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23.06.2018 | Case Report

A rare case of atypical pleomorphic adenoma arising from periocular ectopic lacrimal gland

Zeitschrift:
International Ophthalmology
Autoren:
Brynn N. Wajda, Ronald Mancini, Bret Evers, R. Nick Hogan

Abstract

Purpose

To describe features of atypical pleomorphic adenoma, a rare clinical entity, particularly when found in ectopic periocular lacrimal gland tissue.

Methods

Case report of biopsy-confirmed periocular atypical pleomorphic adenoma.

Results

A 35-year-old female presented with a unique orbital lesion found to be ectopic lacrimal gland demonstrating atypical pleomorphic adenoma on formal histopathologic review. Pleomorphic adenoma is pathologically characterized as an epithelial lesion intermixed with mesenchymal elements. It is further classified as atypical with the presence of features such as hypercellularity, regions of necrosis or hyalinization, cellular dysplasia, capsular violation, and malignant characteristics without frank local extension or distant metastases.

Conclusions

Due to its rarity, the natural history and prognosis of atypical pleomorphic adenoma is unclear. Physicians need to recognize this entity, and complete surgical excision with strict follow-up regimens are likely warranted.

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