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Erschienen in: Clinical and Experimental Nephrology 3/2011

01.06.2011 | Case Report

A case of slowly progressive scleroderma kidney

verfasst von: Masahiro Okabe, Nobuo Tsuboi, Takahide Suzuki, Takashi Yokoo, Yoichi Miyazaki, Yasunori Utsunomiya, Iwao Ohno, Tatsuo Hosoya

Erschienen in: Clinical and Experimental Nephrology | Ausgabe 3/2011

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Abstract

A rapidly progressive renal deterioration accompanied by acute-onset/uncontrolled hypertension characterizes scleroderma renal crisis (SRC), a life-threatening complication that occurs in patients with systemic sclerosis (SSc). To date, however, SSc with advanced renal failure has only rarely been reported in the absence of SRC. We report here an atypical case of diffuse cutaneous SSc where renal insufficiency progressed slowly to end-stage renal failure over a 14-year follow-up period after the diagnosis of SSc. In the renal biopsy, which was obtained at a relatively early stage of renal impairment, we found histological findings consistent with those of scleroderma kidneys. Unlike typical SRC, however, the larger renal arteries seemed to be unaffected. These histological findings were probably responsible for the “slowly progressive” renal impairment over the years without causing typical SRC.
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Metadaten
Titel
A case of slowly progressive scleroderma kidney
verfasst von
Masahiro Okabe
Nobuo Tsuboi
Takahide Suzuki
Takashi Yokoo
Yoichi Miyazaki
Yasunori Utsunomiya
Iwao Ohno
Tatsuo Hosoya
Publikationsdatum
01.06.2011
Verlag
Springer Japan
Erschienen in
Clinical and Experimental Nephrology / Ausgabe 3/2011
Print ISSN: 1342-1751
Elektronische ISSN: 1437-7799
DOI
https://doi.org/10.1007/s10157-011-0419-z

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