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Current Cardiology Reports
Erschienen in:

02.05.2023 | Regenerative Medicine (SM Wu, Section Editor)

3D Printing Approaches to Engineer Cardiac Tissue

verfasst von: Ting-Yu Lu, Yi Xiang, Min Tang, Shaochen Chen

Erschienen in: Current Cardiology Reports | Ausgabe 6/2023

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Abstract

Purpose of Review

Bioengineering of functional cardiac tissue composed of primary cardiomyocytes has great potential for myocardial regeneration and in vitro tissue modeling. 3D bioprinting was developed to create cardiac tissue in hydrogels that can mimic the structural, physiological, and functional features of native myocardium. Through a detailed review of the 3D printing technologies and bioink materials used in the creation of a heart tissue, this article discusses the potential of engineered heart tissues in biomedical applications.

Recent Findings

In this review, we discussed the recent progress in 3D bioprinting strategies for cardiac tissue engineering, including bioink and 3D bioprinting methods as well as examples of engineered cardiac tissue such as in vitro cardiac models and vascular channels.

Summary

3D printing is a powerful tool for creating in vitro cardiac tissues that are structurally and functionally similar to real tissues. The use of human-induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) enables the generation of patient-specific tissues. These tissues have the potential to be used for regenerative therapies, disease modeling, and drug testing.
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Metadaten
Titel
3D Printing Approaches to Engineer Cardiac Tissue
verfasst von
Ting-Yu Lu
Yi Xiang
Min Tang
Shaochen Chen
Publikationsdatum
02.05.2023
Verlag
Springer US
Erschienen in
Current Cardiology Reports / Ausgabe 6/2023
Print ISSN: 1523-3782
Elektronische ISSN: 1534-3170
DOI
https://doi.org/10.1007/s11886-023-01881-y

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