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01.01.2018 | Letter to the Editor

A modified direct-heating headspace solid-phase microextraction method for drug screening with urine samples

verfasst von: Hiroshi Fujii, Brian Waters, Kenji Hara, Natsuki Ikematsu, Mio Takayama, Aya Matsusue, Masayuki Kashiwagi, Shin-ichi Kubo

Erschienen in: Forensic Toxicology | Ausgabe 1/2018

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In forensic autopsy cases, it is important to quickly identify the drugs and chemicals that caused poisoning in humans. Previously, we reported a direct-heating headspace solid-phase microextraction (DH-HS-SPME) method for the screening of illicit drugs [1]. The DH-HS-SPME has an advantage in that volatile to non-volatile compounds can be adsorbed to the SPME fiber in the headspace vial that enables comprehensive screening of compounds by gas chromatography–mass spectrometry (GC–MS). In this letter, we present application of this DH-HS-SPME method to actual urine samples from suspects of drug abuse together with some modifications to enhance its sensitivity. …
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Metadaten
Titel
A modified direct-heating headspace solid-phase microextraction method for drug screening with urine samples
verfasst von
Hiroshi Fujii
Brian Waters
Kenji Hara
Natsuki Ikematsu
Mio Takayama
Aya Matsusue
Masayuki Kashiwagi
Shin-ichi Kubo
Publikationsdatum
01.01.2018
Verlag
Springer Japan
Erschienen in
Forensic Toxicology / Ausgabe 1/2018
Print ISSN: 1860-8965
Elektronische ISSN: 1860-8973
DOI
https://doi.org/10.1007/s11419-017-0396-3

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