nach oben

Pediatric Nephrology

Erschienen in:

08.02.2017 | Clinical Quiz

A child presenting with severe hypertension and circulatory failure—a diagnostic conundrum: Answers

verfasst von: Werner Keenswijk, Patrick Verloo, Johan Vande Walle

Erschienen in: Pediatric Nephrology | Ausgabe 11/2017

Einloggen, um Zugang zu erhalten

Excerpt

The differential diagnostic options we considered:

Thrombotic microangiopathy (TMA) [atypical hemolytic uremic syndrome (HUS), cobalamin deficiency-associated HUS, non-Shiga toxin-infectious HUS, ADAMTS13 deficiency]
Systemic lupus erythematosus
Polyarteritis nodosa
Neuroblastoma/pheochromocytoma
Tumor lysis syndrome secondary to leukemia
Sepsis with acute kidney injury (AKI)
Acute disseminated encephalomyelitis
Hyperthyroidism (adenoma, auto immune)
Other causes of glomerulonephritis, e.g. C3 glomerulonephritis/post-infectious glomerulonephritis.

…

Flynn JT, Tullus K (2009) Severe hypertension in children and adolescents: pathophysiology and treatment. Pediatr Nephrol 24:1101–1112CrossRefPubMed

Suresh S, Mahajan P, Kamat D (2005) Emergency management of pediatric hypertension. Clin Pediatr 44:739–745CrossRef

Bradley A, Maron BA, Loscalzo J (2009) The treatment of hyperhomocysteinemia. Annu Rev Med 60:39–54CrossRef

Kind T, Levy J, Lee M, Kaicker S, Nicholson JF, Kane SA (2002) Cobalamin C disease presenting as hemolytic-uremic syndrome in the neonatal period. J Pediatr Hematol Oncol 24:327–329CrossRefPubMed

Guigonis V, Frémeaux-Bacchi V, Giraudier S, Favier R, Borderie D, Massy Z, Mougenot B, Rosenblatt DS, Deschênes G (2005) Late-onset thrombocytic microangiopathy caused by cblC disease: association with a factor H mutation. Am J Kidney Dis 45:588–595CrossRefPubMed

Chenel C, Wood C, Gourrier E, Zittoun J, Casadevall I, Ogier H (1993) Neonatal hemolytic-uremic syndrome, methylmalonic aciduria and homocystinuria caused by intracellular vitamin B 12 deficiency. Value of etiological diagnosis. Arch Fr Pediatr 50:749–754PubMed

Sharma AP, Greenberg CR, Prasad AN, Prasad C (2007) Hemolytic uremic syndrome (HUS) secondary to cobalamin C (Cbl C) disorder. Pediatr Nephrol 22:2097–2103CrossRefPubMed

Cornec-Le Gall E, Delmas Y, De Parscau L, Doucet L, Ogier H, Benoist JF, Fremeaux-Bacchi V, Le Meur Y (2014) Adult-onset eculizumab resistant hemolytic uremic syndrome associated with cobalamin C deficiency. Am J Kidney Dis 63:119–123CrossRefPubMed

Tsai HM, Lian EC (1998) Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura. N Engl J Med 339:1585–1594CrossRefPubMedPubMedCentral

10.

Carrillo-Carrasco N, Chandler RJ, Venditti CP (2012) Combined methylmalonic acidemia and homocystinuria, cblC type. I. Clinical presentations, diagnosis and management. J Inherit Metab Dis 35:91–102CrossRefPubMed

11.

Nester CM, Andreoli SP (2009) Renal involvement in children with HUS. In: Avner ED, Harmon PN, Niaudet P, Yoshikawa N (eds) Pediatric nephrology, 6th edn, Springer, Berlin Heidelberg, pp 1490–1520

12.

Schick P, Conrad ME (2016) Pernicious anemia. Available online at: www.medscape.com Accessed 16 Dec 2016

13.

Imbard A, Benoist JF, Esse R, Gupta S, Lebon S, de Vriese AS, de Baulny HO, Kruger W, Schiff M, Blom HJ (2015) High homocysteine induces betaine depletion. Biosci Rep 35:e00222CrossRefPubMedPubMedCentral

14.

Menni F, Testa S, Guez S, Chiarelli G, Alberti L, Esposito S (2012) Neonatal atypical hemolytic uremic syndrome due to methylmalonic aciduria and homocystinuria. Pediatr Nephrol 27:1401–1405CrossRefPubMed

15.

Schiff M, Blom HJ (2012) Treatment of inherited homocystinurias. Neuropediatrics 43:295–304CrossRefPubMed

16.

Stokes MB, Zviti R, Lin F, D’Agati VD (2016) An unusual cause of hypertension with hematuria and proteinuria: Answers. Pediatr Nephrol 31:2265–2270CrossRefPubMed

17.

Beck BB, Van Spronsen F, Diepstra A, Berger R, Kömhoff M (2016) Renal thrombotic microangiopathy in patients with cblC defect: review of an under-recognized entity. Pediatr Nephrol. doi:10.1007/s00467-016-3399-0 PubMedPubMedCentral

18.

Nardi PM, Haller JO, Friedman AP, Slovis TL, Scaffer RM (1985) Renal manifestation of Kawasaki’s disease. Pediatr Radiol 15:116–118CrossRefPubMed

19.

Riccabona M (2006) Renal failure in neonates, infants, and children: the role of ultrasound. Ultrasound Clin 1:457–469CrossRef

20.

Keenswijk W, Vande Walle J (2016) An atypical case of a 2-year-old boy with acute kidney injury: a race against time. Answers. Pediatr Nephrol. doi:10.1007/s00467-016-3516-0

21.

Ellis D, Miyashita Y (2009) Management of the hypertensive child. In: Avner ED, Harmon PN, Niaudet P, Yoshikawa N (ed) Pediatric nephrology, 6th edn, Springer, Berlin Heidelberg, pp 2023–2097

Titel: A child presenting with severe hypertension and circulatory failure—a diagnostic conundrum: Answers
verfasst von: Werner Keenswijk
Patrick Verloo
Johan Vande Walle
Publikationsdatum: 08.02.2017
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Nephrology / Ausgabe 11/2017
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-017-3600-0

Neu im Fachgebiet Pädiatrie

18.04.2024 | Spinale Muskelatrophien | Nachrichten

Update Pädiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

A child presenting with severe hypertension and circulatory failure—a diagnostic conundrum: Answers

Excerpt

Neu im Fachgebiet Pädiatrie

Spinale Muskelatrophie: Neugeborenen-Screening lohnt sich

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

Zunahme von Geschlechtsinkongruenz und -dysphorie registriert

Stillende Frauen haben geringeres kardiovaskuläres Risiko

Update Pädiatrie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 11/2017

Is CD44 in glomerular parietal epithelial cells a pathological marker of renal function deterioration in primary focal segmental glomerulosclerosis?

Refractory skin lesion, hypertension, and acute kidney injury in a young boy: Answers

The gut–kidney axis

The effect of vitamin D and calcium supplementation in pediatric steroid-sensitive nephrotic syndrome

Erratum to: Evaluation of the safety and efficacy of metoprolol infusion for children and adolescents with hypertensive crises: a retrospective case series

Health-related quality of life of children with pre-dialysis chronic kidney disease

Neu im Fachgebiet Pädiatrie

Spinale Muskelatrophie: Neugeborenen-Screening lohnt sich

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

Zunahme von Geschlechtsinkongruenz und -dysphorie registriert

Stillende Frauen haben geringeres kardiovaskuläres Risiko

Update Pädiatrie