A locally infiltrative juxtaglomerular cell tumor with unusual histologic features
- 05.10.2024
- BRIEF REPORT
Erschienen in:
- Verfasst von
- Adriana Hogeboom
- Óscar Toldos
- Huberto García-Muñoz
- Erschienen in
- Virchows Archiv | Ausgabe 6/2025
Abstract
Juxtaglomerular cell tumor (JGCT) is an exceptionally rare renal tumor with a predominantly benign clinical course and classically bland histology. It commonly presents in young adults and manifests as hypertension related to renin secretion. We report a JGCT initially thought to be a renal cell carcinoma. It was unique because of its size, high-grade histologic features and locally infiltrative nature–extension into the renal pelvis. It is unclear whether features such as tumor necrosis, pleomorphism and increased proliferative activity are predictive of metastatic potential and/or locally aggressive behavior. Clinical follow-up may be warranted in such cases.
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- Titel
- A locally infiltrative juxtaglomerular cell tumor with unusual histologic features
- Verfasst von
-
Adriana Hogeboom
Óscar Toldos
Huberto García-Muñoz
- Publikationsdatum
- 05.10.2024
- Verlag
- Springer Berlin Heidelberg
- Erschienen in
-
Virchows Archiv / Ausgabe 6/2025
Print ISSN: 0945-6317
Elektronische ISSN: 1432-2307 - DOI
- https://doi.org/10.1007/s00428-024-03938-x
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