Erschienen in:
01.10.2015 | Short Communication
Orthostatic hypotension is associated with decreased cerebrospinal fluid levels of chromogranin A in early stage of Parkinson disease
verfasst von:
Michaela Kaiserova, Hana Prikrylova Vranova, Jan Galuszka, David Stejskal, Katerina Mensikova, Jana Zapletalova, Jan Mares, Petr Kanovsky
Erschienen in:
Clinical Autonomic Research
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Ausgabe 5/2015
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Abstract
An association between the CSF chromogranin A (CgA) and orthostatic blood pressure changes was investigated in 20 patients in the early stage of Parkinson disease (PD). There was a positive correlation between the CSF CgA and diastolic blood pressure change, when CSF CgA levels were lower in patients with orthostatic hypotension (OH). Decreased CSF CgA may be useful in predicting OH in the early stage of PD.