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Erschienen in: The International Journal of Cardiovascular Imaging 3/2017

22.11.2016 | Original Paper

A comparison study between 3D T2-weighted SPACE and conventional 2D T2-weighted turbo spin echo in assessment of carotid plaque

verfasst von: Peng Lv, Yuanyuan Dai, Jiang Lin, Weisheng Zhang, Hao Liu, Hui Liu, Xiao Tang

Erschienen in: The International Journal of Cardiovascular Imaging | Ausgabe 3/2017

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Abstract

The aim of this study was to compare 3D T2-weighted sampling perfection with application optimized contrast using different flip angle evolutions (T2w SPACE) with conventional 2D T2w turbo-spin echo (TSE) in plaque imaging of carotid artery. 45 patients underwent 3.0-T MRI for carotid arteries imaging. MR sequences included T2w SPACE, T2w TSE, Time of flight (TOF) and T1-weighted (T1w) TSE. The signal intensity of intra-plaque hemorrhage (IPH), lipid-rich necrotic core (LRNC), and loose matrix (LM) were measured and their contrast ratios (CRs) against adjacent muscle were calculated. CRs from T2w SPACE and T2w TSE were compared to each other. CRs of LM, LRNC, and IPH measured on T2w SPACE were 1.74–3.04 (2.44), 0.98–1.66 (1.39), and 1.91–2.93 (2.51), respectively. CRs of LM, LRNC, and IPH on T2w TSE were 1.97–3.41 (2.44), 1.18–1.73 (1.43), and 2.26–3.75 (2.26), respectively. There was no significant difference of CR of the carotid plaques between T2w SPACE and T2w TSE (p = 0.455). Markedly significant differences of CRs were found between LM and LRNC (p < 0.001), and between LRNC and IPH (p < 0.001) on T2w SPACE and T2w TSE. T2w SPACE was comparable with conventional T2w TSE in characterization of carotid plaque.
Literatur
1.
Zurück zum Zitat Barnett HJ, Gunton RW, Eliasziw M et al (2001) Causes and severity of ischemic stroke in patients with internal carotid artery stenosis. JAMA 283:1429–1436CrossRef Barnett HJ, Gunton RW, Eliasziw M et al (2001) Causes and severity of ischemic stroke in patients with internal carotid artery stenosis. JAMA 283:1429–1436CrossRef
2.
Zurück zum Zitat Rothwell PM, Eliasziw M, Gutnikov SA et al (2003) Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. The Lancet 361:107–116CrossRef Rothwell PM, Eliasziw M, Gutnikov SA et al (2003) Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. The Lancet 361:107–116CrossRef
3.
Zurück zum Zitat Rothwell PM, Coull AJ, Silver LE et al (2005) Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study). The Lancet 366:1773–1783CrossRef Rothwell PM, Coull AJ, Silver LE et al (2005) Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study). The Lancet 366:1773–1783CrossRef
4.
Zurück zum Zitat van den Bouwhuijsen QJ, Vernooij MW, Hofman A, Krestin GP, van der Lugt A, Witteman JC (2012) Determinants of magnetic resonance imaging detected carotid plaque components: the Rotterdam Study. Eur Heart J 33:221–229CrossRefPubMed van den Bouwhuijsen QJ, Vernooij MW, Hofman A, Krestin GP, van der Lugt A, Witteman JC (2012) Determinants of magnetic resonance imaging detected carotid plaque components: the Rotterdam Study. Eur Heart J 33:221–229CrossRefPubMed
5.
Zurück zum Zitat de Weert TT, Cretier S, Groen HC et al (2009) Atherosclerotic plaque surface morphology in the carotid bifurcation assessed with multidetector computed tomography angiography. Stroke 40:1334–1340CrossRefPubMed de Weert TT, Cretier S, Groen HC et al (2009) Atherosclerotic plaque surface morphology in the carotid bifurcation assessed with multidetector computed tomography angiography. Stroke 40:1334–1340CrossRefPubMed
6.
Zurück zum Zitat Saam T, Cai J, Ma L et al (2006) Comparison of symptomatic and asymptomatic atherosclerotic carotid plaque features with in vivo MR imaging. Radiology 240:464–472CrossRefPubMedPubMedCentral Saam T, Cai J, Ma L et al (2006) Comparison of symptomatic and asymptomatic atherosclerotic carotid plaque features with in vivo MR imaging. Radiology 240:464–472CrossRefPubMedPubMedCentral
7.
Zurück zum Zitat Zhao H, Zhao X, Liu X et al (2013) Association of carotid atherosclerotic plaque features with acute ischemic stroke: a magnetic resonance imaging study. Eur J Radiol 82:e465–e470CrossRefPubMedPubMedCentral Zhao H, Zhao X, Liu X et al (2013) Association of carotid atherosclerotic plaque features with acute ischemic stroke: a magnetic resonance imaging study. Eur J Radiol 82:e465–e470CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Tartari S, Rizzati R, Righi R et al (2011) High-resolution MRI of carotid plaque with a neurovascular coil and contrast-enhanced MR angiography: one-stop shopping for the comprehensive assessment of carotid atherosclerosis. AJR Am J Roentgenol 196:1164–1171CrossRefPubMed Tartari S, Rizzati R, Righi R et al (2011) High-resolution MRI of carotid plaque with a neurovascular coil and contrast-enhanced MR angiography: one-stop shopping for the comprehensive assessment of carotid atherosclerosis. AJR Am J Roentgenol 196:1164–1171CrossRefPubMed
9.
Zurück zum Zitat Remonda L, Senn P, Barth A, Arnold M, Lovblad KO, Schroth G (2002) Contrast-enhanced 3D MR angiography of the carotid artery: comparison with conventional digital subtraction angiography. AJNR Am J Neuroradiol 23:213–219PubMed Remonda L, Senn P, Barth A, Arnold M, Lovblad KO, Schroth G (2002) Contrast-enhanced 3D MR angiography of the carotid artery: comparison with conventional digital subtraction angiography. AJNR Am J Neuroradiol 23:213–219PubMed
10.
Zurück zum Zitat Kwee RM, van Engelshoven JMA, Mess WH et al (2009) Reproducibility of fibrous cap status assessment of carotid artery plaques by contrast-enhanced MRI. Stroke 40:3017–3021CrossRefPubMed Kwee RM, van Engelshoven JMA, Mess WH et al (2009) Reproducibility of fibrous cap status assessment of carotid artery plaques by contrast-enhanced MRI. Stroke 40:3017–3021CrossRefPubMed
11.
Zurück zum Zitat Fan Z, Zhang Z, Chung Y et al (2010) Carotid arterial wall MRI at 3 T using 3D variable-flip-angle turbo spin-echo (TSE) with flow-sensitive dephasing (FSD). J Magn Reson Imaging 31:645–654CrossRefPubMedPubMedCentral Fan Z, Zhang Z, Chung Y et al (2010) Carotid arterial wall MRI at 3 T using 3D variable-flip-angle turbo spin-echo (TSE) with flow-sensitive dephasing (FSD). J Magn Reson Imaging 31:645–654CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Mihai G, Winner MW, Raman SV, Rajagopalan S, Simonetti OP, Chung Y (2012) Assessment of carotid stenosis using three-dimensional T2-weighted dark blood imaging: initial experience. J Magn Reson Imaging 35:449–455CrossRefPubMed Mihai G, Winner MW, Raman SV, Rajagopalan S, Simonetti OP, Chung Y (2012) Assessment of carotid stenosis using three-dimensional T2-weighted dark blood imaging: initial experience. J Magn Reson Imaging 35:449–455CrossRefPubMed
13.
Zurück zum Zitat Mugler JP, Bao SM, Mulkern RV et al (2000) Optimized single-slab three-dimensional spin-echo MR imaging of the brain. Radiology 216:891–899CrossRefPubMed Mugler JP, Bao SM, Mulkern RV et al (2000) Optimized single-slab three-dimensional spin-echo MR imaging of the brain. Radiology 216:891–899CrossRefPubMed
14.
Zurück zum Zitat Lichy MP, Wietek BM, Mugler JP et al (2005) Magnetic resonance imaging of the body trunk using a single-slab, 3-dimensional, T2-weighted turbo-spin-echo sequence with high sampling efficiency (SPACE) for high spatial resolution imaging. Invest Radiol 40:754–760CrossRefPubMed Lichy MP, Wietek BM, Mugler JP et al (2005) Magnetic resonance imaging of the body trunk using a single-slab, 3-dimensional, T2-weighted turbo-spin-echo sequence with high sampling efficiency (SPACE) for high spatial resolution imaging. Invest Radiol 40:754–760CrossRefPubMed
15.
Zurück zum Zitat Lv P, Lin J, Guo D et al (2014) Detection of carotid artery stenosis: a comparison between 2 unenhanced MRAs and dual-source CTA. AJNR Am J Neuroradiol 35:2360–2365CrossRefPubMed Lv P, Lin J, Guo D et al (2014) Detection of carotid artery stenosis: a comparison between 2 unenhanced MRAs and dual-source CTA. AJNR Am J Neuroradiol 35:2360–2365CrossRefPubMed
16.
Zurück zum Zitat Njemanze PC, Beck OJ, Gomez CR, Horenstein S, Cujec B, Polasek P, Voll C et al (1991) North American Symptomatic Carotid Endarterectomy Trial: methods, patient characteristics and progress. Stroke 22:711–720CrossRef Njemanze PC, Beck OJ, Gomez CR, Horenstein S, Cujec B, Polasek P, Voll C et al (1991) North American Symptomatic Carotid Endarterectomy Trial: methods, patient characteristics and progress. Stroke 22:711–720CrossRef
17.
Zurück zum Zitat Yuan C, Mitsumori LM, Ferguson MS et al (2001) In vivo accuracy of multispectral magnetic resonance imaging for identifying lipid-rich necrotic cores and intraplaque hemorrhage in advanced human carotid plaques. Circulation 104:2051–2056CrossRefPubMed Yuan C, Mitsumori LM, Ferguson MS et al (2001) In vivo accuracy of multispectral magnetic resonance imaging for identifying lipid-rich necrotic cores and intraplaque hemorrhage in advanced human carotid plaques. Circulation 104:2051–2056CrossRefPubMed
18.
Zurück zum Zitat Cai JM (2002) Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging. Circulation 106:1368–1373CrossRefPubMed Cai JM (2002) Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging. Circulation 106:1368–1373CrossRefPubMed
19.
Zurück zum Zitat Saam T, Ferguson MS, Yarnykh VL et al (2004) Quantitative evaluation of carotid plaque composition by in vivo MRI. Arterioscler Thromb Vasc Biol 25:234–239PubMed Saam T, Ferguson MS, Yarnykh VL et al (2004) Quantitative evaluation of carotid plaque composition by in vivo MRI. Arterioscler Thromb Vasc Biol 25:234–239PubMed
20.
Zurück zum Zitat Cappendijk VC, Cleutjens KB, Kessels AG et al (2005) Assessment of human atherosclerotic carotid plaque components with multisequence MR imaging: initial experience. Radiology 234:487–492CrossRefPubMed Cappendijk VC, Cleutjens KB, Kessels AG et al (2005) Assessment of human atherosclerotic carotid plaque components with multisequence MR imaging: initial experience. Radiology 234:487–492CrossRefPubMed
21.
Zurück zum Zitat Cai J (2005) In vivo quantitative measurement of intact fibrous cap and lipid-rich necrotic core size in atherosclerotic carotid plaque: comparison of high-resolution, contrast-enhanced magnetic resonance imaging and histology. Circulation 112:3437–3444CrossRefPubMed Cai J (2005) In vivo quantitative measurement of intact fibrous cap and lipid-rich necrotic core size in atherosclerotic carotid plaque: comparison of high-resolution, contrast-enhanced magnetic resonance imaging and histology. Circulation 112:3437–3444CrossRefPubMed
22.
Zurück zum Zitat Haystead CM, Dale BM, Merkle EM (2008) N/2 ghosting artifacts: elimination at 3.0-T MR cholangiography with SPACE pulse sequence. Radiology 246:589–595CrossRefPubMed Haystead CM, Dale BM, Merkle EM (2008) N/2 ghosting artifacts: elimination at 3.0-T MR cholangiography with SPACE pulse sequence. Radiology 246:589–595CrossRefPubMed
23.
Zurück zum Zitat Chu B (2004) Hemorrhage in the atherosclerotic carotid plaque: a high-resolution MRI study. Stroke 35:1079–1084CrossRefPubMed Chu B (2004) Hemorrhage in the atherosclerotic carotid plaque: a high-resolution MRI study. Stroke 35:1079–1084CrossRefPubMed
24.
Zurück zum Zitat Touze E, Toussaint JF, Coste J et al (2007) Reproducibility of high-resolution MRI for the identification and the quantification of carotid atherosclerotic plaque components: consequences for prognosis studies and therapeutic trials. Stroke 38:1812–1819CrossRefPubMed Touze E, Toussaint JF, Coste J et al (2007) Reproducibility of high-resolution MRI for the identification and the quantification of carotid atherosclerotic plaque components: consequences for prognosis studies and therapeutic trials. Stroke 38:1812–1819CrossRefPubMed
Metadaten
Titel
A comparison study between 3D T2-weighted SPACE and conventional 2D T2-weighted turbo spin echo in assessment of carotid plaque
verfasst von
Peng Lv
Yuanyuan Dai
Jiang Lin
Weisheng Zhang
Hao Liu
Hui Liu
Xiao Tang
Publikationsdatum
22.11.2016
Verlag
Springer Netherlands
Erschienen in
The International Journal of Cardiovascular Imaging / Ausgabe 3/2017
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-016-1017-7

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