronary artery spasm and myocardial infarction in a patient with normal coronary arteries: temporal relationship to pseudoephedrine ingestion. Cathet Cardiovasc Diagn 20:51–53CrossRefPubMed

Titel: ST elevation myocardial infarction after use of pseudoephedrine
Which is more dangerous, the common cold itself or the medication used for it?
verfasst von: S. Fidan, M.D.
S. Izci
M. Tellice
E. Alizade
G. Açar
Publikationsdatum: 01.02.2015
Verlag: Urban & Vogel
Erschienen in: Herz / Ausgabe 1/2015
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI: https://doi.org/10.1007/s00059-013-3952-6

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ST elevation myocardial infarction after use of pseudoephedrine

Which is more dangerous, the common cold itself or the medication used for it?

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