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Erschienen in: Der Nervenarzt 4/2015

01.04.2015 | Leitthema

Sarkopenie und Frailty in der Neurologie

verfasst von: W. Maetzler, M. Drey, Prof. Dr. A.H. Jacobs, MSc

Erschienen in: Der Nervenarzt | Ausgabe 4/2015

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Zusammenfassung

Sarkopenie und Frailty sind häufige, alltagsrelevante und lebensqualitätbeeinflussende geriatrische Syndrome. Über das Vorkommen dieser Syndrome bei und den Einfluss dieser Syndrome auf altersassoziierte/n neurologische/n Erkrankungen wie Parkinson-, Alzheimer-Erkrankung und Schlaganfall ist wenig bekannt. Dieser Übersichtsartikel stellt die Konzepte von Sarkopenie und Frailty vor, arbeitet die Relevanz der Symptome beim alten Menschen heraus und stellt dann die bis dato vorliegende Literatur zum Thema Sarkopenie/Frailty bei den genannten neurologischen Erkrankungen beispielhaft vor. Erste Studien weisen auf eine hohe Koinzidenz und einen großen Einfluss dieser Syndrome auf Parkinson-, Alzheimer-Erkrankung und Schlaganfall hin. Auch gibt es Hinweise auf gemeinsame Ursachen/Pathophysiologien von Sarkopenie/Frailty und z. B. der Alzheimer-Erkrankung. Zusammenfassend besteht ein Defizit an Wissen über die Zusammenhänge zwischen den beiden geriatrischen Syndromen Sarkopenie und Frailty und altersassoziierten neurologischen Erkrankungen. Eine umfassende und alltagsorientierte neurologische Therapie ist nur möglich, wenn die Interaktion dieser geriatrischen Syndrome mit neurologischen Erkrankungen besser verstanden und die gewonnenen Ergebnisse in Therapiekonzepte adäquat eingebettet werden.
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Metadaten
Titel
Sarkopenie und Frailty in der Neurologie
verfasst von
W. Maetzler
M. Drey
Prof. Dr. A.H. Jacobs, MSc
Publikationsdatum
01.04.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Der Nervenarzt / Ausgabe 4/2015
Print ISSN: 0028-2804
Elektronische ISSN: 1433-0407
DOI
https://doi.org/10.1007/s00115-014-4181-9

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