Skip to main content
Erschienen in: Obesity Surgery 8/2020

07.05.2020 | Original Contributions

A French National Study on Gastropleural and Gastrobronchial Fistulas After Bariatric Surgery: the Impact of Therapeutic Strategy on Healing

verfasst von: L. Marie, M. Robert, L. Montana, F. De Dominicis, W. Ezzedine, R. Caiazzo, L. Fournel, A. Mancini, R. Kassir, S. Boullu, M. Barthet, X. B. D’Journo, Thierry Bège

Erschienen in: Obesity Surgery | Ausgabe 8/2020

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Gastropleural and gastrobronchial fistulas (GPF/GBFs) are serious but rare complications after bariatric surgery whose management is not consensual. The aim was to establish a cohort and evaluate different clinical presentations and therapeutic options.

Materials and Methods

A multicenter and retrospective study analyzing GPF/GBFs after bariatric surgery in France between 2007 and 2018, via a questionnaire sent to digestive and thoracic surgery departments.

Results

The study included 24 patients from 9 surgical departments after initial bariatric surgery (21 sleeve gastrectomies; 3 gastric bypass) for morbid obesity (mean BMI = 42 ± 8 kg/m2). The GPF/GBFs occurred, on average, 124 days after bariatric surgery, complicating an initial post-operative gastric fistula (POGF) in 66% of cases. Endoscopic digestive treatment was performed in 79% of cases (n = 19) associated in 25% of cases (n = 6) with thoracic endoscopy. Surgical treatment was performed in 83% of cases (n = 20): thoracic surgery (n = 5), digestive surgery (n = 8), and combined surgery (n = 7). No patient died. Overall morbidity was 42%. The overall success rate of the initial and secondary strategies was 58.5% and 90%, respectively. The average healing time was approximately 7 months. Patients who had undergone thoracic surgery (n = 12) had more initial management failures (n = 9/12) than patients who had not (n = 3/12), p = 0.001.

Conclusion

Complex and life-threatening fistulas that are revealed late require a multidisciplinary strategy. Thoracic surgery should be reserved once the abdominal leak heals; otherwise, it is associated with a higher risk of failure.
Literatur
1.
Zurück zum Zitat Lazzati A, Audureau E, Hemery F, et al. Reduction in early mortality outcomes after bariatric surgery in France between 2007 and 2012: a nationwide study of 133,000 obese patients. Surgery. 2016;159(2):467–74.PubMedCrossRef Lazzati A, Audureau E, Hemery F, et al. Reduction in early mortality outcomes after bariatric surgery in France between 2007 and 2012: a nationwide study of 133,000 obese patients. Surgery. 2016;159(2):467–74.PubMedCrossRef
3.
Zurück zum Zitat Vidarsson B, Sundbom M, Edholm D. Incidence and treatment of leak at the gastrojejunostomy in roux-en-Y gastric bypass: a cohort study of 40,844 patients. Surg Obes Relat Dis. 2019;15(7):1075–9.PubMedCrossRef Vidarsson B, Sundbom M, Edholm D. Incidence and treatment of leak at the gastrojejunostomy in roux-en-Y gastric bypass: a cohort study of 40,844 patients. Surg Obes Relat Dis. 2019;15(7):1075–9.PubMedCrossRef
4.
Zurück zum Zitat Gagner M. Decreased incidence of leaks after sleeve gastrectomy and improved treatments. Surg Obes Relat Dis. 2014;10(4):611–2.PubMedCrossRef Gagner M. Decreased incidence of leaks after sleeve gastrectomy and improved treatments. Surg Obes Relat Dis. 2014;10(4):611–2.PubMedCrossRef
5.
Zurück zum Zitat Rosenthal RJ. International Sleeve Gastrectomy Expert Panel, Diaz AA, Arvidsson D, Baker RS, Basso N, et al. International Sleeve Gastrectomy Expert Panel Consensus Statement: best practice guidelines based on experience of >12,000 cases. Surg Obes Relat Dis. 2012;8(1):8–19.PubMedCrossRef Rosenthal RJ. International Sleeve Gastrectomy Expert Panel, Diaz AA, Arvidsson D, Baker RS, Basso N, et al. International Sleeve Gastrectomy Expert Panel Consensus Statement: best practice guidelines based on experience of >12,000 cases. Surg Obes Relat Dis. 2012;8(1):8–19.PubMedCrossRef
6.
Zurück zum Zitat Burgos AM, Braghetto I, Csendes A, et al. Gastric leak after laparoscopic-sleeve gastrectomy for obesity. Obes Surg. 2009;19(12):1672–7.PubMedCrossRef Burgos AM, Braghetto I, Csendes A, et al. Gastric leak after laparoscopic-sleeve gastrectomy for obesity. Obes Surg. 2009;19(12):1672–7.PubMedCrossRef
7.
Zurück zum Zitat Sakran N, Goitein D, Raziel A, et al. Gastric leaks after sleeve gastrectomy: a multicenter experience with 2,834 patients. Surg Endosc. 2013;27(1):240–5.PubMedCrossRef Sakran N, Goitein D, Raziel A, et al. Gastric leaks after sleeve gastrectomy: a multicenter experience with 2,834 patients. Surg Endosc. 2013;27(1):240–5.PubMedCrossRef
8.
Zurück zum Zitat van de Vrande S, Himpens J, El Mourad H, et al. Management of chronic proximal fistulas after sleeve gastrectomy by laparoscopic roux-limb placement. Surg Obes Relat Dis. 2013;9(6):856–61.PubMedCrossRef van de Vrande S, Himpens J, El Mourad H, et al. Management of chronic proximal fistulas after sleeve gastrectomy by laparoscopic roux-limb placement. Surg Obes Relat Dis. 2013;9(6):856–61.PubMedCrossRef
9.
Zurück zum Zitat Silva LB, Moon RC, Teixeira AF, et al. Gastrobronchial fistula in sleeve gastrectomy and roux-en-Y gastric bypass--a systematic review. Obes Surg. 2015;25(10):1959–65.PubMedCrossRef Silva LB, Moon RC, Teixeira AF, et al. Gastrobronchial fistula in sleeve gastrectomy and roux-en-Y gastric bypass--a systematic review. Obes Surg. 2015;25(10):1959–65.PubMedCrossRef
10.
Zurück zum Zitat Garcia-Quintero P, Hernandez-Murcia C, Romero R, et al. Gastropleural fistula after bariatric surgery: a report of two cases. J Robot Surg. 2015;9(2):163–6.PubMedCrossRef Garcia-Quintero P, Hernandez-Murcia C, Romero R, et al. Gastropleural fistula after bariatric surgery: a report of two cases. J Robot Surg. 2015;9(2):163–6.PubMedCrossRef
11.
Zurück zum Zitat Bège T, Emungania O, Vitton V, et al. An endoscopic strategy for management of anastomotic complications from bariatric surgery: a prospective study. Gastrointest Endosc. 2011;73(2):238–44.PubMedCrossRef Bège T, Emungania O, Vitton V, et al. An endoscopic strategy for management of anastomotic complications from bariatric surgery: a prospective study. Gastrointest Endosc. 2011;73(2):238–44.PubMedCrossRef
12.
Zurück zum Zitat Gonzalez JM, Lorenzo D, Guilbaud T, et al. Internal endoscopic drainage as first line or second line treatment in case of postsleeve gastrectomy fistulas. Endosc Int Open. 2018;6(6):E745–50.PubMedPubMedCentralCrossRef Gonzalez JM, Lorenzo D, Guilbaud T, et al. Internal endoscopic drainage as first line or second line treatment in case of postsleeve gastrectomy fistulas. Endosc Int Open. 2018;6(6):E745–50.PubMedPubMedCentralCrossRef
13.
Zurück zum Zitat Ghanem OM, Dayyeh BKA, Kellogg TA. Management of gastropleural fistula after revisional bariatric surgery: a hybrid laparoendoscopic approach. Obes Surg. 2017;27(10):2773–7.PubMedCrossRef Ghanem OM, Dayyeh BKA, Kellogg TA. Management of gastropleural fistula after revisional bariatric surgery: a hybrid laparoendoscopic approach. Obes Surg. 2017;27(10):2773–7.PubMedCrossRef
14.
Zurück zum Zitat Nedelcu AM, Skalli M, Deneve E, et al. Surgical management of chronic fistula after sleeve gastrectomy. Surg Obes Relat Dis. 2013;9(6):879–84.PubMedCrossRef Nedelcu AM, Skalli M, Deneve E, et al. Surgical management of chronic fistula after sleeve gastrectomy. Surg Obes Relat Dis. 2013;9(6):879–84.PubMedCrossRef
15.
Zurück zum Zitat Moeller DD, Carpenter PR. Gastrobronchial fistula: case report and review of the English literature. Am J Gastroenterol. 1985;80(7):538–41.PubMed Moeller DD, Carpenter PR. Gastrobronchial fistula: case report and review of the English literature. Am J Gastroenterol. 1985;80(7):538–41.PubMed
16.
Zurück zum Zitat Takeda S-I, Funaki S, Yumiba T, et al. Gastropleural fistula due to gastric perforation after lobectomy for lung cancer. Interact Cardiovasc Thorac Surg. 2005;4(5):420–2.PubMedCrossRef Takeda S-I, Funaki S, Yumiba T, et al. Gastropleural fistula due to gastric perforation after lobectomy for lung cancer. Interact Cardiovasc Thorac Surg. 2005;4(5):420–2.PubMedCrossRef
17.
Zurück zum Zitat Muzaffar MS, Umair B, Asghar A, et al. Gastropleural fistula: an unusual sequel of blunt chest trauma. J Coll Physicians Surg Pak. 2009;19(7):447–9.PubMed Muzaffar MS, Umair B, Asghar A, et al. Gastropleural fistula: an unusual sequel of blunt chest trauma. J Coll Physicians Surg Pak. 2009;19(7):447–9.PubMed
18.
Zurück zum Zitat Guillaud A, Moszkowicz D, Nedelcu M, et al. Gastrobronchial fistula: a serious complication of sleeve gastrectomy. Results of a French Multicentric Study. Obes Surg. 2015;25(12):2352–9.PubMedCrossRef Guillaud A, Moszkowicz D, Nedelcu M, et al. Gastrobronchial fistula: a serious complication of sleeve gastrectomy. Results of a French Multicentric Study. Obes Surg. 2015;25(12):2352–9.PubMedCrossRef
19.
Zurück zum Zitat Lorenzo D, Guilbaud T, Gonzalez JM, et al. Endoscopic treatment of fistulas after sleeve gastrectomy: a comparison of internal drainage versus closure. Gastrointest Endosc. 2018;87(2):429–37.PubMedCrossRef Lorenzo D, Guilbaud T, Gonzalez JM, et al. Endoscopic treatment of fistulas after sleeve gastrectomy: a comparison of internal drainage versus closure. Gastrointest Endosc. 2018;87(2):429–37.PubMedCrossRef
20.
Zurück zum Zitat Seidelman RA, Seidelman J. Closure of gastro-pleuro-bronchial fistula with polymethyl methacrolate and endoclips: a rare complication of gastric bypass surgery. J Bronchology Interv Pulmonol. 2010;17(1):87–9.PubMedCrossRef Seidelman RA, Seidelman J. Closure of gastro-pleuro-bronchial fistula with polymethyl methacrolate and endoclips: a rare complication of gastric bypass surgery. J Bronchology Interv Pulmonol. 2010;17(1):87–9.PubMedCrossRef
21.
Zurück zum Zitat Garrett KA, Rosati C. Gastro-broncho-pleural fistula after laparoscopic gastric band placement. Obes Surg. 2009;19(7):941–3.PubMedCrossRef Garrett KA, Rosati C. Gastro-broncho-pleural fistula after laparoscopic gastric band placement. Obes Surg. 2009;19(7):941–3.PubMedCrossRef
22.
Zurück zum Zitat Albanopoulos K, Tsamis D, Leandros E. Gastrobronchial fistula as a late complication of sleeve gastrectomy. Surg Obes Relat Dis. 2013;9(6):e97–9. Albanopoulos K, Tsamis D, Leandros E. Gastrobronchial fistula as a late complication of sleeve gastrectomy. Surg Obes Relat Dis. 2013;9(6):e97–9.
23.
Zurück zum Zitat Tabbara M, Polliand C, Barrat C. Gastrobronchial fistula: a rare complication of sleeve gastrectomy. J Visc Surg. 2015;152(6):395–6.PubMedCrossRef Tabbara M, Polliand C, Barrat C. Gastrobronchial fistula: a rare complication of sleeve gastrectomy. J Visc Surg. 2015;152(6):395–6.PubMedCrossRef
24.
Zurück zum Zitat Rebibo L, Dhahri A, Berna P, et al. Management of gastrobronchial fistula after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis. 2014;10(3):460–7.PubMedCrossRef Rebibo L, Dhahri A, Berna P, et al. Management of gastrobronchial fistula after laparoscopic sleeve gastrectomy. Surg Obes Relat Dis. 2014;10(3):460–7.PubMedCrossRef
25.
Zurück zum Zitat Bruzzi M, M’Harzi L, Poghosyan T, et al. Anatomical relations between the esogastric junction, the diaphragm, the pleura, and the left lung in chronic esogastro-bronchial and/or esogastropleural fistulas after sleeve gastrectomy. Obes Surg. 2019;29(9):2814–23. Bruzzi M, M’Harzi L, Poghosyan T, et al. Anatomical relations between the esogastric junction, the diaphragm, the pleura, and the left lung in chronic esogastro-bronchial and/or esogastropleural fistulas after sleeve gastrectomy. Obes Surg. 2019;29(9):2814–23.
26.
Zurück zum Zitat Yehoshua RT, Eidelman LA, Stein M, et al. Laparoscopic sleeve gastrectomy--volume and pressure assessment. Obes Surg. 2008;18(9):1083–8.PubMedCrossRef Yehoshua RT, Eidelman LA, Stein M, et al. Laparoscopic sleeve gastrectomy--volume and pressure assessment. Obes Surg. 2008;18(9):1083–8.PubMedCrossRef
27.
Zurück zum Zitat Marie L, Masson C, Gaborit B, et al. An experimental study of intraluminal hyperpressure reproducing a gastric leak following a sleeve gastrectomy. Obes Surg. 2019;29(9):2773–80.PubMedCrossRef Marie L, Masson C, Gaborit B, et al. An experimental study of intraluminal hyperpressure reproducing a gastric leak following a sleeve gastrectomy. Obes Surg. 2019;29(9):2773–80.PubMedCrossRef
28.
Zurück zum Zitat Fuks D, Dumont F, Berna P, et al. Case report-complex management of a postoperative bronchogastric fistula after laparoscopic sleeve gastrectomy. Obes Surg. 2009;19(2):261–4.PubMedCrossRef Fuks D, Dumont F, Berna P, et al. Case report-complex management of a postoperative bronchogastric fistula after laparoscopic sleeve gastrectomy. Obes Surg. 2009;19(2):261–4.PubMedCrossRef
29.
Zurück zum Zitat Aljehani Y, AlQattan AS, Alkuwaiti FA, et al. Thoracic complications of bariatric surgeries: overlooked entities. Obes Surg. 2019;29(8):2485–91. Aljehani Y, AlQattan AS, Alkuwaiti FA, et al. Thoracic complications of bariatric surgeries: overlooked entities. Obes Surg. 2019;29(8):2485–91.
30.
Zurück zum Zitat Alkhatib SG, Levine MS. Gastrobronchial fistula after sleeve gastrectomy: clinical and radiographic findings. Clin Imaging. 2019;53:112–4.PubMedCrossRef Alkhatib SG, Levine MS. Gastrobronchial fistula after sleeve gastrectomy: clinical and radiographic findings. Clin Imaging. 2019;53:112–4.PubMedCrossRef
31.
Zurück zum Zitat Van Gossum A, Pironi L, Chambrier C, et al. Home parenteral nutrition (HPN) in patients with post-bariatric surgery complications. Clin Nutr. 2017;36(5):1345–8.PubMedCrossRef Van Gossum A, Pironi L, Chambrier C, et al. Home parenteral nutrition (HPN) in patients with post-bariatric surgery complications. Clin Nutr. 2017;36(5):1345–8.PubMedCrossRef
32.
Zurück zum Zitat Campos JM, Pereira EF, Evangelista LF, et al. Gastrobronchial fistula after sleeve gastrectomy and gastric bypass: endoscopic management and prevention. Obes Surg. 2011;21(10):1520–9.PubMedCrossRef Campos JM, Pereira EF, Evangelista LF, et al. Gastrobronchial fistula after sleeve gastrectomy and gastric bypass: endoscopic management and prevention. Obes Surg. 2011;21(10):1520–9.PubMedCrossRef
33.
Zurück zum Zitat Iannelli A, Tavana R, Martini F, et al. Laparoscopic roux limb placement over a fistula defect without mucosa-to-mucosa anastomosis: a modified technique for surgical management of chronic proximal fistulas after laparoscopic sleeve gastrectomy. Obes Surg. 2014;24(5):825–8.PubMedCrossRef Iannelli A, Tavana R, Martini F, et al. Laparoscopic roux limb placement over a fistula defect without mucosa-to-mucosa anastomosis: a modified technique for surgical management of chronic proximal fistulas after laparoscopic sleeve gastrectomy. Obes Surg. 2014;24(5):825–8.PubMedCrossRef
34.
Zurück zum Zitat Ramos AC, Ramos MG, Campos JM, et al. Laparoscopic total gastrectomy as an alternative treatment to postsleeve chronic fistula. Surg Obes Relat Dis. 2015;11(3):552–6.PubMedCrossRef Ramos AC, Ramos MG, Campos JM, et al. Laparoscopic total gastrectomy as an alternative treatment to postsleeve chronic fistula. Surg Obes Relat Dis. 2015;11(3):552–6.PubMedCrossRef
35.
Zurück zum Zitat Bruzzi M, Douard R, Voron T, et al. Open total gastrectomy with roux-en-Y reconstruction for a chronic fistula after sleeve gastrectomy. Surg Obes Relat Dis. 2016;12(10):1803–8.PubMedCrossRef Bruzzi M, Douard R, Voron T, et al. Open total gastrectomy with roux-en-Y reconstruction for a chronic fistula after sleeve gastrectomy. Surg Obes Relat Dis. 2016;12(10):1803–8.PubMedCrossRef
36.
Zurück zum Zitat Landreneau JP, Strong AT, Rodriguez JH, et al. Conversion of sleeve gastrectomy to roux-en-Y gastric bypass. Obes Surg. 2018;28(12):3843–50.PubMedCrossRef Landreneau JP, Strong AT, Rodriguez JH, et al. Conversion of sleeve gastrectomy to roux-en-Y gastric bypass. Obes Surg. 2018;28(12):3843–50.PubMedCrossRef
37.
Zurück zum Zitat Al-shurafa H, Alghamdi S, Albenmousa A, et al. Gastropleural fistula after single anastomosis gastric bypass. A case report and review of the literature. Int J Surg Case Rep. 2017;35:82–6.PubMedPubMedCentralCrossRef Al-shurafa H, Alghamdi S, Albenmousa A, et al. Gastropleural fistula after single anastomosis gastric bypass. A case report and review of the literature. Int J Surg Case Rep. 2017;35:82–6.PubMedPubMedCentralCrossRef
Metadaten
Titel
A French National Study on Gastropleural and Gastrobronchial Fistulas After Bariatric Surgery: the Impact of Therapeutic Strategy on Healing
verfasst von
L. Marie
M. Robert
L. Montana
F. De Dominicis
W. Ezzedine
R. Caiazzo
L. Fournel
A. Mancini
R. Kassir
S. Boullu
M. Barthet
X. B. D’Journo
Thierry Bège
Publikationsdatum
07.05.2020
Verlag
Springer US
Erschienen in
Obesity Surgery / Ausgabe 8/2020
Print ISSN: 0960-8923
Elektronische ISSN: 1708-0428
DOI
https://doi.org/10.1007/s11695-020-04655-5

Weitere Artikel der Ausgabe 8/2020

Obesity Surgery 8/2020 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.