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Erschienen in: Nuclear Medicine and Molecular Imaging 4/2017

Open Access 16.08.2016 | Interesting Image

68Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma

verfasst von: Bart de Keizer, Gerard C. Krijger, F. Tessa Ververs, Robert J. J. van Es, Remco de Bree, Stefan Willems

Erschienen in: Nuclear Medicine and Molecular Imaging | Ausgabe 4/2017

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Abstract

A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a 68Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, 68Ga-PSMA PET-CT might be a promising imaging modality for this malignancy.

Compliance with Ethical Standards

Conflict of interest

Bart de Keizer, Gerard Krijger, Tessa Ververs, Robert van Es, Remco de Bree and Stefan Willems declare that they have no conflict of interest.

Ethical statement

The study was approved by an institutional review board or equivalent and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. All subjects in the study gave written informed consent or the institutional review board waived the need to obtain informed consent.
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
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Metadaten
Titel
68Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
verfasst von
Bart de Keizer
Gerard C. Krijger
F. Tessa Ververs
Robert J. J. van Es
Remco de Bree
Stefan Willems
Publikationsdatum
16.08.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Nuclear Medicine and Molecular Imaging / Ausgabe 4/2017
Print ISSN: 1869-3474
Elektronische ISSN: 1869-3482
DOI
https://doi.org/10.1007/s13139-016-0445-6

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