The online version of this article (doi:10.1186/s12885-017-3276-7) contains supplementary material, which is available to authorized users.
Women with breast cancer undergoing chemotherapy suffer from a number of symptoms and report receiving inadequate support from health care professionals. Innovative and easily accessible interventions are lacking. Breast Cancer e-Support is a mobile Application program (App) that provides patients with individually tailored information and a support group of peers and health care professionals. Breast Cancer e-Support aims to promote women’s self-efficacy, social support and symptom management, thus improving their quality of life and psychological well-being.
A single-blinded, multi-centre, randomised, 6-month, parallel-group superiority design will be used. Based on Bandura’s self-efficacy theory and the social exchange theory, Breast Cancer e-Support has four modules: 1) a Learning forum; 2) a Discussion forum; 3) an Ask-the-Expert forum; and 4) a Personal Stories forum. Women with breast cancer (n = 108) who are commencing chemotherapy will be recruited from two university-affiliated hospitals in China. They will be randomly assigned to either control group that receives routine care or intervention group that receives routine care plus access to Breast Cancer e-Support program during their four cycles of chemotherapy. Self-efficacy, social support, symptom distress, quality of life, and anxiety and depression will be measured at baseline, then one week and 12 weeks post-intervention.
This is the first study of its kind in China to evaluate the use of a mobile application intervention with a rigorous research design and theoretical framework. This study will contribute to evidence regarding the effectiveness of a theory-based mobile application to support women with breast cancer undergoing chemotherapy. The results should provide a better understanding of the role of self-efficacy and social support in reducing symptom distress and of the credibility of using a theoretical framework to develop internet-based interventions. The results will provide evidence to support the implementation of an innovative and easily accessible intervention that enhances health outcomes.
ACTRN: ACTRN12616000639426, Registered 17 May, 2016.
Additional file 1: Satisfaction Evaluation Questionnaire. (DOCX 23 kb)12885_2017_3276_MOESM1_ESM.docx
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Cancer incidence and mortality worldwide: IARC CancerBase no.10. GLOBOCAN 2008. International Agency for Research on Cancer: Lyon; 2010.
Health expenditure per capita (current us$). The World Bank. 2017. http://data.worldbank.org/indicator/SH.XPD.PCAP/countries?display=default. Accessed 20 Feb 2017.
Murray E, Burns J, See Tai S, Lai R, Nazareth I. Interactive Health Communication Applications for people with chronic disease. Cochrane Database Syst Rev(4). 2005:CD004274.
van den Berg SW, Gielissen MF, Ottevanger PB, Prins JB. Rationale of the BREAst cancer e-healTH [BREATH] multicentre randomised controlled trial: an internet-based self-management intervention to foster adjustment after curative breast cancer by decreasing distress and increasing empowerment. BMC Cancer. 2012;12:394. CrossRefPubMedPubMedCentral
Wheelock AE, Bock MA, Martin EL, Hwang J, Ernest ML, Rugo HS, et al. SIS.NET: A randomized controlled trial evaluating a web-based system for symptom management after treatment of breast cancer. Cancer. 2015; 121:893–9.
Zhu JM, Ebert L, Chan WC. Integrative review: the effectiveness of internet-based interactive programs for women with breast cancer undergoing treatment. Oncol Nurs Forum. 2017;44:E42–54. PubMed
Wang Y, Li N, Sun Y, Song H, Yang L, Wang Y, et al. The application of mobile phone based symptom management system on breast cancer patients undergoing transitional care with chemotherapy (article in Chinese). Tijian J Nurs. 2015;1:6–8.
Huang X, Hu Y, Lu Z, Huang J, Shen K. Effect of an internet-based support program on depression and disease-related knowledge in breast cancer patients (article in Chinese). J Nurs Sci. 2011;2:1–4.
Internet users (per 100 people). The World Bank. 2017. http://data.worldbank.org/indicator/IT.NET.USER.P2. Accessed 2 Feb 2017.
The Internet users and mobile phone users in China. China Internt Network Information Center. 2017. http://mt.sohu.com/20150726/n417553651.shtml. Accessed 2 Feb 2017 .
Bandura A. Self-efficacy: the exercise of control. New York: Freeman; 1997.
House JS. Work, stress & social support. NY: Addison-Wesley, Reading, MA; 1981.
Telch C: A comparison of Coping Skills Instruction and Support Group Counseling in Alleviating Psychological Distress Among Cancer Patients. (Unpublished doctoral dissertation). Stanford University; 1985.
Zimet GD, Dahlem NW, Zimet SG, Farley GK. The multidimensional scale of perceived social support. J Pers Assess. 1988;52:30–41. CrossRef
Cohen J. Statistical power analysis. Curr Dir Psychol Sci. 1992;1:98–101. CrossRef
Gustafson DH, Hawkins R, McTavish F, Pingree S, Chen WC, Volrathongchai K, et al. Internet-based interactive support for cancer patients: are integrated systems better? Aust J Commun. 2008;58:238–57. CrossRef
Research Randomizer (2016): Research Randomizer. https://www.randomizer.org/. Accessed at May 16, 2016.
IBM Corp. IBM SPSS Statistics Software, Armonk, NY.; 2013.
- A mobile application of breast cancer e-support program versus routine Care in the treatment of Chinese women with breast cancer undergoing chemotherapy: study protocol for a randomized controlled trial
Sally Wai-Chi Chan
- BioMed Central
Neu im Fachgebiet Onkologie
Mail Icon II