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29.01.2014 | CME Fortbildung

Schonen war gestern: Sport bei Krebspatienten

Wie gezieltes Training die Therapie unterstützen kann

verfasst von: Prof. Dr. Irenäus A. Adamietz

Erschienen in: CME | Ausgabe 1/2014

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Zusammenfassung

Sport und körperliche Aktivität sind wirksame Maßnahmen der Gesundheitsförderung. Ihre Rolle bei Krebspatienten wurde aber lange Zeit unterschätzt. Bei vielen Krebsarten erhöhen Bewegungsmangel, Adipositas und Fehlernährung das Erkrankungsrisiko und beeinflussen den Krankheitsverlauf. Umgekehrt verbessert regelmäßige körperliche Aktivität bei Krebspatienten nicht nur die körperliche Leistungsfähigkeit, sie reduziert auch die Nebenwirkungen der Therapie, hellt die Stimmung auf und steigert die Lebensqualität. Möglicherweise kann für bestimmte Krebserkrankungen sogar die tumorspezifische Sterblichkeit verringert werden. Die früher empfohlene Schonung gilt heute als problematisch. Stattdessen wird körperliche Aktivität in allen Phasen einer Krebserkrankung empfohlen, abhängig von der individuellen Belastbarkeit. Gezieltes Training kann die physische und psychische Situation der Patienten deutlich verbessern.

[1]

Dimeo FC, Thiel E (2008) Körperliche Aktivität und Sport bei Krebspatienten. Onkologe 14:31–37CrossRef

[2]

Fasching PA, Hübner J, Kleeberg UR (2009) Körperliche Bewegung und Sport zur Prävention und Behandlung von Krebskrankheiten. Onkologe 15:696–701CrossRef

[3]

Dimeo FC (2001) Effects of exercise on cancer-related fatigue. Cancer 92:1689–1693PubMedCrossRef

[4]

Dimeo FC (2001) Körperliche Aktivität und Krebs: eine Übersicht. Dtsch Z Sport-med 52:238–244

[5]

Hoffman-Goetz L, May KM, Arumugam Y (1994) Exercise training and mouse mammary tumour metastasis. Anticancer Res 14:2627–2631PubMed

[6]

Ainsworth BE, Haskell WL, Leon AS et al (1993) Compendium of physical activities: classification of energy costs of human physical activities. Med Sci Sports Exerc 25:71–80PubMedCrossRef

[7]

Ainsworth BE, Haskell WL, Whitt MC et al (2000) Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc 32(Suppl 9):S498–S504PubMedCrossRef

[8]

Irwin ML, McTiernan A, Bernstein L et al (2005) Relationship of obesity and physical activity with C-peptide, leptin and insulin-like growth factors in breast cancer survivors. Cancer Epidemiol Biomarkers Prev 14:2881–2888PubMedCentralPubMedCrossRef

[9]

Schmitz KH, Ahmed RL, Yee D (2002) Effects of a 9-month strength training intervention on insulin, insulin-like growth factor (IGF)-I, IGF-binding protein (IGFBP)-1, and IGFBP-3 in 30–50-year-old women. Cancer Epidemiol Biomarkers Prev 11:1597–1604PubMed

[10]

Zheng X, Cui XX, Huang MT et al (2008) Inhibitory effect of voluntary running wheel exercise on the growth of human pancreatic Panc-1 and prostate PC-3 xenograft tumors in immunodeficient mice. Oncol Rep 19:1583–1588PubMedCentralPubMed

[11]

Coyle YM (2008) Physical activity as a negative modulator of estrogen-induced breast cancer. Cancer Causes Control 19:1021–1029PubMedCrossRef

[12]

Pan SY, DesMeules M (2009) Energy intake, physical activity, energy balance and cancer: epidemiologic evidence. Methods Mol Biol 472:191–215PubMedCrossRef

[13]

Simoes EJ, Byers T, Coates RJ et al (1995) The association between leisure-time physical activity and dietary fat in American adults. Am J Public Health 85:240–244PubMedCrossRef

[14]

Orsini N, Mantzoros CS, Wolk A (2008) Association of physical activity with cancer incidence, mortality and survival: a population-based study of men. Br J Cancer 98:1864–1869PubMedCentralPubMedCrossRef

[15]

Leitzmann MF, Ahn J, Albanes D et al (2008) Diabetes mellitus and prostate cancer risk in the prostate, lung, colorectal and ovarian cancer screening trial. Cancer Causes Control 19:1267–1276PubMedCrossRef

[16]

Wannamethee SG, Shaper AG, Walker M (2001) Physical activity and risk of cancer in middle-aged men. Br J Cancer 85:1311–1316PubMedCentralPubMedCrossRef

[17]

Carpenter CL, Ross RK, Paganini-Hill A et al (2003) Effect of family history, obesity and exercise on breast cancer risk among postmenopausal women. Int J Cancer 106:96–102PubMedCrossRef

[18]

Gilliland FD, Li YF, Baumgartner K et al (2001) Physical activity and breast cancer risk in Hispanic and non-Hispanic white women. AmJ Epidemiol 154:442–450CrossRef

[19]

Schmidt ME, Steindorf K, Mutschelknauss E et al (2008) Physical activity and postmenopausal breast cancer: effect modification by breast cancer subtypes and effective periods in life. Cancer Epidemiol Biomarkers Prev 17:3402–3410PubMedCrossRef

[20]

Schnohr P, Gronbaek M, Petersen L et al (2005) Physical activity in leisure-time and risk of cancer: 14-year follow-up of 28,000 Danish men and women. Scand J Public Health 33:244–249PubMedCrossRef

[21]

World Cancer Research Fund International (WCRFI), American Institute of Cancer Research, Deutsches Institut für Ernährungsforschung (DIfE) et al (2003) Krebsprävention durch Ernährung. Forschung, Daten, Begründungen, Empfehlungen. Eigenverlag, Potsdam-Rehbrücke

[22]

Porock D, Kristjanson LJ, Tinnelly K et al (2000) An exercise intervention for advanced cancer patients experiencing fatigue: a pilot study. J Palliat Care 16:30–36PubMed

[23]

Heitkamp HC, Bott M (2001) Kolorektalkarzinome und körperliche Aktivität. Dtsch Ärztebl 10:A612–A618

[24]

Thune I, Lund E (1996) Physical activity and risk of colorectal cancer in men and women. Br J Cancer 73:1134–1140PubMedCentralPubMedCrossRef

[25]

Olson JE, Yang P, Schmitz K et al (2002) Differential association of body mass index and fat distribution with three major histologic types of lung cancer: evidence froma cohort of older women. Am J Epidemiol 156:606–615PubMedCrossRef

[26]

Colbert LH, Hartman TJ, Tangrea JA et al (2002) Physical activity and lung cancer risk in male smokers. Int J Cancer 98:770–773PubMedCrossRef

[27]

Torti DC, Matheson GO (2004) Exercise and prostate cancer. Sports Med 34:363–369PubMedCrossRef

[28]

Zeegers MP, Dirx MJ, Van den Brandt PA (2005) Physical activity and the risk of prostate cancer in the Netherlands cohort study, results after 9.3 years of follow-up. Cancer Epidemiol Biomarkers Prev 14:1490–1495PubMedCrossRef

[29]

Salazar-Martinez E, Lazcano-Ponce EC, Lira-Lira GG et al (2000) Case-control study of diabetes, obesity, physical activity and risk of endometrial cancer among Mexican women. Cancer Causes Control 11:707–711PubMedCrossRef

[30]

Trentham-Dietz A, Nichols HB, Hampton JM et al (2006) Weight change and risk of endometrial cancer. Int J Epidemiol 35:151–158PubMedCrossRef

[31]

Patel AV, Feigelson HS, Talbot JT et al (2008) The role of body weight in the relationship between physical activity and endometrial cancer: results froma large cohort of US women. Int J Cancer 123:1877–1882PubMedCrossRef

[32]

Smets EMA, Garssen B, Schuster-Uitterhoeve ALJ, Haes JCJM de (1993) Fatigue in cancer patients. Br J Cancer 68:220–224PubMedCentralPubMedCrossRef

[33]

Adamsen L, Quist M, Midtgaard J et al (2006) The effect of a multidimensional exercise intervention on physical capacity, well-being and quality of life in cancer patients undergoing chemotherapy. Support Care Cancer 14:116–127PubMedCrossRef

[34]

Courneya KS, Friedenreich CM, Quinney HA et al (2003) A randomized trial of exercise and quality of life in colorectal cancer survivors. Eur J Cancer Care (Engl) 12:347–357CrossRef

[35]

Courneya KS, Mackey JR, Bell GJ et al (2003) Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: cardiopulmonary and quality of life outcomes. J Clin Oncol 21:1660–1668PubMedCrossRef

[36]

Courneya KS, Segal RJ, Mackey JR et al (2007) Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: a multicenter randomized controlled trial. J Clin Oncol 25(28):4396–4404PubMedCrossRef

[37]

Daley AJ, Crank H, Saxton JM et al (2007) Randomized trial of exercise therapy in women treated for breast cancer. J Clin Oncol 25:1713–1721PubMedCrossRef

[38]

Dimeo F, Fetscher S, Lange W et al (1997) Effects of aerobic exercise on the physical performance and incidence of treatment-related complications after high-dose chemotherapy. Blood 90:3390–3394PubMed

[39]

Dimeo F, Tilmann MH, Bertz H et al (1997) Aerobic exercise in the rehabilitation of cancer patients after high dose chemotherapy and autologous peripheral stemcell transplantation. Cancer 79:1717–1722PubMedCrossRef

[40]

Dimeo F, Rumberger BG, Keul J (1998) Aerobic exercise as therapy for cancer fatigue. Med Sci Sports Exerc 30:475–478PubMedCrossRef

[41]

Dimeo F, Stieglitz RD, Novelli-Fischer U et al (1999) Effects of physical activity on the fatigue and psychologic status of cancer patients during chemotherapy. Cancer 85:2273–2277PubMedCrossRef

[42]

Mock V, Dow KH, Meares CJ et al (1997) Effects of exercise on fatigue, physical functioning and emotional distress during radiation therapy for breast cancer. Oncol Nurs Forum 24:991–1000PubMed

[43]

MacVicar MG, Winningham ML, Nickel JL (1989) Effects of aerobic interval training on cancer patients’functional capacity. Nurs Res 38:348–351PubMedCrossRef

[44]

Milne HM, Wallman KE, Gordon S, Courneya KS (2007) Effects of a combined aerobic and resistance exercise programin breast cancer survivors: a randomized controlled trial. Breast Cancer Res Treat 108(2):279–288. DOI 10.1007/s10549-007-9602-zPubMedCrossRef

[45]

Mock V, Barton B, Sheehan P et al (1994) A nursing rehabilitation programfor women with breast cancer receiving adjuvant chemotherapy. Oncol Nurs Forum 21:899–907PubMed

[46]

Ohira T, Schmitz KH, Ahmed RL, Yee D (2006) Effects of weight training on quality of life in recent breast cancer survivors: the weight training for breast cancer survivors (WTBS) study. Cancer 106:2076–2083PubMedCrossRef

[47]

Schwartz AL (2000) Exercise and weight gain in breast cancer patients receiving chemotherapy. Cancer Pract 8:231–237PubMedCrossRef

[48]

Schwartz AL, Mori M, Gao R (2001) Exercise reduces daily fatigue in women with breast cancer receiving chemotherapy. Med Sci Sports Exerc 33:718–723PubMedCrossRef

[49]

Dimeo FC, Thomas F, Raabe-Menssen C et al (2004) Effect of aerobic exercise and relaxation training on fatigue and physical performance of cancer patients after surgery. A randomised controlled trial. Support Care Cancer 12:774–779PubMedCrossRef

[50]

Dimeo F, Schwartz S, Fietz T et al (2003) Effects of endurance training on the physical performance of patients with hematological malignancies during chemotherapy. Support Care Cancer 11:623–628PubMedCrossRef

[51]

Schwartz AL, Thompson JA, Masood N (2002) Interferon-induced fatigue in patients with melanoma: a pilot study of exercise and methylphenidate. Oncol Nurs Forum 29:E85–E90PubMedCrossRef

[52]

Carlson LE, Smith D, Russell J et al (2006) Individualized exercise programfor the treatment of severe fatigue in patients after allogeneic hematopoietic stem-cell transplant: a pilot study. Bone Marrow Transplant 37:945–954PubMedCrossRef

[53]

Oechsle K, Jensen W, Schmidt T et al (2011) Physical activity, quality of life, and the interest in physical exercise programs in patients undergoing palliative chemotherapy. Support Care Cancer 19(5):613–619PubMedCrossRef

[54]

Holmes MD, Chen WY, Feskanich D et al (2005) Physical activity and survival after breast cancer diagnosis. JAMA 293:2479–2486PubMedCrossRef

[55]

Meyerhardt JA, Tepper JE, Niedzwiecki D et al (2004) Impact of body mass index on outcomes and treatment-related toxicity in patients with stage II and III rectal cancer: findings fromintergroup trial 0114. J Clin Oncol 22:648–657PubMedCrossRef

[56]

Courneya KS, McKenzie DC, Mackey JR et al (2013) Effects of exercise dose and type during breast cancer chemotherapy: multicenter randomized trial. J Natl Cancer Inst 105(23):1821–1832PubMedCrossRef

[57]

Segal RJ, Reid RD, Courneya KS et al (2003) Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. J Clin Oncol 21:1653–1659PubMedCrossRef

[58]

Calle EE, Rodriguez C, Walker-Thurmond K et al (2003) Overweight, obesity, and mortality fromcancer in a prospectively studied cohort of U.S. adults. N Engl J Med 348:1625–1638PubMedCrossRef

[59]

Caan BJ, Emond JA, Natarajan L et al (2006) Post-diagnosis weight gain and breast cancer recurrence in women with early stage breast cancer. Breast Cancer Res Treat 99:47–57PubMedCrossRef

[60]

Haydon AM, Macinnis RJ, English DR et al (2006) Effect of physical activity and body size on survival after diagnosis with colorectal cancer. Gut 55:62–67PubMedCrossRef

[61]

Fairey AS, Courneya KS, Field CJ et al (2003) Effects of exercise training on fasting insulin, insulin resistance, insulin-like growth factors, and insulin-like growth factor binding proteins in postmenopausal breast cancer survivors: a randomized controlled trial. Cancer Epidemiol Biomarkers Prev 12:721–727PubMed

[62]

Irwin ML, Varma K, Alvarez-Reeves M et al (2009) Randomized controlled trial of aerobic exercise on insulin and insulin-like growth factors in breast cancer survivors: the Yale exercise and survivorship study. Cancer Epidemiol Biomarkers Prev 18:306–313PubMedCentralPubMedCrossRef

[63]

Ligibel JA, Campbell N, Partridge A et al (2008) Impact of a mixed strength and endurance exercise intervention on insulin levels in breast cancer survivors. J Clin Oncol 26:907–912PubMedCrossRef

[64]

Schmitz KH, Ahmed RL, Hannan PJ et al (2005) Safety and efficacy of weight training in recent breast cancer survivors to alter body composition, insulin, and insulin-like growth factor axis proteins. Cancer Epidemiol Biomarkers Prev 14:1672–1680PubMedCrossRef

[65]

Basen-Engquist K, Hughes D, Perkins H et al (2008) Dimensions of physical activity and their relationship to physical and emotional symptoms in breast cancer survivors. J Cancer Surviv 2:253–261PubMedCentralPubMedCrossRef

[66]

Hsieh CC, Sprod LK, Hydock DS et al (2008) Effects of a supervised exercise intervention on recovery fromtreatment regimens in breast cancer survivors. Oncol Nurs Forum 35:909–915PubMedCentralPubMedCrossRef

[67]

Al-Majid S, Waters H (2008) The biological mechanisms of cancer-related skeletal muscle wasting: the role of progressive resistance exercise. Biol Res Nurs 10:7–20PubMedCrossRef

[68]

Rank M et al (2012) Sporttherapie bei Krebserkrankungen. Grundlagen-Diagnostik-Praxis. Schattauer, Stuttgart

[69]

Dimeo F (2004) Standards in der Sportmedizin: körperliche Aktivität und Krebs. Dtsch Z Sportmed 4:106–107

Titel: Schonen war gestern: Sport bei Krebspatienten
Wie gezieltes Training die Therapie unterstützen kann
verfasst von: Prof. Dr. Irenäus A. Adamietz
Publikationsdatum: 29.01.2014
Verlag: Springer-Verlag
Erschienen in: CME / Ausgabe 1/2014
Print ISSN: 1614-371X
Elektronische ISSN: 1614-3744
DOI: https://doi.org/10.1007/s11298-014-0003-4

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