A rare cause of AA amyloidosis and end-stage kidney failure: Questions

Excerpt

A 14-year-old girl presented with fatigue, diarrhea, and generalized edema lasting for 10 days. She claimed that the diarrhea is watery without any blood or mucous, in the frequency of every 2–3 h and amount of 4 kg/day. She denied any vomiting, fever, cough, and abdominal or joint pain. In her past medical history, frequent upper respiratory tract infections were notable, and she had generalized edema with no proteinuria 3 months ago before her presentation. She was not sexually active and did not smoke cigarettes, drink alcohol, or use illicit drugs. Review of family history revealed that her mother and father were cousins. There was no known family history of kidney disease or inflammatory disease. …