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Herzschrittmachertherapie + Elektrophysiologie

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01.03.2015 | Original Contributions

Patients with atrial fibrillation complicated by coronary artery disease

Is a single value of sensitive cardiac troponin I on admission enough?

verfasst von: Dirk Bandorski, MD, Harilaos Bogossian, MD, Olaf Braun, MD, Gerrit Frommeyer, MD, Markus Zarse, MD, Reinhard Höltgen, MD, Christoph Liebetrau, MD

Erschienen in: Herzschrittmachertherapie + Elektrophysiologie | Ausgabe 1/2015

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Abstract

Background

Atrial fibrillation (AF) is the most common arrhythmia in the general population. Cardiac troponin I (cTnI) can be elevated in patients with AF without coexisting coronary artery disease (CAD). The aim of this study was to characterize the diagnostic accuracy and clinical usefulness of a cTnI assay for the diagnosis of CAD in patients with AF.

Methods

Patients with AF undergoing coronary angiography were included in the study. The workflow chart encompassed measuring of cTnI in all patients at admission and after 6 h.

Results

Patients with CAD were older (73.8 ± 7.6 vs. 65.3 ± 12.9 years) than patients without CAD; for all other characteristics, no significant differences were observed. Of the patients, 39 had CAD [12 patients one-vessel disease (VD), 14 patients 2-VD, 13 patients 3-VD] and 16 patients had acute myocardial infarction and were undergoing percutaneous coronary intervention. There was no significant difference in cTnI concentrations between patients without and with CAD at admission (0.02 vs. 0.03 ng/ml, respectively); however, a difference was noted after 6 h (0.03 vs. 0.06 ng/ml, respectively).

Conclusion

AF patients both without and with CAD showed similar cTnI concentrations at admission. A second validation of cTnI is mandatory for all patients.

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Titel: Patients with atrial fibrillation complicated by coronary artery disease
Is a single value of sensitive cardiac troponin I on admission enough?
verfasst von: Dirk Bandorski, MD
Harilaos Bogossian, MD
Olaf Braun, MD
Gerrit Frommeyer, MD
Markus Zarse, MD
Reinhard Höltgen, MD
Christoph Liebetrau, MD
Publikationsdatum: 01.03.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: Herzschrittmachertherapie + Elektrophysiologie / Ausgabe 1/2015
Print ISSN: 0938-7412
Elektronische ISSN: 1435-1544
DOI: https://doi.org/10.1007/s00399-015-0348-8

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