Skip to main content
Erschienen in: European Child & Adolescent Psychiatry 9/2014

01.09.2014 | Brief Report

Sexual maturation among youth with ADHD and the impact of stimulant medication

verfasst von: Brian Greenfield, Lily Hechtman, Annamarie Stehli, Timothy Wigal

Erschienen in: European Child & Adolescent Psychiatry | Ausgabe 9/2014

Einloggen, um Zugang zu erhalten

Abstract

Objective

Evaluate the differences in achieving puberty between ADHD and non-ADHD participants and the effects of medication on that process among ADHD participants.

Procedure

A subset of participants with ADHD from the Multimodal Treatment study of ADHD (n = 342) were compared with respect to Tanner staging to participants from a comparison group without ADHD (n = 159) at the 36-month follow-up assessment. Further comparisons were made for Tanner stages and Auxology of the participants in the ADHD group who were always (n = 61), never (n = 56), newly (n = 74) and inconsistently (n = 116) treated with stimulants.

Results

No statistically significant differences in Tanner stages of sexual development were found between the ADHD and non-ADHD groups at the age of assessment (between 10 and 14 years of age) or among the ADHD medication subgroups, although a trend was observed for stimulant-associated delayed pubertal initiation using auxological analysis.

Conclusion

Children with or without ADHD did not differ in Tanner stages at the 3-year follow-up assessment, and exposure to stimulant medication does not appear to affect sexual development within this age range.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Mattison DR, Plant TM, Lin HM, Chen HC, Chen JJ, Twaddle NC, Doerge D, Slikker W Jr, Patton RE, Hotchkiss CE, Callicott RJ, Shradder SM, Turner TW, Kesner JS, Petibone TM, Morris SM (2011) Pubertal delay in non-human primates (macaca mulatta) treated with methylphenidate. PNAS 108(39):16301–16306PubMedCentralPubMedCrossRef Mattison DR, Plant TM, Lin HM, Chen HC, Chen JJ, Twaddle NC, Doerge D, Slikker W Jr, Patton RE, Hotchkiss CE, Callicott RJ, Shradder SM, Turner TW, Kesner JS, Petibone TM, Morris SM (2011) Pubertal delay in non-human primates (macaca mulatta) treated with methylphenidate. PNAS 108(39):16301–16306PubMedCentralPubMedCrossRef
2.
Zurück zum Zitat Tanner JM (1962) Growth at adolescence. 2nd edn., Oxford Tanner JM (1962) Growth at adolescence. 2nd edn., Oxford
3.
Zurück zum Zitat Bock R, du Toit S, Thissen C (2003) Auxological analysis of longitudinal measurements of human stature, vol version 3. Lincolnwood Bock R, du Toit S, Thissen C (2003) Auxological analysis of longitudinal measurements of human stature, vol version 3. Lincolnwood
4.
Zurück zum Zitat Smith BH, Pelham WE Jr, Gnagy E, Molina B, Evans S (2000) The reliability, validity, and unique contributions of self-report by adolescents recieving treatment for attention-deficit/hyperactivity disorder. J Consult Clin Psychol 68(3):489–499PubMedCrossRef Smith BH, Pelham WE Jr, Gnagy E, Molina B, Evans S (2000) The reliability, validity, and unique contributions of self-report by adolescents recieving treatment for attention-deficit/hyperactivity disorder. J Consult Clin Psychol 68(3):489–499PubMedCrossRef
5.
Zurück zum Zitat MTA Cooperative Group (2004) National Institute of Mental Health Multimodal Treatment Study of ADHD follow-up: Changes in effectiveness and growth after the end of treatment. Pediatrics 113:762–769CrossRef MTA Cooperative Group (2004) National Institute of Mental Health Multimodal Treatment Study of ADHD follow-up: Changes in effectiveness and growth after the end of treatment. Pediatrics 113:762–769CrossRef
6.
Zurück zum Zitat Elkin E (2004) Beyond binary outcomes: PROC LOGISTIC to model ordinal and nominal dependent variables. Paper presented at the Western Users of SAS software Elkin E (2004) Beyond binary outcomes: PROC LOGISTIC to model ordinal and nominal dependent variables. Paper presented at the Western Users of SAS software
7.
Zurück zum Zitat Schlossberger NM, Turner RA, Irwin CE Jr (1992) Validity of self-report of pubertal maturation in early adolescents. J Adolesc Health 12:109–113CrossRef Schlossberger NM, Turner RA, Irwin CE Jr (1992) Validity of self-report of pubertal maturation in early adolescents. J Adolesc Health 12:109–113CrossRef
8.
Zurück zum Zitat Biederman J, Faraone SV, Monuteaux MC, Plunkett EA, Gifford J, Spencer T (2003) Growth deficits and attention deficit/hyperactivity disorder revisited: impact of gender, development, and treatment. Pediatrics 111:1010–1016PubMedCrossRef Biederman J, Faraone SV, Monuteaux MC, Plunkett EA, Gifford J, Spencer T (2003) Growth deficits and attention deficit/hyperactivity disorder revisited: impact of gender, development, and treatment. Pediatrics 111:1010–1016PubMedCrossRef
9.
Zurück zum Zitat Safer DJ, Allen RP, Barr E (1972) Depression of growth in hyperactive children on stimulant drugs. New Engl J Med 287:217–220PubMedCrossRef Safer DJ, Allen RP, Barr E (1972) Depression of growth in hyperactive children on stimulant drugs. New Engl J Med 287:217–220PubMedCrossRef
10.
Zurück zum Zitat Poulton AC, Cowell CT (2003) Slowing of growth in height and weight on stimulants: a characteristic pattern. J Paediatr Child Health 39:180–185PubMedCrossRef Poulton AC, Cowell CT (2003) Slowing of growth in height and weight on stimulants: a characteristic pattern. J Paediatr Child Health 39:180–185PubMedCrossRef
Metadaten
Titel
Sexual maturation among youth with ADHD and the impact of stimulant medication
verfasst von
Brian Greenfield
Lily Hechtman
Annamarie Stehli
Timothy Wigal
Publikationsdatum
01.09.2014
Verlag
Springer Berlin Heidelberg
Erschienen in
European Child & Adolescent Psychiatry / Ausgabe 9/2014
Print ISSN: 1018-8827
Elektronische ISSN: 1435-165X
DOI
https://doi.org/10.1007/s00787-014-0521-3

Weitere Artikel der Ausgabe 9/2014

European Child & Adolescent Psychiatry 9/2014 Zur Ausgabe

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.