A Comparative Evaluation of Platelet-Rich Fibrin and Platelet-Rich Fibrin Matrix in Terms of pH, Antimicrobial Potential and Histological Presentation: An In vitro Study
- 04.06.2025
- COMPARATIVE STUDY
Erschienen in:
- Verfasst von
- Jasmine
- Hemant Batra
- Vandana Chhabra
- Anubha Gulati
- Sonia B. Bhardwaj
- Erschienen in
- Journal of Maxillofacial and Oral Surgery | Ausgabe 4/2025
Abstract
Background
In recent times, autologous platelet concentrates (APCs) like platelet-rich fibrin (PRF) and platelet-rich fibrin matrix (PRFM) are utilized broadly to promote soft and hard tissue regeneration. The aim of the study was to evaluate PRF and PRFM in terms of pH changes (over a five-day period), antimicrobial potential and histological presentation using light microscopy and field-emission scanning electron microscopic analysis (FESEM).
Materials and Methods
A prospective comparative in vitro study was conducted in which PRF and PRFM samples were prepared from 21 healthy volunteers and a comparative evaluation for the parameters was carried out.
Results
A statistically significant difference was found between PRF and PRFM in terms of pH over a five-day period; antimicrobial efficacy at 48 h; average thickness of fibrin; distribution of platelets and leucocytes entrapped in fibrin matrix.
Conclusion
From our research study, it can be concluded that PRF when compared to PRFM showed abundant entrapment of platelets and leucocytes enmeshed in the 3-D fibrin matrix which is responsible for its better antimicrobial property. PRF also showed increasing acidity over days which accelerates the process of wound healing at the injury site. Thus, PRF is a better autologous platelet concentrate than PRFM.
Anzeige
- Titel
- A Comparative Evaluation of Platelet-Rich Fibrin and Platelet-Rich Fibrin Matrix in Terms of pH, Antimicrobial Potential and Histological Presentation: An In vitro Study
- Verfasst von
-
Jasmine
Hemant Batra
Vandana Chhabra
Anubha Gulati
Sonia B. Bhardwaj
- Publikationsdatum
- 04.06.2025
- Verlag
- Springer India
- Erschienen in
-
Journal of Maxillofacial and Oral Surgery / Ausgabe 4/2025
Print ISSN: 0972-8279
Elektronische ISSN: 0974-942X - DOI
- https://doi.org/10.1007/s12663-025-02619-9
Dieser Inhalt ist nur sichtbar, wenn du eingeloggt bist und die entsprechende Berechtigung hast.
