A before-after study of hospital use in two frail populations receiving different home-based services over the same time in Vancouver, Canada

Frailty is a “multidimensional syndrome of loss of reserves (energy, physical ability, cognition, health) that gives rise to vulnerability” (p. 489 [1]) and is highly associated with older age [2]. It is estimated 5.6% of the general population is homebound as a result of frailty [3] and primary care medical health services are poorly designed for these individuals. The standard office visit lasts 10-15 min, examination tables are often inaccessible to those with mobility problems, and many frail individuals are dependent on others to get to appointments. In addition, the number of family physicians making house calls is declining over time [4].

Frail community-dwelling older people are at greater risk of hospital emergency department (ED) visits and hospital admissions [5, 6]. One Canadian study reported the 2004/5 prevalence of ED visits was 41.7% among those over 85 years [7]. Ironically, while frail older people are most likely to use acute hospital care (ED visits and hospital admissions), they are least likely to benefit [8, 9] and most likely to experience harm from such services [10]. Research has further demonstrated an inverse association between ED use and access to primary care among older adults [11, 12].

Home-based primary care (HBPC) refers to integrated home-based care for medical, nursing, rehabilitative, and palliative care needs. A number of home-based primary care programs have developed throughout North America [13‐15]. However, such programs are still uncommon, there are relatively few evaluative studies on these programs, and generalizability is limited by the variation in types of services offered [14], policy context, and the jurisdiction in which they are delivered [13, 16‐18].

Home care (HC) is defined as clinical case management, direct nursing care, allied health support and home support as needed [19] with receipt of usual primary medical care as a separate service. For the purposes of this study, HC refers to the need and receipt of regular home support services. There is growing awareness in Canada of the importance of HC as a strategy for strengthening the health system’s capacity to meet the needs of the aging population [20, 21] and HC has become a major focus of recent federal government funding [22, 23]. A major challenge of HC has been its’ separate evolution from primary medical care such that clinical records of HC providers and family physicians remain separate, and communication between these services is often episodic and crisis driven [24].

This study’s first objective was to assess the influence of a multidisciplinary HBPC program in Vancouver, Canada on acute hospital use by examining rates of ED visits and hospital admissions before and after receipt of this service. The second objective was to examine these outcomes in a selection of community-dwelling individuals who started HC over the same time period, and continued to receive usual primary care.

There were 246 individuals in the HBPC group and 492 in the HC group. Both groups had a similar distribution of sex, CHESS and MAPLe scores, and living alone. One third of the HBPC and one quarter of the HC group were over 90 years of age (33.3% versus 25.4%, p = 0.024) (Table 2).

In the period before the start of HBPC, baseline ED visit and hospital admission rates (95% Confidence Interval (CI)) were 4.1 (3.8, 4.4) per 1000 PD and 2.3 (2.1, 2.5) per 1000 PD respectively. In the period before the start of HC, baseline ED visit and hospital admission rates (95% CI) for this cohort were 3.0 (2.8, 3.2) per 1000 PD and 1.3 (1.2, 1.4) per 1000 PD respectively (Table 2). Differences in baseline ED visit and hospital admission rates between groups were statistically significant (p < .0001) (Table 2). At baseline, HBPC recipients also presented to the ED with significantly higher acuity compared to HC recipients (as measured by a higher proportion of CTAS 1 to 3 at the time of presentation to the ED (p = 0.008)) (Table 2) and spent a greater number of days in hospital per 1000 PD (95% CI), 41.8 (40.7, 42.8) versus 18.6 (18.2, 19.1) (p < .0001) (Table 2).

In the period after receipt of HBPC, there was a non-significant decrease in ED visit rates (95% CI) from 4.1 (3.8, 4.4) visits per 1000 PD to 3.7 (3.3, 4.1) visits per 1000 PD (p = 0.332) and hospital admission rates (95% CI) from 2.3 (2.1, 2.5) admissions per 1000 PD to 2.2 (1.9, 2.5) admissions per 1000 PD (p = 0.726) (Table 3). Rates of days spent in hospital (95% CI) also had a non-significant decrease from 41.8 (40.7, 42.8) days per 1000 PD to 39.5 (38.1, 40.8) days per 1000 PD (p = 0.719) in the period after HBPC program enrollment (Table 3). Adjusted IRRs and 95% CI post receipt of HBPC were 0.91 (0.72, 1.15) for ED visit rates and 0.99 (0.76, 1.27) for hospital admissions (Table 4).

In the period after receipt of HC, ED visit rates (95% CI) for this group increased significantly from 3.0 (2.8, 3.2) visits per 1000 PD before to 4.0 (3.7, 4.3) visits per 1000 PD after (p < .0001) and hospital admission rates (95% CI) increased from 1.3 (1.2, 1.4) admissions per 1000 PD to 1.9 (1.7, 2.1) admissions per 1000 PD (p < .0001). Post receipt of HC, the rate for days spent in hospital increased from 18.6 (18.2, 19.1) days per 1000 PD to 20.9 (20.3, 21.6) days per 1000 PD (p = 0.303) (Table 3). Adjusted IRRs (95% CI) in the period post receipt of HC were 1.34 (1.15, 1.56) for ED visit rates and 1.46 (1.22, 1.74) for hospital admission rates (Table 4).

In the adjusted models, male sex, higher CHESS score and death were almost all positively associated with ED visits and hospital admission rates for both groups (Table 3). Older age was inversely associated with ED visit rates in both groups and hospital admission rates for HC recipients only (Table 4). There were no differences in our results when we conducted sensitivity analyses to explore a potential effect due to the larger size that comprised the HC cohort.

At study end, a similar proportion from each group was admitted to a nursing home 0.22 (95% CI 0.17, 0.28) of HBPC (N = 54) and 0.24 (95% CI 0.21, 0.28) of HC recipients (N = 119), p = 0.481, data not shown), and a higher proportion of HBPC recipients died (0.21 (95% CI 0.16, 0.26), N = 51) compared to HC recipients (0.09 (95% CI 0.06, 0.12), N = 43, p = <.0001, data not shown). Among those who died, a higher proportion of HBPC recipients (0.45 (95% CI 0.31, 0.60), N = 23) versus HC recipients (0.37 (95% CI 0.23, 0.53), N = 16) died outside of hospital, although this result was non-significant (p = 0.439, data not shown).

This study used a retrospective before-after analysis of administrative data to assess the influence of two different services started in two different cohorts over the same time period. Both groups were community-dwelling seniors and both had experienced a change in health status over the same time period, prompting referral to either HBPC or HC. Both groups had a similar distribution of some case mix characteristics (sex, RAI-HC CHESS and MAPLe, and living situation) at the time of service start. Despite these similarities, those starting HBPC had a significantly higher rate of hospital services use compared to the HC group at baseline. The HBPC group was already receiving HC and was also therefore functionally frailer than the HC group at baseline. Based on the association of frailty and hospital use [30‐32], the lower rates of hospital use seen at baseline by the HC versus HBPC group are, therefore, not surprising.

In the HBPC group, after start of HBPC, there was a non-significant decrease in ED visits and no change in hospital admission rates. How should the observed “no change” in hospital use between the time periods for the HBPC group be interpreted? If the expected trajectory of frail older adults’ hospital use is that of increased use over time, then the observed stabilization of rates seen in HBPC recipients after receipt of the service may be interpreted as a positive outcome. This interpretation is not unreasonable given the evidence for declining function and higher hospital use [30, 33]. The significantly greater proportion of HBPC recipients that died post service start compared to the HC group, and the known association of higher hospital use in the last 6 months of life [34], is another reason one might expect those receiving HBPC to have increasing rates of hospital use. However, despite considerable frailty and greater mortality of this group, hospital use rates remained unchanged.

For the HC group, in the period after starting HC services, there was a significant increase in hospital use for both outcomes such that the crude ED visit rate in the “after” period surpassed that of the HBPC group, and HC hospital admissions rates began to approximate those of the HBPC group. What factors might explain this? Firstly, these individuals were frail enough to begin to qualify for HC suggesting a major decline in health status. On this basis alone, the HC group would be expected to have increased hospital use over time. HC combined with usual primary care would be unlikely to bend this predictable rise given that HC services are only available during business hours, and usual primary care has variable provision of 24/7 crisis care with less than half of surveyed family physicians in Canada reporting an after-hours arrangement for their patients in 2015 [35]. Moreover, even when a health crisis occurs during daytime and business hours, neither HC nor usual primary care providers have the capacity to drop everything to attend to health crises in the home. In the absence of responsive care, the default action would therefore be to call the ambulance and go to hospital. Furthermore, communication between the “silos” of HC and primary medical care has been described as time-consuming and challenging [24], and only a minority of surveyed Canadian family physicians reported routine communication with HC and/or regular notification by HC about a change in their patients’ condition [35]. A future trial that randomizes receipt of HC versus HBPC to a previously HC naïve group of community-dwelling older adults, whose use is expected to rise over time, might provide valuable insights into the effect of HBPC on hospital use.

While limited, there has been some prior published US research on HBPC. Two randomized controlled trials found lower hospital costs ($17,805 USD versus $22,096 USD) [17] and lower ED visits and hospital admissions [13]. In both US studies, the study populations were younger and deliberately selected for socio-economic vulnerability, unlike the Vancouver HBPC group where there is no user fee for access and the services are covered by a single-payer public system. A third randomized controlled trial whose population was more similar to our HBPC population, found that team-managed HBPC for frail elderly US veterans resulted in a 22% relative decrease in hospital readmissions for a subset of individuals with severe disability only, and the effect was not sustained at 12 months [14]. A Quebec study demonstrated decreased functional decline and a smaller proportion of participants wishing to be institutionalized, but no influence on hospital use, among participants of an integrated home and primary care service delivery model, compared to controls [36]. One other Canadian before-after study showed a significant reduction in hospital use [15] with HBPC. However, the calculated rates in this study were not done with any offset of person-days of observation in the denominator making comparison difficult.

The research on HC and hospital use has also been mixed. Two US studies on HC intervention delivered by an advance practice nurse, and targeted at older adults recently admitted to hospital with congestive heart failure [37] and COPD [38] respectively, both found fewer readmissions in the intervention group. A Canadian randomized controlled trial of preventive home visits by a nurse to frail elderly clients also found no effects on mortality, institutional placement, or the combined use of health services utilization [39]. More recently a large Canadian report on the cost-effectiveness of HC found that hospital costs accounted for 30 to 60% of the overall costs for HC clients [40]. A major challenge of research evaluating both HC and HBPC models is the considerable heterogeneity in the services associated with each of these and the target populations for whom such services are delivered. Moreover, since there is a community expectation of the right to HC services for those who qualify in every province, randomization of access to usual HC would be unethical. However, a future “real world” trial with randomization to HBPC versus HC services for those starting to qualify for HC, may help to understand whether HBPC is able to influence hospital use at an earlier stage in the frailty trajectory. A challenge with such a trial would be the requirement that individuals leave their usual family physician, with whom many have had a longstanding relationship, when they are not yet homebound.

It is also possible that the HBPC cohort were comprised of individuals who disproportionately chose to remain at home when acutely ill, foregoing potential access to life-extending services and opting instead for a home death. This is supported by the greater Canadian Triage and Acuity Scale (CTAS) levels (1, 2 and 3) at time of presentation to the ED seen in the HBPC compared to the HC group, both before and after the start of the HBPC service.

The presence of 24/7 responsive HBPC clinicians who provide pro-active advance care planning and symptom management for palliation at the time of a health crisis may further contribute to a greater proportion of families and patients opting for comfort care versus life extension. Forty-five percent of the HBPC compared to 3% of the HC group died outside the hospital. Although this difference was not statistically significant, possibly due to the small sample size for this outcome, it supports the hypothesis that more HBPC recipients may be opting for death at home over hospital and life prolongation. Research to explore the advance care planning decision-making of frail homebound recipients of HBPC for a “do not hospitalize” directive compared to other frail populations would be another important line of future research.

The study crude ED visit rates for both the HBPC and HC groups are higher than those reported for Vancouver nursing home care and assisted living residents (1.8 per 1000 PD and 3.4 per 1000 PD, respectively) [41] and for Ontario nursing home residents (2.1 per 1000 PD) [42]. This likely reflects the advanced frailty of homebound seniors who continue to live in the community with relatively lower levels of support compared to those in assisted living and nursing home settings. Indeed prior research from British Columbia has demonstrated a stabilizing effect of assisted living with 18,000 more hospital days in the year before compared to the year after moving to assisted living [43].

The association of male sex with higher rates of ED visits [44] and hospital admissions [45, 46] has been described in previous studies. Likewise the strong association of death as an independent predictor of hospital use has been widely described in health services research [47, 48]. Higher age was inversely associated with hospital use and both groups demonstrated a gradient effect of progressively lower adjusted incidence rate ratios for ED visits and hospital admissions with each advancing age group compared to those less than 80 years. Prior research from Ontario has also found significantly decreased hospital use by nursing home residents 90 years and over compared to individuals between 70 and 79 years in the last six months of life [49].

This study had a number of limitations. Firstly, like all before-after studies, the findings are subject to possible regression to the mean and the influence of secular effects. While we tried to partially address this by choosing to examine two community-dwelling senior populations, each starting new (but different) home-based services over the same time period, the populations were sufficiently different to make them non-comparable as true controls thus limiting the generalizability of conclusions. Second, like all retrospective observational studies there is risk of unmeasured bias and confounding. Despite these limitations, the study adds to a relatively small amount of research on HBPC, HC and hospital use [50, 51]. Further research is needed given both the expected higher use of acute health services with advancing age and the need to find models that support the desire of many older adults to remain in their homes as long as possible.

This retrospective cohort study explored the effect of two different programs in two frail populations over the same time period in relation to their impact on hospital use. After enrollment in integrated HBPC, ED visit rates and hospital admission rates stabilized. After starting HC with usual primary care, ED visit and hospital admission rates for these recipients continued to rise. Although both populations were substantially different, results suggest that expansion of HBPC to individuals at an earlier stage of their frailty trajectory may be an opportunity to “bend the curve” of increasing hospital use seen in the HC cohort, thereby improving care and reducing cost.