P1 Inhibition of jak/stat3 signaling pathway by small molecule r548 prevents inflammation in experimental murine lung injury model
V. Karavana1, I. Smith2, G. Kanellis3, I. Sigala1, T. Kinsella2, S. Zakynthinos1
1George P. Livanos and Marianthi Simou Laboratories, Athens, Greece; 2Rigel Pharmaceuticals, Inc, South San Francisco, CA, USA; 3Evangelismos Hospital, Athens, Greece
P2 Stable genetic alterations of CXCR7 regulate the CXCL12/CXCR7 axis, a new "passport" ± for the homing of mscs
L. Liu, J. Chen, X. Zhang, A. Liu, F. Guo, S. Liu, Y. Yang, H. Qiu
Department of Critical Care Medicine, Nanjing Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China
P3 Withdrawn
P4 Spectrum study severe hypoxemia: prevalence, treatment and outcome in 2016
D. G. Grimaldi1, SR The SRLF Trial Group2
1Hôpital Erasme, Brussels, Belgium; 2SRLF, Paris, France
All hypoxemic n = 859 | Mild hypoxemia n = 440 | Moderate hypoxemia n = 345 | Severe hypoxemia n = 74 | P value | |
---|---|---|---|---|---|
Age | 64 (53–73) | 65 (54–74) | 65 (53–73) | 58 (47–69) | 0.006 |
Sex | 586 (68) | 298 (68) | 236 (68) | 52 (70) | 0.91 |
Medical patients | 675 (79) | 327 (75) | 281 (82) | 67 (91) | 0.004 |
SAPS-2 | 43 (31–57) | 42 (30–56) | 43 (31–57) | 45 (34–61) | 0.32 |
ARDS (Berlin definition) | 183 (21) | 68 (16) | 85 (25) | 30 (41) | <0.001 |
Invasive ventilation | 525 (61) | 239 (54) | 231 (67) | 55 (74) | 0.001 |
ICU length of stay | 16 (7–32) | 15 (7–32) | 16 (8–31) | 18 (7–37) | 0.89 |
ICU mortality | 225 (27) | 92 (21) | 96 (27) | 37 (50) | <0.00 |
P5 Correlation of horowitz ratio with oxygen saturation index in ARDS
E. Kaya, O. Acicbe, I. Kayaalp, S. Asar, M. Dogan, G. Eren, O. Hergunsel
Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey
P6 Ards features of the severe burn patients from colective tragedy
D. Pavelescu, I. Grintescu, L. Mirea
Emergency Hospital Floreasca, Bucharest, Romania
P7 Relationship between energy load and lung regional inflation status in ARDS patients: a CT scan study
M. Guanziroli1, M. Gotti2, A. Marino1, M. Cressoni1, G. Vergani1, C. Chiurazzi3, D. Chiumello1, L. Gattinoni4
1Università degli Studi di Milano, Milano, Italy; 2ASST Santi Paolo e Carlo, Milano, Italy; 3Humanitas, Rozzano, Italy; 4University of Gottingen, Gottingen, Germany
P8 Relationship between total or lung superimposed pressure and absolute esophageal pressure in ARDS: a CT scan study
M. Guanziroli1, M. Gotti2, G. Vergani1, M. Cressoni1, C. Chiurazzi3, A. Marino1, S. Spano1, D. Chiumello1, L Gattinoni4
1Università degli Studi di Milano, Milano, Italy; 2ASST Santi Paolo e Carlo, Milano, Italy; 3Humanitas, Rozzano, Italy; 4University of Gottingen, Gottingen, Germany
-
- total SP (cmH2O) = 11.97 + 0.17 * Pes (cmH2O), r2 = 0.08, p < 0.01
-
- lung SP (cmH2O) = 3.47 + 0.13 * Pes (cmH2O), r2 = 0.07, p = 0.01
P9 Relationship between energy load and lung inhomogeneity in ARDS patients: a CT scan study
M. Guanziroli1, M. Gotti2, G. Vergani1, A. Marino1, M. Cressoni1, C. Chiurazzi3, D. Chiumello1, L. Gattinoni4
1Università degli Studi di Milano, Milano, Italy; 2ASST Santi Paolo e Carlo, Milano, Italy; 3Humanitas, Rozzano, Italy; 4University of Gottingen, Gottingen, Germany
-
PEEP 5: Δ inhomogeneity(%) = 4.38–0.01*EL(mJ), r2 = 0.31, p < 0.001
-
PEEP 15: Δ inhomogeneity(%) = 2.78–0.002*EL(mJ), r2 = 0.26, p < 0.0001.
P10 Does galunisertib reduce edema in experimental ARDS? An exploratory study
F. Massaro1, A. Moustakas2, S. Johansson2, A. Larsson3, G. Perchiazzi3
1Policlinico di Bari, Bari, Italy; 2Uppsala University Biomedical Center, Uppsala, Sweden; 3Akademiska Sjukhuset, Uppsala University, Uppsala, Sweden
P11 Stable over expression of p130 and E2F4 makes a difference on multipotential differentiation in bone marrow derived MSCs
X. W. Zhang, F. M. Guo, J. X. Chen, M. Xue, Y. Yang, H. B. Qiu
Department of Critical Care Medicine, Nanjing Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China
P12 The homing and protective effects of mesenchymal stem cells overexpressing CXCR7 in LPS-induced acute respiratory distress syndrome mice
J. X. Chen, L. Liu, L. Yang, X. W. Zhang, F. M. Guo, Y. Yang, H. B. Qiu
Department of Critical Care Medicine, Nanjing Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China
P13 Independent lung ventilation (ilv) in ICU-forgotten, neglected or useless?
M. Fister, R. Knafelj
Rihard Knafelj, Ljubljana, Slovenia
P14 Initiation of mechanical ventilation with the lower threshold of tidal volume in ARDS
M. A. Suzer1, M. E. Kavlak2, H. K. Atalan3, B. Gucyetmez4, N. Cakar4
1Cankaya Hospital, Ankara, Turkey; 2Atasehir Memorial Hospital, Istanbul, Turkey; 3Acibadem Fulya Hospital, Istanbul, Turkey; 4Acibadem University School of Medicine, Istanbul, Turkey
P15 Lung protective ventilation: what is the effect of education on tidal volume and p0.1 values?
D. Weller, A. F. Grootendorst, A. Dijkstra, T. M. Kuijper, B. I. Cleffken
Maasstad Hospital, Rotterdam, Netherlands
Controle group | Intervention group | P value | |
---|---|---|---|
n = 17 | n = 14 | ||
Male | 10 (58.8) | 10 (71.4) | |
Age | 70.4 ± 7.3 | 64.9 ± 6.9 | 0.04 |
Current weight | 73.4 ± 13.5 | 93.4 ± 27.3 | 0.02 |
IBW | 63.1 ± 9.4 | 65.3 ± 9.3 | |
Cardiac | 5 (29.4) | 1 (7.1) | |
Surgical | 8 (47,1) | 2 (14.3) | |
Medical | 4 (23.5) | 11 (78.6) | 0.01 |
SOFA score | 14.3 ± 2.3 | 12.3 ± 3.8 |
Controle group | Intervention group | P value | |
---|---|---|---|
n = 17 | n = 14 | ||
SpO2 % | 96.8 ± 1.3 | 96.4 ± 1.5 | 0.45 |
etCO2 mmHg | 33.1 ± 4.0 | 37.8 ± 8.1 | 0.07 |
RR min. | 19.4 ± 3.6 | 22.6 ± 4.8 | 0.05 |
AMVe L/min | 9,6 ± 1,8 | 10,2 ± 2,2 | 0,44 |
Tve ml | 541.7 ± 120.7 | 476.2 ± 66.8 | 0.07 |
PEEP cmH2O | 9.2 ± 2.2 | 10.1 ± 3.1 | 0.38 |
Ppeak cmH2O | 19.3 ± 3.4 | 23.8 ± 5.8 | 0.02 |
Pmean cmH2O | 12 ± 2.1 | 13.8 ± 3.6 | 0.1 |
FiO2 | 0.4 ± 0.1 | 0.5 ± 0.1 | 0.46 |
P0.1 cmH2O | 1.7 ± 0.9 | 1.8 ± 1 | 0.75 |
PS cmH2O | 9.3 ± 3.5 | 13 ± 4 | 0.01 |
PF-ratio | 217.9 ± 56.1 | 209.2 ± 57.7 | 0.68 |
Tve ml/kg/IBW | 8.6 ± 1.7 | 7.4 ± 1.4 | 0.04 |
P16 Intra-abdominal pressure adjusted positive end-expiriatory pressure – a pilot study
A. Regli1, B. De Keulenaer1, P. Van Heerden2
1Fiona Stanley Hospital, Perth, Australia; 2Hadassah University Hospital, Jerusalem, Israel
P17 Withdrawn
P18 Withdrawn
P19 Neurally adjusted ventilatory assist versus pressure support in prolonged mechanical ventilation: a randomised feasibility study
D. Hadfield1, P. A. Hopkins2, B. Penhaligon2, F. Reid1, N. Hart3, G. F. Rafferty1
1King’s College London, London, UK; 2King’s College Hospital, London, UK; 3Guy’s and St Thomas’ Hospital, London, UK
Variable | NAVA | Control |
---|---|---|
Age, years | 68 (53, 74.5) | 74(66, 79) |
Sex, number male | 18 (72%) | 15 (70%) |
APACHE II | 20 (15.5, 25.5) | 21 (13, 22) |
Chronic Obstructive Pulmonary Disease | 9 (36%) | 8 (34.8%) |
Heart Failure | 17 (60.7%) | 16 (69.6%) |
Acute Respiratory Distress Syndrome | 4 (14.3%) | 3 (13%) |
Protocol compliance, % (95% CI)a
| 68.2% [47.3–83.6] | NA |
Adherence with allocated ventilation mode | 82.3% (19.7, 97.6) n = 22 | 100% (100, 100) n = 21 |
Ventilator free days to D28, days | 18 [8, 24] | 19 [0, 23] |
ICU stay from randomisation (survivors), days | 9.1 (6, 21.9) n = 19 | 12 (7.1, 41.8) n = 16 |
Hospital stay from randomisation (survivors), days | 20.7 (12.3, 35.6) n = 18 | 31.5 (14.8, 57.6) n = 13 |
ICU mortality | 5 (17.9%) | 7 (30.4%) |
P20 Effects of prone position and recruitment manoeuvres on gas exchange and regional respiratory mechanics
G. Grasselli1, T. Mauri2, M. Lazzeri3, E. Carlesso2, B. Cambiaghi4, N. Eronia4, E. Maffezzini4, A. Bronco4, C. Abbruzzese1, N. Rossi1, G. Foti4, G. Bellani4, A. Pesenti2
1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy; 2University of Milan, Milan, Italy; 3University of Ferrara, Ferrara, Italy; 4University of Milan-Bicocca, Monza, Italy
Supine pre-RM | Supine post-RM | Prone pre-RM | Prone post-RM | p-value position | p-value RM | p-vaule interaction | |
---|---|---|---|---|---|---|---|
PaO2/FiO2 [mmHg] | 144 ± 63 | 147 ± 65 | 172 ± 77 | 191 ± 92 | 0.109 | 0.054 | 0.046 |
Homogeneity index | 1.79 ± 0.80 | 1.71 ± 0.77 | 1.33 ± 0.55 | 1.28 ± 0.54 | 0.272 | 0.183 | 0.281 |
Crs [ml/cmH2O] | 41 [23–46] | 37 [22–47] | 37 [24–50] | 36 [24–48] | 0.810 | 0.811 | 0.911 |
Crs non-dep [ml/cmH2O] | 23 [14–32] | 23 [15–33] | 13 [9–28] | 12 [10–29] | 0.009 | 0.426 | 0.494 |
Crs dep [ml/cmH2O] | 12 [8–19] | 9 [8–19] | 17 [13–23] | 16 [13–20] | 0.006 | 0.106 | 0.845 |
P21 Feasibility of the lateral-trendelenburg vs semi recumbent body position – the GRAVITY-VAP TRIAL
G. Li Bassi1, M. Panigada2, O. Ranzani1, T. Kolobow3, A. Zanella 2, M. Cressoni4, L. Berra5, V. Parrini6, H. Kandil7, G. Salati8, S. Livigni9, S. Livigni10, A. Amatu10, M. Girardis11, M. Barbagallo12, G. Moise13, G. Mercurio14, A. Costa 12, A. Vezzani12, S. Lindau15, J. Babel16, M. Cavana17, A. Torres1
1Hospital Clinic, Barcelona, Spain; 2Policlinico di Milano, Milan, Italy; 3National Institutes of Health, Bethesda, USA; 4Ospedale San Paolo, Milan, Italy; 5Massachusetts General Hospital, Boston, USA; 6Ospedale Nuovo del Mugello, Borgo San Lorenzo, Italy; 7Gruppo Ospedaliero San Donato, San Donato Milanese, Italy; 8Arcispedale S. Maria Nuova, Reggio Emilia, Italy; 9Ospedale San Giovanni Bosco, Torino, Italy; 10Policlinico San Matteo, Pavia, Italy; 11Policlinico di Modena, Modena, Italy; 12Azienda Ospedaliero-Universitaria di Parma, Parma, Italy; 13Ospedale Citta di Sesto San Giovanni, Sesto San Giovanni, Italy; 14Policlinico Gemelli, Roma, Italy; 15University Hospital Frankfurt, Frankfurt, Germany; 16University Hospital Zagreb, Zagreb, Croatia; 17Ospedale Santa Chiara, Trento, Italy
P22 Lateral-trendelenburg vs. semi recumbent body position for the prevention of ventilator-associated pneumonia – the GRAVITY-VAP TRIAL
M. Panigada1, G. Li Bassi2, O. T. Ranzani2, T. Kolobow3, A. Zanella1, M. Cressoni4, L. Berra5, V. Parrini6, H. Kandil7, G. Salati8, S. Livigni9, A. Amatu10, M. Girardis11, M. Barbagallo12, G. Moise13, G. Mercurio14, A. Costa12, A. Vezzani12, S. Lindau15, J. Babel16, M. Cavana17, A. Torres2
1Policlinico di Milano, Milan, Italy; 2Hospital Clinic, Barcelona, Spain; 3National Institutes of Health, Bethesda, USA; 4Ospedale San Paolo, Milan, Italy; 5Massachussets General Hospital, Boston, USA; 6Ospedale Nuovo del Mugello, Borgo San Lorenzo, Italy; 7Gruppo Ospedaliero San Donato, San Donato Milanese, Italy; 8Arcispedale S. Maria Nuova, Reggio Emilia, Italy; 9Ospedale San Giovanni Bosco, Torino, Italy; 10Policlinico San Matteo, Pavia, Italy; 11Policlinico di Modena, Modena, Italy; 12Azienda Ospedaliero-Universitaria di Parma, Parma, Italy; 13Ospedale di Sesto San Giovanni, Sesto San Giovanni, Italy; 14Policlinico Gemelli, Rome, Italy; 15University Hospital Frankfurt, Frankfurt, Germany; 16University Hospital Center Zagreb, Zagreb, Croatia; 17Ospedale Santa Chiara, Trento, Italy
P23 Effects of lateral position and open chest on partitioned respiratory mechanics during thoracic surgery
M. Umbrello, M. Taverna, P. Formenti, G. Mistraletti, F. Vetrone, A. Marino, G. Vergani, A. Baisi, D. Chiumello
Ospedale San Paolo, Università degli Studi di Milano, Milano, Italy
P24 Manual versus closed loop control of oxygenation parameters during invasive ventilation: effects on hyperoxemia
A. G. Garnero1, D. N. Novotni2, J. A. Arnal1
1Hôpital Sainte Musse, Toulon, France; 2Hamilton medical, Bonaduz, Switzerland
P25 Withdrawn
P26 Predicting the presence of spontaneous breathing in mechanically ventilated patients
M. Urner, E. Fan, M. Dres, S. Vorona, L. Brochard, N. D. Ferguson, E. C. Goligher
University of Toronto, Toronto, Canada
P27 Mechanical ventilation training using flipped-classroom with a one-hour face-to-face tutorial
C. Leung, G. Joynt, W. Wong, A. Lee, C. Gomersall
Chinese University of Hong Kong, Sha Tin NT, Hong Kong
P28 Predictors of prolonged mechanical ventilation after lung transplants: a retrospective cohort study
S. Poels, M. Casaer, M. Schetz, G. Van den Berghe, G. Meyfroidt
UZ Leuven, Leuven, Belgium
Preoperative risk factors | |
Age med (IOR) | 57.5 (43.25/61.75) |
BMI mean (SD) | 22.96 (+ − 3.71) |
APACHE II med (IQR) | 19.5 (18/24.75) |
COPD N(%) | 17 (47) |
Pulmonary hypertension N(%) | 2 (5.5) |
Other (MUCO, Kartagener, Hemangioblastoma) | 4 (11) |
Lung fibrosis N(%) | 13 (36) |
Preoperative use of corticosteroids N(%) | 15 (41.6) |
Preoperative use of oxygen N(%) | 16 (44) |
Postoperative risk factors | |
ECMO N(%) | 7 (19.4) |
Sedation with Dexmedetomidine | 24 (66) |
Tracheostomy N(%) | 2 (5.5) |
Reperfusion edema N(%) | 14 (38) |
P29 The effect of hypoxaemia on cognitive outcome in adult patients with severe acute respiratory failure treated with conventional mechanical ventilation or extracorporeal membrane oxygenation: a systematic review of the literature
B. Holzgraefe1, L. B. Von Kobyletzki2, A. Larsson3
1Karolinska Institutet, Stockholm, Sweden; 2Lund University, Karlstad University, Lund, Sweden; 3Uppsala University, Uppsala, Sweden
P30 Patterns of morpho-functional pulmonary recovery after total structural consolidation
G. Cianchi1, F. Becherucci1, S. Batacchi1, M. Cozzolino1, F. Franchi2, S. Di Valvasone1, M. C. Ferraro1, A. Peris1
1Careggi Teaching Hospital, Florence, Italy; 2University of Siena, Siena, Italy
P31 Initial ECMO experience in a Thai tertiary hospital
H. Phiphitthanaban, P. Wacharasint, V. Wongsrichanalai, A. Lertamornpong, O. Pengpinij, A. Wattanathum, N. Oer-areemitr
Phramonkutklao hospital, Bangkok, Thailand
P32 Cannula-related deep vein thrombosis during extracorporeal membrane oxygenation (ECMO) treatment do not affect mortality and length of stay in intensive care unit
M. Boddi, G. Cianchi, E. Cappellini, M. Ciapetti, S. Batacchi, G. Di Lascio, M. Bonizzoli, M. Cozzolino, A. Peris
Careggi Teaching Hospital, Florence, Italy
P33 Survival of septic patients with refractory ARDS requiring veno-venous ECMO
C. Lazzeri, G. Cianchi, M. Bonizzoli, G. Di Lascio, M. Cozzolino, A. Peris
Careggi Teaching Hospital, Florence, Italy
P34 Rescue ecmo therapy in h1n1 induced ARDS – successful experience from Belarus
M. L. Katsin, M. Y. Hurava, A. M. Dzyadzko
Republican Scientific and Practical Center for Organ and Tissue Transplantation, Minsk, Belarus
P35 Long-term ecmo without anticoagulation in patients with severe thrombocytopenia
A. Hermann, P. Schellongowski, A. Bojic, K. Riss, O. Robak, W. Lamm, W. Sperr, T. Staudinger
Medical University of Vienna, Vienna, Austria
P36 Long-term quality of life after extracorporeal membrane oxygenation in ards patients: an Italian tertiary centre experience
L. Tadini Buoninsegni, M. Bonizzoli, M. Cozzolino, J. Parodo, A. Ottaviano, L. Cecci, E. Corsi, V. Ricca, A. Peris
Careggi Teaching Hospital, Florence, Italy
P37 Advance Organ Support (ADVOS) based on albumin dialysis, a new method for CO2 removal and pH stabilization
A. Perez Ruiz de Garibay, B. Ende-Schneider, C. Schreiber, B. Kreymann
Hepa Wash GmbH, Munich, Germany
P38 ECCO2 removal with a membrane oxygenator (Prismalung ®) integrated in a CRRT plataform (prismaflex ®): a feasibility study
F. Turani 1, M. Resta2, D. Niro2, P. Castaldi3, G. Boscolo4, G. Gonsales5, S. Martini1, A. Belli1, L. Zamidei5, M. Falco1
1Aurelia and European Hospital, Rome, Italy; 2Istituti clinici S Donato MI, Milan, Italy; 3Marino Hospital, Cagliari, Italy; 4Ospedale dell’ Angelo, Mestre, Italy; 5Santo Stefano Hospital, Prato, Italy
T0 | T1 | T2 | |
---|---|---|---|
PH | 7.23 ± 0.07 | 7.34 ± 0.1 | 7.37 ± 0.1* |
PaCO2 mmHg | 86 ± 26 | 56 ± 16** | 51 ± 15** |
CO2 removal ml/min | 53 ± 14 | 57 ± 15 | 55 ± 17 |
Creatinine mg/dL | 2.13 ± 2 | 1.96 ± 0.8 | 1.41 ± 0.7 |
Blood flow ml/min | 250 ± 28 | 330 ± 34 | 330 ± 41 |
P39 Ultra-low blood flow veno-venous extracorporeal CO2 removal (ECCO2R) with acidification and regional anticoagulation together with hemodiafiltration
T. Lamas1, J. Mendes2
1Egas Moniz Hosp., Lisboa, Portugal; 2Fernando da Fonseca Hosp., Lisboa, Portugal
P40 Effect of flow and temperature on comfort during high flow nasal cannula
A. Galazzi1, T. Mauri1, B. Benco1, F. Binda1, L. Masciopinto1, M. Lazzeri2, E. Carlesso1, A. Lissoni1, G. Grasselli1, I. Adamini1, A. Pesenti1
1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, University of Milan, Milano, Italy; 2Sant’Anna Hospital, University of Ferrara, Ferrara, Italy
HFNC 30 l/min-31 °C | HFNC 30 l/min–37 °C | HFNC 60 l/min–31 °C | HFNC 60 l/min–37 °C | P-value for flow | P-value for temp | P-value for interaction | |
---|---|---|---|---|---|---|---|
Comfort scale | 5 [4–5] | 3 [1–3] | 3 [2–4] | 2 [0–3] | 0.015 | <0.001 | 0.145 |
Modified Borg scale | 3 [2–5] | 4 [2–5] | 5 [2–6] | 5 [2–5] | 0.461 | 0.718 | 0.283 |
SpO2 % | 97 [94–99] | 97 [95–99] | 97 [96–99] | 98 [96–99] | 0.026 | 0.598 | 0.190 |
RR (bpm) | 21 [20–25] | 23 [20–27] | 22 [20–24] | 22 [21–25] | 0.815 | 0.248 | 0.332 |
FC (bpm) | 87 [73–97] | 89 [77–98] | 86 [74–97] | 87 [73–101] | 0.858 | 0.081 | 0.511 |
PAS (mmHg) | 117 [104–131] | 117 [106–132] | 115 [105–134] | 116 [109–135] | 0.805 | 0.126 | 0.979 |
P41 High flow nasal cannula prevent reintubation in post-extubated critically ill patients: a systematic review and meta-analysis
T. Thamjamrassri, J. Watcharotayangul, P. Numthavaj, S. Kongsareepong
Mahidol university, Bangkok, Thailand
P42 The role of high flow nasal cannula oxygen therapy in the intensive care unit
J. Higuera, D. Cabestrero, L. Rey, G. Narváez, A. Blandino, M. Aroca, S. Saéz, R. De Pablo
Ramón y Cajal University Hospital, Madrid, Spain
P43 High flow nasal cannula in immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis
A. Mohamed, M. Sklar, L. Munshi
Sinai Health System, Toronto, Canada
P44 Setting high flow nasal cannula to maximize physiologic benefits
T. Mauri1, M. Lazzeri2, L. Alban2, C. Turrini2, M. Panigada3, P. Taccone3, E. Carlesso1, C. Marenghi3, S. Spadaro2, G. Grasselli3, C. Volta 2, A. Pesenti1
1University of Milan, Milan, Italy; 2University of Ferrara, Ferrara, Italy; 3Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy
P45 The role of high flow nasal cannula oxygen therapy in hematological patients with severe respiratory failure
J. Higuera, D. Cabestrero Alonso, A. Blandino, G. Narváez, L. Rey González, M. Aroca, S. Saéz, R. De Pablo
Ramón y Cajal University Hospital, Madrid, Spain
P46 Withdrawn
P47 The advanced airway management in the out-of-hospital setting: a comparison between endotracheal intubation and extra-glottic devices in terms of mortality and outcome
A. Franci, G. Stocchi, G. Cappuccini, F. Socci, M. Cozzolino, C. Guetti, P. Rastrelli, A. Peris
Careggi Teaching Hospital, Florence, Italy
Patients with ETT | Patients with EGD | p | |
---|---|---|---|
BAL POSITIVITY at admittance in ICU (%) | 57/154 (37%) | 14/33 (42%) | NS |
PaO2/FiO2 48H | 289 (±99.2) | 272 (±127.04) | NS |
Lenght Of Stay (days) | 8.2 (±7.91) | 8.3 (±9.55) | NS |
Mortality after 7 Days | 37/154 (24.02%) | 14/33 (42.42%) | 0.047 |
Survival in MV vs BVM | 59/60 (98.33%) vs 82/94 (87.23%) | - | 0.033 |
P48 Arterial oxygenation and hemodynamics during extrathoracic negative pressure in a porcine model of lung injury
A. Nestorowicz1, J. Glapinski2, A. Fijalkowska-Nestorowicz3, J. Wosko4
1Medical Univesity, Lublin, Poland; 2Wroclaw University of Technology, Wroclaw, Poland; 3Medical University, Lublin, Poland; 4SPSK No4, Lublin, Poland
P49 Influence of extrathoracic negative pressure on mechanics of atelectatic lung during IPPV
A. Fijalkowska-Nestorowicz1, J. Glapinski2, J. Wosko3
1Medical University, Lublin, Poland; 2Wroc3aw University of Technology, Wroclaw, Poland; 3SPSK No4, Lublin, Poland
Before | 0 (cmH2O) | −4 (cmH2O) | −8 (cmH2O) | −12 (cmH2O) | −16 (cmH2O) | |
---|---|---|---|---|---|---|
Pawpeak (cmH2O) | 19.9 ± 2.9* | 29.4 ± 3.8 | 30.5 ± 6 | 26.2 ± 5.9 | 24.6 ± 5.9* | 25.5 ± 4.6* |
Cdyn (ml/cmH2O) | 30.9 ± 4.5* | 21.4 ± 8.9 | 20 ± 5.7 | 21.6 ± 5.8 | 23.1 ± 5.8 | 21.7 ± 3.9 |
R (cmH2O/l/s) | 10.3 ± 2.6 | 13.3 ± 4.9 | 10.5 ± 3.8 | 7.8 ± 1.9* | 6.7 ± 1.4* | 6.4 ± 1.2* |
PaO2/FIO2 (mmHg) | 552 ± 56* | 98.8 ± 42.5 | 259 ± 129* | 416 ± 137* | 503 ± 136* | 576 ± 93* |
P50 Inspiratory negative pressure in simulated spontaneous breathing with a bag valve mask: a bench study
F. Duprez1, T. Bonus1, G. Cuvelier2, S. Mashayekhi1, S. Ollieuz1, G. Reychler3
1Epicura, Hornu, Belgium; 2Condorcet, Tournai, Belgium; 3UCL, Bruxelles, Belgium
P51 Evaluation of inspiratory negative pressure in simulated spontaneous breathing with a bag valve mask and intubate tube: a bench study
T. Bonus1, F. Duprez1, G. Cuvelier2, S. Mashayekhi1, S. Ollieuz1, G. Reychler3
1Epicura, Hornu, Belgium; 2Condorcet, Tournai, Belgium; 3UCL, Bruxelles, Belgium
P52 Withdrawn
P53 Endothracheal tube cuff pressure assessment: anesthesiologists self–evaluation versus pressure manometer measurement
I. Kuchyn, K. Bielka, A. Sergienko
Institute of Postgraduate Education Bogomolets National Medical University, Kyiv, Ukraine
P54 Evaluation of endotracheal cuff pressure on tracheal mucosal pressure
H. Jones1, C. Day2
1Plymouth hospitals NHS Trust, Plymouth, UK; 2Royal Devon and Exeter Hospital, Exeter, UK
P55 Relation between risk of tracheal tube displacement and postural change of pretracheal tissue depth measured by ultrasound
S. C. Park, S. R. Yeom
Pusan National University Hospital, Busan, South Korea
P56 Safety and efficacy of overnight intubation compared to tracheostomy for postoperative airway management in head and neck cancer patients undergoing surgery
S. N. Myatra, S. Gupta, V. Rajnala, J. Divatia
Tata Memorial Hospital, Mumbai, India
P57 Prognosis of early tracheostomy a patients with severe head trauma (tces)
J. Villalobos Silva1, O. Aguilera Olvera1, R. Cavazos Schulte1, M. Castañeda Bermudez1, L. Pariente Zorrilla1, H. Lopez Ferretis1, K. Trejo García2
1Hospital General “Norberto Treviño”, CD. Victoria, Mexico; 2Hospital Infantil de Tamaulipas, Cd. Victoria, Mexico
P58 Withdrawn
P59 Percutaneous vs surgical tracheostomy: an incidence rate of stoma infection in the neurosurgery ICU of the single tertiary level hospital
N. Balciuniene, J. Ramsaite, O. Kriukelyte, A. Krikscionaitiene, T. Tamosuitis
Lithuanian University of Health Sciences, Kaunas, Lithuania
P60 Occurrence of ventilator associated pneumonia using tracheostomy tubes with subglottic secretion drainage
P. Terragni 1, L. Brazzi2, D. Falco2, L. Pistidda1, G. Magni3, L. Bartoletti2, L. Mascia3, C. Filippini2, V. Ranieri3
1University of Sassari, Sassari, Italy; 2Città della Salute e della Scienza Torino, Torino, Italy; 3Sapienza University of Rome Policlinico Umberto I Hospital, Roma, Italy
P61 Withdrawn
P62 Withdrawn
P63 The effect of sepsis in the outcome of spontaneous breathing trial
A. Kyriakoudi, N. Rovina, O. Koltsida, E. Konstantellou, M. Kardara, E. Kostakou, G. Gavriilidis, I. Vasileiadis, N. Koulouris, A. Koutsoukou
ICU, 1st Department of Pulmonary Medicine, “Sotiria” Hospital, Athens Medical School, Athens, Greece
P64 Dysphagia management in Dutch intensive care units: a nationwide postal survey
W. Van Snippenburg1, A. Kröner1, M. Flim1, M. Buise2, R. Hemler1, P. Spronk1
1Gelre Hospitals Apeldoorn, Apeldoorn, Netherlands; 2Catharina Hospital Eindhoven, Eindhoven, Netherlands
P65 The respiratory pressure – abdominal volume curve in a porcine model
A. Regli1, B. Noffsinger2, B. De Keulenaer1, B. Singh2, L. Hockings3, P. Van Heerden4
1Fiona Stanley Hospital, Perth, Australia; 2SCGH, Perth, Australia; 3The Alfred Hospital, Melbourne, Australia; 4Hadassah University Hospital, Jerusalem, Israel
P66 Distribution of tidal ventilation in potential lung donors: a pilot observational study
C. Spina1, A. Bronco2, F. Magni2, C. Di Giambattista1, A. Vargiolu2, G. Bellani1, G. Foti1, G. Citerio1
1University of Milano Bicocca, Monza, Italy; 2San Gerardo Hospital, Monza, Italy
P67 Pixel-level pressure-volume curves predict lung recruitability: pilot study on electrical impedance tomography (EIT) in acute respiratory failure (ARF) patients
G. Scaramuzzo1, S. Spadaro1, A. D. Waldmann2, S. H. Böhm2, R. Ragazzi1, C. A. Volta1
1University of Ferrara, Ferrara, Italy; 2Swisstom AG, Landquart, Switzerland
P68 Regional distribution of alveolar collapse and overdistension assessed by electrical impedance tomography in ARDS patients
S. J. Heines, U. Strauch, M. C. Van de Poll, P. M. Roekaerts, D. C. Bergmans
University Hospital Maastricht, Maastricht, Netherlands
P69 A calibration technique for the estimation of lung volumes in non intubated subjects by electrical impedance tomography
S. Sosio, S. Gatti, E. Maffezzini, V. Punzi, A. Asta, G. Foti, G. Bellani
University of Milano Bicocca, Milan, Italy
P70 Low frequency forced oscillation technique in lung recruitment maneuver monitoring
J. Glapinski 1, J. Mroczka1, A. Nestorowicz2, A. Fijalkowska-Nestorowicz2
1Wroclaw University of Science and Technology, Wrocław, Poland; 2Lublin Medical Univesity, Lublin, Poland
P71 Evaluation of ventilation-associated lung injury, respiratory mechanics and work of breathing by tracheal and esophageal pressure monitoring in pressure support ventilation
A. I Yaroshetskiy1, N. A. Rezepov2, I. A. Mandel3, B. R. Gelfand1
1Pirogov Russian National Research Medical University, Moscow, Russia; 2City Hospital#67, Moscow, Russia; 3Federal research and clinical center for special methods of healthcare and medical technology of FMBA, Moscow, Russia
P72 The effect of respiratory circuit system on development of ventilator associated pneumonia
E. Ozen, E. Karakoc, A. Ayyildiz, S. Kara, S. Ekemen, B. Buyukkidan Yelken
Eskisehir Osmangazi Uni. Faculty of Medicine, Eskisehir, Turkey
P73 Comparison of minute ventilation to respiratory rate measurements in the post-operative period
W. Saasouh1, J. Freeman2, A. Turan1
1Cleveland Clinic Foundation, Cleveland, OH, USA; 2Respiratory Motion, Inc, Waltham, MA, USA
P74 Ventilatory weaning failure of cardiac origin and the variation of hemoglobin and protidemia
Z. Hajjej, W. Sellami, M. Bousselmi, W. Samoud, H. Gharsallah, I. Labbene, M. Ferjani
Military Hospital of Tunis, Tunis, Tunisia
P75 Diaphragm dysfunction in intensive care unit: prevalence and effects of the non invasive ventilation
L. Vetrugno1, F. Barbariol1, F. Forfori2, I. Regeni1, G. Della Rocca1
1University-Hospital, Udine, Italy; 2University-Hospital of Pisa, Pisa Italy
P76 Reliability of diaphragm neuromuscular efficiency index in mechanically ventilated ICU patients
D. Jansen1, A. Jonkman2, J. Doorduin1, L. Roesthuis1, J. Van der Hoeven1, L. Heunks2
1Radboudumc, Nijmegen, Netherlands; 2VU Medical Center, Amsterdam, Netherlands
P77 Surface electromyography compared to ultrasound for the assessment of diaphragm activity
S. Arrigoni Marocco1, M. Bottiroli1, R. Pinciroli1, V. Galanti1, A. Calini1, M. Gagliardone1, G. Bellani2, R. Fumagalli1
1Milano Niguarda, Milano, Italy; 2Ospedale San Gerardo, Monza, Italy
P78 Evaluation of diaphragmatic thickness with ultrasound and computed tomography in mechanically ventilated patients: a prospective observational study
S. Gatti1, C. Abbruzzese2, D. Ippolito3, V. L. Sala4, V. Meroni4, A. Bronco4, G. Foti5, G. Bellani5
1University of Milano-Bicocca, Milano, Italy; 2Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 3San Gerardo Hospital, Monza, Italy; 4Hospital San Gerardo, Monza, Italy; 5University of Milano-Bicocca, San Gerardo Hospital, Monza, Italy
P79 Ventilator induced diaphragmatic dysfunction during spontaneous breathing trials assessed by ultrasonography and its impact on weaning outcome
M. Elbanna, Y. Nassar, A. Abdelmohsen, M. Yahia
Cairo University, Giza, Egypt
P80 A combined ultrasound approach to weaning from mechanical ventilation: preliminary results
S. Mongodi1, F. Mojoli1, G. Via1, G. Tavazzi1, F. Fava1, M. Pozzi1, G. A. Iotti1, B. Bouhemad2
1Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy; 2CHU Dijon, Dijon, France
P81 Respiratory work of breathing during CPAP trial on weaning from mechanical ventilation
F. Ruiz-Ferron1, J. Serrano Simón2, M. Gordillo-Resina1, V. Chica-Saez1, M. Ruiz Garcia1, R. Vela-Colmenero1, M. Redondo-Orts1
1Complejo hospitalario de Jaen, Jaen, Spain; 2Hospital Reina Sofía, Cordoba, Spain
P82 Ultrasound assessment of lung edema correlates with lung injury severity in patients with acute respiratory distress syndrome
C. Gontijo-Coutinho, T. Ozahata, P. Nocera, D. Franci, T. Santos, M. Carvalho-Filho
Unicamp, Campinas, Brazil
Survivors (n = 27) | Non-survivors (n = 30) | Total (N = 57) | |
---|---|---|---|
Age | 41.9 ± 16.6 | 51.3 ± 15.6 | 46.8 ± 16.6 |
Female | 12 | 9 | 21 |
Male | 15 | 21 | 36 |
ARDS severity | |||
Mild | 7 | 7 | 14 |
Moderate | 16 | 18 | 34 |
Severe | 3 | 6 | 9 |
Clinical data | |||
Respiratory Rate (bpm) | 17.8 ± 5.0 | 17.7 ± 4.2 | 17.7 ± 4.5 |
Mean blood pressure (mmHg) | 86.3 ± 10.5 | 85.3 ± 15.6 | 85.8 ± 13.3 |
PCO2 | 47.3 ± 18.6 | 46.2 ± 16.3 | 46.7 ± 17.3 |
Plasma lactate | 1.9 ± 1.5 | 2.8 ± 3.9 | 2.4 ± 3.0 |
Severity scores | |||
SOFA | 8.26 ± 3.31 | 9.7 ± 3.7 | |
SAPS3 | 62.9 ± 13.7 | 71.97 ± 14.51 |
P83 A modified lung ultrasound score to assess aeration in infants: comparison with CT scan
O. Fochi1, S. Gatti2, M. Nacoti1, D. Signori2, A. Bronco3, D. Bonacina1, G. Bellani4, E. Bonanomi1
1Papa Giovanni XXIII Hospital, Bergamo, Italy; 2University of Milano-Bicocca, Milano, Italy; 3San Gerardo Hospital, Monza, Italy; 4Università degli studi Milano Bicocca, San Gerardo Hospital, Monza, Italy
P84 Different probes for lung ultrasound – impact on pleural length visualization
S. Mongodi1, E. Bonvecchio1, A. Stella1, E. Roldi1, A. Orlando1, M. Luperto1, B. Bouhemad2, G. A. Iotti1, F. Mojoli1
1Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy; 2CHU Dijon, Dijon, France
Probe | Linear | Phased-Array | Convex | Micro-convex |
---|---|---|---|---|
Pleural length Transv (cm) | 3.68 ± 0.31# | 3.21 ± 0.83* | 7.18 ± 1.07* | 3.97 ± 0.91# |
Pleural length Long (cm) | 1.69 ± 0.46 | 2.05 ± 0.48 | 2.02 ± 0.58 | 1.74 ± 0.45 |
Difference in pleural length Long vs. Transv | p < 0.0001 | p < 0.0001 | p < 0.0001 | p < 0.0001 |
Pleural length variance Transv | 0.10 | 0.68 | 1.14 | 0.84 |
Pleural length variance Long | 0.21 | 0.23 | 0.34 | 0.20 |
Difference of variance Long vs. Transv | P = 0.0025 | P < 0.0001 | P < 0.0001 | P < 0.0001 |
P85 Quantitative assessment of pleural effusion with ultrasound in intensive care unit
D. Trunfio1, G. Licitra2, R. Martinelli2, D. Vannini2, G. Giuliano2, L. Vetrugno3, F. Forfori2
1Univesity Hosptial, Pisa, Italy; 2Univesity anesthesia and intensive care unit, University of Pisa, PISA, Italy; 3Azienda Ospedaliero Universitaria di Udine, Udine, Italy
P86 Accurate and rapid determination of arterial oxygen saturation using photo plethysmography on the sternum
E. Näslund1, L. G. Lindberg2, I. Lund1, A. Larsson1, R. Frithiof3
1Karolinska Institutet, Stockholm, Sweden; 2Linköping University, Linköping, Sweden; 3Uppsala University, Uppsala, Sweden
P87 Comparison of non-invasive monitoring techniques during intravenous propofol-based anesthesia: respiratory volume monitoring vs. capnography
A. Nichols1, J. Freeman2, S. Pentakota1, B. Kodali1
1Brigham & Women’s Hospital, Boston, MA, USA; 2Respiratory Motion, Inc, Waltham, MA, USA
P88 Time evolution of sublingual microcirculatory changes in recreational marathon runners
A. Pranskunas1, I. Kiudulaite1, J. Simkiene1, D. Damanskyte1, Z. Pranskuniene1, J. Arstikyte1, D. Vaitkaitis1, V. Pilvinis1, M. Brazaitis2
1Lithuanian university of health sciences, Kaunas, Lithuania; 2Lithuanian Sports University, Kaunas, Lithuania, Kaunas, Lithuania
P89 Can sublingual microcirculation predict microvascular and tissue responsiveness to usual resuscitation in a porcine model of sepsis?
R. Pool1, H. Haugaa2, A. Botero3, D. Escobar4, D. Maberry1, T. Tønnessen2, B. Zuckerbraun1, M. Pinsky1, H. Gomez1
1University of Pittsburgh, Pittsburgh, PA, USA; 2Oslo University Hospital, Oslo, Norway; 3Staten Island University Hospital, New York, NY, USA; 4Bronx-Lebanon Hospital, New York, NY, USA
P90 Retrospective study over a 12-month period looking at the national early warning score as a screening tool for patients with sepsis admitted to intensive care
H. Lyons, A. Trimmings
East Sussex Healthcare, East Sussex, UK
P91 Microcirculatory daily monitoring in polytraumatic patients
R. Domizi, C. Scorcella, E. Damiani, S. Pierantozzi, S. Tondi, V. Monaldi, A. Carletti, S. Zuccari, E. Adrario, P. Pelaia, A. Donati
Università Politecnica delle Marche, Ancona, Italy
P92 Skin oxygenation and relative hemoglobin concentration measured by hyperspectral imaging based method as prognostic indicators in septic shock
S. Kazune1, A. Grabovskis2, K. Volceka2, U. Rubins2
1Hospital of Traumatology and Orthopaedics, Riga, Latvia; 2University of Latvia, Riga, Latvia
P93 Intra operator variability in visualization of microcirculation in ICU patients using sidestream dark field imaging
M. Bol, M. Suverein, T. Delnoij, R. Driessen, S. Heines, T. Delhaas, M. Vd Poll, J. Sels
MUMC, Netherlands, Netherlands
P94 Effect of two levels of mean arterial pressure on microcirculatory reserve in septic shock patients
M. Jozwiak, M. Chambaz, P. Sentenac, C. Richard, X. Monnet, J. L. Teboul
Hôpitaux universitaires Paris-Sud, Hôpital de Bicêtre, Inserm UMR S_999, Univ Paris-Sud, Le Kremlin-Bicêtre, France
P95 B-lines on chest ultrasound predicts elevated left ventricular diastolic pressures
Z. Bitar1, O. Maadarani2, R. Al Hamdan2
1Hôpitaux universitaires Paris-Sud, Hôpital de Bicêtre, Inserm UMR S_999, Univ Paris-Sud, Le Kremlin-Bicêtre, France; 2zouheir bitar, Fahahil, Kuwait
Thoracic ultrasound profile | High E/E’ | Normal E/E’ | Total |
---|---|---|---|
B- Profile | 46 | 1 | 47 |
A -profile | 4 | 10 | 14 |
total | 50 | 11 | 61 |
Variable | Value | 95% confidence interval | |
sensitivity | 0.92 | 0.812 to 0.968 | |
Specificity | 0.91 | 0.623 to 0.98 | |
Positive predictive value | 0.97 | 0.889 to 0.996 | |
Negative predictive value | 0.714 | 0.454 to 0.883 |
P96 Association of extravascular lung water (EVLW) to biometric data: a meta-analysis based on original data by the elwi-star-investigators
W. Huber1, M. Malbrain2, M. Chew3, J. Mallat3, T. Tagami4, S. Hundeshagen1, S. Wolf5
1Klinikum rechts der Isar; Technical University of Munich, Munich, Germany; 2University Hospital, Ghent, Belgium; 3Centre Hospitalier, Lens, France; 4Nagayama Hospital, Tokyo, Japan; 5Charité, Campus Virchow-Klinikum, Berlin, Germany
P97 Personalized haemodynamic monitoring: context-sensitive indexation of haemodynamic parameters – a database feasibility analysis
W. Huber, S. Mair, R. Schmid
Klinikum rechts der Isar; Technical University of Munich, Munich, Germany
Biometry | R2
| Context | R2
| Combined model | R2
| |
---|---|---|---|---|---|---|
GEDV | A, G, W, H | 0.306 | HR, Rh | 0.040 | A, G, W, H, Rh, CVC | 0.345 |
SV | A, W, H | 0.281 | HR, Rh, MV | 0.194 | A, W, H, HR, Rh, MV | 0.444 |
SVV | A | 0.014 | HR, Rh, MV | 0.225 | A, W, HR, Rh, MV | 0.244 |
EVLW | A, H | 0.039 | HR, CVC | 0.016 | A, H, HR, CVC | 0.059 |
CVP | W, H | 0.02 | MV | 0.039 | A, W, H, Rh, MV | 0.074 |
P98 Haemodynamic monitoring – awareness and clinical exposure
J. Aron1, M. Adlam1, G. Dua2
1St Georges Hospital, London, UK; 2GSTT, London, UK
P99 Forecasting tachycardia in the ICU
L. Mu1, L. Chen1, J. Yoon2, G. Clermont2, A. Dubrawski1
1Carnegie Mellon University, Pittsburgh, PA, USA; 2University of Pittsburgh, Pittsburgh, PA, USA
P100 Qt dispersion in critical illness and relationships with serum lactate
Z. Duhailib, K. Al Assas, A. Shafquat, N. Salahuddin
Zainab Al Duhailib, Riyadh, Saudi Arabia
P101 Mortality associated with tachycardia in an intensive care population
J. Donaghy, P. Morgan
East Surrey Hospital, Redhill, UK
P102 Minimally invasive cardiovascular monitoring is associated with good outcome: results of a multicentre study
L. Valeanu, M. Stefan, S. Provenchere, D. Longrois
Hopital Bichat, Paris, France
Bichat number | Total number | |
---|---|---|
Included patients | 115 (%) | 3111 (%) |
Mean Euroscore II | 3.89+/−2.36 | 3.75+/−0.5 |
Mean ECC/CC time* | 67+/−33/53+/−24 | 97+/−48/70+/−35 |
Monitoring | ||
TEE intraoperative/ICU | 42 (36)/6 (5) | 1139 (36)/250 (8) |
TTE ICU* | 110 (95) | 1327 (42) |
CO monitoring intraoperative*/ICU* | 0/3 (2.6) | 387 (15)/338 (10) |
Postoperative complications | ||
Death* | 0 | 96 (3) |
All complications confounded | 52 (45) | 1338 (43) |
ICU stay (days) | 4+/−4.8 | 4.1+/−4.8 |
P103 Pulmonary artery catheter (PAC) use is associated with improved clinical outcomes after adult cardiac surgery
A. Shaw1, M. G. Mythen2, D. Shook3, D. Hayashida4, X. Zhang4, S. H. Munson4
1Vanderbilt University Medical Center, Nashville, TN, USA; 2UCL, London, UK; 3Brigham and Womens Hospital, Boston, MA, USA; 4Boston Strategic Partners, Boston, MA, USA
P104 Management of retained guidewires: the ‘suck out technique’
A. Sawyer, M. Mariyaselvam, M. Blunt, P. Young
Queen Elizabeth Hospital, Kings Lynn, UK
Wire end above skin | Wire end below skin | |
---|---|---|
Simple removal | 100% | 0% |
Clamped removal | 100% | 10% |
Suck out removal | 100% | 90% |
P105 A comparison of left ventricular systolic function index provided by volumeview/ev1000™ and left ventricular ejection fraction by echocardiography in septic shock patients
N. Nakwan1, B. Khwannimit1, P. Checharoen2
1Division of Critical Care Medicine, Hat Yai, Thailand; 2Division of Cardiology, Prince of Songkla University, Hat Yai, Thailand
P106 Methodological issues for the determination of mean systemic filling pressure at the end of life
D. Berger1, P. Moller2, S. Bloechlinger1, A. Bloch1, S. Jakob1, J. Takala1
1Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; 2Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden
P107 Critical closing pressure in human endotoxemia and sepsis
J. M. Van den Brule, R. Stolk, E. Vinke, L. M. Van Loon, P. Pickkers, J. G. Van der Hoeven, M. Kox, C. W. Hoedemaekers
Radboud UMC, Nijmegen, Netherlands
P108 Right atrial pressure as back-pressure to venous return
P. Werner-Moller, S. Jakob, J. Takala, D. Berger
Inselspital, University Hospital of Bern, Bern, Switzerland
P109 Right ventricular-vascular coupling: a single-beat noninvasive approach in the critically ill
P. Bertini1, F. Guarracino1, D. Colosimo2, S. Gonnella1, G. Brizzi1, G. Mancino1, R. Baldassarri1, M. R. Pinsky3
1Azienda Ospedaliero Universitaria Pisana, Pisa, Italy; 2Meyer Children Hospital, Florence, Italy; 3University of Pittsburgh, Pittsburgh, PA, USA
P110 Right ventricular ejection fraction: new non volume-based method
P. Bertini, S. Gonnella, G. Brizzi, G. Mancino, D. Amitrano, F. Guarracino
Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
P111 Treatment of right heart thrombi in pulmonary embolism
T. Goslar, D. Stajer, P. Radsel
University center Ljubljana, Ljubljana, Slovenia
P112 Massive pulmonary embolism: a potential lethal complication in patients with autoimmune haemolytic anaemia
R. De Vos, N. Bussink-van Dijk
Academic hospital Maastricht, Maastricht, Netherlands
P113 Cardiac output monitoring: comparison between a non-invasive and a minimally invasive device
G. Stringari, G. Cogo, A. Devigili, M. Ceola Graziadei, E. Bresadola, P. Lubli, S. Amella, F. Marani, E. Polati, L. Gottin
AOUI Verona, Verona, Italy
Parameter | Median | 25–75 P | p |
---|---|---|---|
CIc | 2.7 | 2.4–3.0 | |
CIv | 3 | 2.6–3.5 | <0.001 |
DPc | 60 | 54.0–67.0 | |
DPv | 55 | 48.5–63.0 | <0.001 |
MAPc | 72,5 | 66,0–81,0 | |
MAPv | 76,5 | 70.0–85.0 | <0.001 |
SPc | 96,5 | 86.0–112.5 | |
SPv | 121 | 104.5–134.0 | <0.001 |
SVVc | 13,5 | 10.0–17.0 | |
SVVv | 11,5 | 9.0–16.0 | 0.0012 |
P114 Echocardiographic measurement of cardiac output through modified subcostal window: consistency analysis
L. Colinas 1, G. Hernández1, R. Vicho2, M. Serna3, A. Canabal1, R. Cuena1
1Virgen de la Salud Hospital, Madrid, Spain; 2Quironsalud Palmaplanas Hospital, Palma de Mallorca, Spain; 3Marina Salud Denia Hospital, Denia, Spain
P115 Precision of measurements with transthoracic echocardiography in critically ill patients
M. Jozwiak, J. Gimenez, J. L. Teboul, P. Mercado, F. Depret, C. Richard, X. Monnet
Hôpitaux universitaires Paris-Sud, Hôpital de Bicêtre, Inserm UMR S_999, Univ Paris-Sud, Le Kremlin-Bicêtre, France
P116 Withdrawn
P117 The contribution of (pvco2-paco2)/(cao2-cvo2) ratio level as an indicator of anaerobic metabolism variation in patients with septic shock
Z. Hajjej, W. Sellami, K. Sassi, H. Gharsallah, I. Labbene, M. Ferjani
Military Hospital of Tunis, Tunis, Tunisia
P118 Accuracy and precision of ScvO2 measured with the CeVOX-device: a prospectice study in patients with a wide variation of ScvO2-values
A. Herner, R. Schmid, W. Huber
Klinikum rechts der Isar; Technical University of Munich, Munich, Germany
P119 Role of veno-arterial co2 gap in patients with sepsis and its correlation with other markers of hyppoperfusion
N. Abded, Y. Nassar, M. Elghonemi, A. Monir
University of Cairo, Cairo, Egypt
P120 Tissue perfusion marker responses to fluid resuscitation? search for an ideal marker
J. Nikhilesh, T. Apurv
CHL Hospitals, Indore, India
P121 Relationship between initial lactate and the need of ICU-specific interventions in patients with suspected infection presenting to the emergency department
A. U. Uber, A. Grossestreuer, A. Moskowitz, P. Patel, M. J. Holmberg, M. W. Donnino
Beth Israel Deaconess Medical Center, Boston, MA, USA
P122 Agreement between capillary and venous poct lactate in emergency department patients
CA Graham1, K Hung1, R Lo1, LY Leung1, KH Lee2, CY Yeung1, SY Chan1
1The Chinese University of Hong Kong, Hong Kong, Hong Kong; 2 Prince of Wales Hospital, Hong Kong, Hong Kong
P123 The evaluation of peripheral chemoreflex sensitivity in patients with chronic heart failure
N Trembach, I Zabolotskikh
Kuban State Medical University, Krasnodar, Russia
P124 Cerebral blood flow autoregulation in ischemic heart failure
J Caldas1, R Panerai2, L Camara1, G Ferreira1, J Almeida1, G Queiroz de Oliveira1, J Jardim1, E Bor-Seng-Shu1, M Lima1, R Nogueira1, F Jatene1, S Zeferino1, F Galas1, T Robinson 2, LA Hajjar1
1University of Sao Paulo, Sao Paulo, Brazil; 2University of Leicester, Leicester, United Kingdom
P125 Cerebral hemodynamic in high-risk cardiac patients undergoing cardiac surgery with cardiopulmonary bypass: the role of intra-aortic balloon
J Caldas1, R Panerai2, G Ferreira1, L Camara1, S Zeferino1, J Jardim1, E Bor-Seng-Shu1, M Oliveira1, R Norgueira1, R Groehs1, L Ferreira-Santos1, F Galas1, G Oliveira1, J Almeida1, T Robinson2, F Jatene1, L Hajjar1
1University of Sao Paulo, Sao Paulo, Brazil; 2University of Leicester, Leicester, United Kingdom
P126 Effect of preoperative intra-aortic balloon pump on outcomes following cardiac surgery in high-risk patients: a prospective randomized clinical trial
G Ferreira, J Ribeiro, F Galas, F Gaiotto, L Lisboa, J Fukushima, S Rizk, J Almeida, F Jatene, E Osawa, R Franco, R Kalil, L Hajjar
University of Sao Paulo, Brazi, Sao Paulo, Brazil
P127 Clinical evaluation of the volemic status in critically ill non-septic cardiac patients- the role of central venous pressure
M Chlabicz, B Sobkowicz, K Kaminski, R Kazimierczyk, W Musial, A Tycińska
Medical University of Bialystok, Bialystok, Poland
P128 Comparation between invasive and non invasive haemodynamic volume predictors in surgical patients on mechanical ventilation with i and ii degree abdominal hypertension-preliminary study
M Siranovic, A Gopcevic, ZG Gavranovic, AH Horvat, H Krolo, B Rode, L Videc
Clinical hospital center, Zagreb, Croatia
P129 Ultrasonic stroke volume variation by passive leg raising and fluid responsiveness in medical icu patients
A Trifi, S Abdellatif, K Ben Ismail, A Bouattour, F Daly, R Nasri, S Ben Lakhal
University hospital center of La Rabta, Tunis, Tunisia
P130 Accuracy of the passing leg raising test in patients with intra-abdominal hypertension
A Beurton1, JL Teboul2, V Girotto2, L Galarza2, C Richard2, X Monnet2
1Hôpital de Bicêtre, Le Kremlin Bicêtre, France; 2Hôpital de Bicêtre, Hôpitaux universitaires Paris-Sud, Assistance publique – Hôpitaux de Paris, Le kremlin bicêtre, France
P131 The accuracy of the perfusion index to detect the variation of the cardiac index
A Beurton, JL Teboul, V Girotto, L Galarza, C Richard, X Monnet
Hôpital de Bicêtre, Le Kremlin Bicêtre, France
P132 Can carotid and femoral doppler assess the effects of passive leg raising?
V Girotto1, JL Teboul2, A Beurton2, L Galarza2, T Guedj3, X Monnet2
1Hôpital de Bicêtre, Le Kremlin-Bicêtre, France; 2Service de réanimation médicale, Inserm UMR S_999, Université Paris-Sud, Le Kremlin-Bicêtre, France; 3Hôpital de Bicêtre, Hôpitaux universitaires Paris-Sud, Assistance publique – Hôpitaux de Paris, Le Kremlin-Bicêtre, France
P133 Could bioreactance assess the effects of passive leg raising in critically ill patients?
L Galarza, P Mercado, JL Teboul, V Girotto, A Beurton, C Richard, X Monnet
Hôpital de Bicêtre, Le Kremlin-Bicêtre, France
P134 Reliability of lung ultrasound and inferior vena cava collapsibility index in volume status estimation in ICU patients during early postoperative period
M Karaman Iliæ1, L Sakic1, V NN1, L Stojcic2
1Clinical Hospital Sveti Duh, Faculty of Medicine, University of Osijek, Zagreb, Croatia; 2University of Zagreb, School of Medicine, Zagreb, Croatia
P135 Predicting fluid responsiveness by using combined end-expiratory and end-inspiratory occlusion tests with echocardiography
M Jozwiak, F Depret, JL Teboul, J Alphonsine, C Lai, C Richard, X Monnet
Hôpitaux universitaires Paris-Sud, Hôpital de Bicêtre, Inserm UMR S_999, Univ Paris-Sud, Le Kremlin-Bicêtre, France
P136 Changes in ftc with peep titration, but not absolute value of ftc, predicts fluid responsiveness in patient with septic shock
N Tapanwong, P Chuntupama, P Wacharasint
Phramongkutklao hospital, Bangkok, Thailand
P137 Adjustment of stroke volume variation svv to biometric data and other contexts: a database analysis with an independent validation study
W Huber, J Hoellthaler, T Lahmer, R Schmid
Klinikum rechts der Isar; Technical University of Munich, Munich, Germany
P138 Stroke volume guided resuscitation in severe sepsis and septic shock decreases time on pressors and ICU stay
H Latham, CD Bengtson, L Satterwhite, M Stites, SQ Simpson
University of Kansas Medical Center, Kansas City, Kansas, United States
P139 Stroke volume guided resuscitation in severe sepsis and septic shock decreases need for mechanical ventilation
H Latham, CD Bengtson, L Satterwhite, M Stites, SQ Simpson
University of Kansas Medical Center, Kansas City, Kansas, United States
P140 Measurement of the inferior vena cava as a method of evaluating the fluid balance of mechanically ventilated patients
T Skladzien, M Cicio, J Garlicki, W Serednicki, J Wordliczek
Szpital Uniwersytecki, Cracow, Poland
P141 Negative fluid balance is associated with a reduction in airway driving pressure in critically ill patients with fluid overload
P Vargas, A Salazar, P Mercado, M Espinoza, J Graf
Clinica Alemana, Santiago, Chile
Age | 62 ± 15 |
APACHE II | 20.4 ± 6.4 |
SOFA | 8.7 ± 3.6 |
Septic shock (%) | 78 |
Pneumonia (%) | 33 |
PaO2/FiO2 | 250 ± 77 |
PEEP (cmH2O) | 8.7 ± 3.4 |
Tidal volume (ml/Kg PBW) | 6.3 ± 1.2 |
P142 Positive cumulative fluid balance during the first week of acute respiratory distress syndrome as a predictor of 28-day mortality
N Kongpolprom, N Sanguanwong
Chulalongkorn University, Bangkok, Thailand
Cut off values of 7-day fluid balance | Odds ratio | 95% CI | p value |
---|---|---|---|
− 5000 ml | 2.25 | 0.54 to 9.28 | 0.264 |
− 1000 ml | 2.95 | 1.24 to 7.02 | 0.014 |
0 ml | 2.95 | 1.31 to 6.65 | 0.009 |
+1000 ml | 3.99 | 1.95 to 8.19 | <0.001 |
+5000 ml | 3.90 | 2.10 to 7.24 | <0.001 |
+10000 ml | 4.98 | 2.21 to 11.22 | <0.001 |
+15000 ml | 10.58 | 1.39 to 80.64 | 0.023 |
P143 The association of intravenous fluid administration on patient outcomes in critical care
S Jonnada1, C Gerrard2, N Jones2
1University of Cambridge, Cambridge, United Kingdom; 2Papworth Hospital, Papworth, United Kingdom
P144 Restrictive fluid therapy in septic shock – is peripheral noradrenaline the answer?
T Morley, PT Thorburn, A Trimmings
East Sussex Healthcare NHS Trust, Eastbourne, United Kingdom
P145 The impact of perioperative fluid balance on postoperative complications
T Musaeva, I Zabolotskikh
Kuban State Medical University, Krasnodar, Russia
P146 Early protocolized post-resuscitation fluid overload removal is safe
A Salazar, P Vargas, P Mercado, M Espinoza, J Graf
Clinica Alermana, Santiago, Chile
Baseline | 48 h | p | |
---|---|---|---|
BUN (mg/dL) | 29.5 ± 18.9 | 31.4 ± 14.3 | 0.59 |
Creatinine (mg/dL) | 1.10 ± 0.59 | 0.99 ± 0.41 | 0.09 |
Na (mEq/L) | 142 ± 4 | 139 ± 3 | <0.01 |
K (mEq/L) | 4.2 ± 0.5 | 4.4 ± 0.7 | 0.04 |
HCO3 (mEq/L) | 24.3 ± 2.8 | 27.6 ± 3.1 | <0.01 |
CO (L/min) | 6.5 ± 2.5 | 5.7 ± 1.3 | <0.01 |
SvcO2 (%) | 78 ± 7 | 76 ± 5 | <0.01 |
Lactate (mM/L) | 1.6 ± 0.6 | 1.4 ± 0.4 | 0.04 |
va pCO2 gap (mmHg) | 4.6 ± 1.9 | 5.0 ± 3.7 | 0.70 |
P147 The impact of resuscitation fluid bag size availability on the volume of fluid administration in the ICU (the tiring study)
S Horst1, M Lipcsey1, R Kawati1, A Pikwer2, J Rasmusson3, M Castegren4
1Department of Surgical Sciences, Uppsala, Sweden,2Eskilstuna County Hospital, Eskilstuna, Sweden,3Gävle County Hospital, Gävle, Sweden,4Karolinska University Hospital Solna, Stockholm, Sweden
P148 Characteristics of patients with elevated troponin I level and prompt coronary arteries
A Shilova, A Yafarova, M Gilyarov
Moscow Clinical City Hospital #1 named after N. Pirogov, Moscow, Russia
P149 Perioperative effects of remifentanil vs fentanyl on cardiovascular and humoral response in elderly patients undergoing total gastrectomy
DL Loncar Stojiljkovic
Special Gynecological Hospital, Jevremova, 11000, Serbia
P150 Clevidipine versus sodium nitroprusside as adjunct therapy to esmolol in aortic dissection
A Ulici, S Reidt, T Lam, J Jancik
Hennepin County Medical Center, Minneapolis, MN, United States
P151 Continuous infusion of furosemide versus intermittent boluses in acute decompensated heart failure: non-invasive evaluation of the effect on thoracic fluid content
D Ragab, K Taema, W Farouk, M Saad
Cairo University, Cairo, Egypt
P152 In vitro ubiquinol increases cellular oxygen consumption in peripheral blood mononuclear cells from patients with metabolic stress
X Liu, MJ Holmberg, A Uber, S Montissol, M Donnino, LW Andersen
Beth Israel Deaconess Medical Center, Boston, MA, United States
P153 Lazaroid (u-74389 g) prevents lung ischemia-reperfusion injury caused by thoracoabdominal aortic occlusion
F Perlikos1, M Lagiou2, A Papalois3, C Kroupis2, I Toumpoulis4
1Evangelismos Hospital, Athens, Greece; 2Attikon Hospital, Athens, Greece; 3ELPEN Research and Experimental Center, Athens, Greece; 4Department of Cardiac Surgery, Attikon Hospital, Athens, Greece
P154 Nitric oxide in cardiac surgery. A meta-analysis of randomized trials
E Osawa1, D Carter1, S Sardo1, J Almeida1, F Galas1, S Rizk1, R Franco1, L Hajjar1, G Landoni2
1Heart Institute, Sao Paulo, Brazil; 2San Raffaele, Milan, Italy
P155 Preoperative beta-blocker & vasodilator combined with neuraxial block increase risk of perioperative cardiac complication in patients admitting to the general surgical ICU
S Kongsayreepong, R Sungsiri, P Wongsripunetit
Siriraj Hospital, Mahidol University, Bangkok, Thailand
P156 Levamisole, a cocaine adulterant, potentiates the contractile response to endothelin-1 in rabbit carotid artery
P Marchio, S Guerra-Ojeda, M Gimeno-Raga, MD Mauricio, SL Valles, C Aldasoro, A Jorda, M Aldasoro, JM Vila
University of Valencia, Valencia, Spain
P157 Effect of volume vs. vasoconstriction on regional oxygen saturation during hemodynamic management
UB Borg, AM Neitenbach
Medtronic, Boulder, CO, United States
CrSO2 (%) | RrSO2 (%) | MAP (mm Hg) | |
---|---|---|---|
Baseline values | 59.9 ± 5.4 | 62.8 ± 8.6 | 74.8 ± 10.7 |
Hypovolemia | 44.8 ± 5.8 | 57.0 ± 9.6 | 38.3 ± 8.7 |
After blood infusion | 56.1 ± 6.6 | 63.4 ± 8.2 | 75.6 ± 8.4 |
After NE | 59.4 ± 6.4 | 57.4 ± 4.9 | 90.2 ± 8.0 |
P158 Dynamic arterial elastance reflects pressure-flow uncoupling in an experimental endotoxic septic shock
M García1, P Guijo González2, M Gracia Romero2, P Saludes Orduña2, A Gil Cano2, A Rhodes1, RM Grounds1, M Cecconi1
1St. George’s Healthcare NHS Trust and St George’s University of London, London, United Kingdom,2Hospital SAS de Jerez, Jerez de la Frontera, Spain
P159 Validation of hypotension probability algorithm on university of California, Irvine surgical patients
C Lee1, F Hatib1, Z Jian1, J Rinehart2, J De Los Santos2, C Canales2, M Cannesson3
1Edwards Lifesciences, Irvine, CA, United States,2UC Irvine School of Medicine, Irvine, CA, United States,3UCLA David Geffen School of Medicine, CA, Los Angeles, United States
Threshold | Time to Event (min) | P(↓BP) at Threshold Crossing (%) | MAP at Threshold Crossing (mmHg) |
---|---|---|---|
P(↓BP) ≥ 51 | 19.7 [8–62.7] | 61 [56–91] | 72.7 [68–76.2] |
P(↓BP) = 100 | 0 [0–0] | 100 [100–100] | 59.2 [55.5–61.9] |
P160 Pre-emptive protocol based on hypotension probability indicator: preliminary clinical results
MI Monge García
Hospital SAS de Jerez, Jerez de la Frontera, Spain
P161 Prediction of hypotension in porcine model
F Hatib1, Z Jian1, T Scheeren2
1Edwards Lifesciences, Irvine, CA, United States; 2University Medical Center Groningen, Groningen, Netherlands
P162 Prevalence of hypotension and prediction of hypotension in intensive care unit
Z Jian1, F Hatib1, M Pinsky2
1Edwards Lifesciences, Irvine, CA, United States; 2University of Pittsburgh, Pittsburgh, PA, United States
P163 A novel method of ultrasonic assessment of bilateral radial artery stiffness characteristics
V Chantziara1, A Vassi1, G Michaloudis1, E Sanidas2, S Golemati3
1Saint Savvas Hospital, Athens, Greece; 2Cardiology Dep, Laiko General Hospital, Athens, Greece; 3Medical School, National Kapodistrian University of Athens, Athens, Greece
Left side | Right side |
p-value | |
---|---|---|---|
D
d
, mm | 1.66 ± 0.54 | 1.63 ± 0.67 | 0.94 |
D
s
, mm | 1.73 ± 0.53 | 1.72 ± 0.69 | 0.96 |
\( \varepsilon \), % | 5.04 ± 3.67 | 5.68 ± 3.94 | 0.78 |
DC, kPa−1*10−3
| 21.90 ± 17.88 | 19.74 ± 11.24 | 0.81 |
CC, m2/kPa*10−3
| 5.60E-6 ± 4.56E-6 | 6.06E-6 ± 6.43E-6 | 0.89 |
E
P
, kPa | 87.18 ± 76.28 | 72.13 ± 57.31 | 0.71 |
P164 Non-invasive measurement of arterial flow velocity in the dorsalis pedis artery under control and septic conditions
RM Bateman
University of Western Ontario, London, Canada
P165 Predictive value of measuring brachial artery reactivity in septic patients
A Mokhtar1, W Omar1, K Abdel Aziz2, H El Azizy2
1Salam International Hospital, Cairo, Egypt,2Cairo University Hospital, Cairo, Egypt
P166 (How) do patients with different shock etiologies differ in clinical presentation at arrival to the emergency department?
DL Lykke Nielsen, JG Holler, A Lassen
Odense University Hospital, Odense C, Denmark
P167 Intraosseous administration of adrenaline does not impair uptake of a subsequent injection in hypovolemic shock
M Eriksson1, G Strandberg1, M Lipcsey1, A Larsson2
1Surgical Sciences, Uppsala, Sweden; 2Medical Sciences, Uppsala, Sweden
P168 Vasopressin versus norepinephrine for the management of septic shock in cancer patients (vancs ii)
C Capoletto, J Almeida, G Ferreira, J Fukushima, R Nakamura, S Risk, E Osawa, C Park, G Oliveira, F Galas, R Franco, L Hajjar
Cancer Institute of the University of Sao Paulo, Sao Paulo, Brazil
P169 Outcomes in septic shock patients requiring vasopressin
F Dias, N D’Arrigo, F Fortuna, S Redaelli, L Zerman, L Becker
Hospital Pompeia, Caxias do Sul, Brazil
Variable | Group 1 | Group 2 | p value |
---|---|---|---|
SAPS 3 | 74.1 | 67.1 | 0.004 |
SAPS 3 SMR LA | 71 | 60 | 0.005 |
SOFA admission | 9.7 | 8.4 | 0.003 |
ICU mortality | 77.8 | 35.8 | <0.001 |