Skip to main content
Erschienen in: Indian Journal of Surgical Oncology 1/2023

11.08.2022 | Original Article

A Retrospective Cohort Study of Gastrosplenic Fistula Secondary to Malignant Etiology: Single-Centre Experience of 5 Cases

verfasst von: Poras Chaudhary, Utsav Bhadana, Subhash Chandran, Achint Agarwal, Neeti Kapur

Erschienen in: Indian Journal of Surgical Oncology | Ausgabe 1/2023

Einloggen, um Zugang zu erhalten

Abstract

Gastrosplenic fistula is an uncommon manifestation of malignancy of the stomach and spleen. The aim of this study is to present our 10-year experience on gastrosplenic fistula secondary to malignant etiology. Endoscopy, imaging, and histopathology records of all the patients with gastric and splenic malignant pathologies were reviewed retrospectively. The protocol was approved by the ethical review board of the institute. Descriptive statistics were used to summarize the data. A total of 5 cases were found to have gastrosplenic fistula. Of these 5 cases, 2 were due to large B cell lymphoma of the spleen, 1 was secondary to Hodgkin’s lymphoma of the stomach, 1 case was due to diffuse large B cell non-Hodgkin’s lymphoma of the stomach, and 1 patient was secondary to gastric adenocarcinoma. Gastrosplenic fistula is an exceptionally rare complication of gastrointestinal malignancy. Lymphoma of the spleen is the commonest cause while gastric adenocarcinoma causing gastrosplenic fistula is extremely rare. Most cases occur spontaneously.
Literatur
1.
Zurück zum Zitat Rothermel LD, Chadwick CL, Thambi-Pillai T (2010) Gastrosplenic fistula: etiologies, diagnostic studies, and surgical management. Int Surg 95:270–272PubMed Rothermel LD, Chadwick CL, Thambi-Pillai T (2010) Gastrosplenic fistula: etiologies, diagnostic studies, and surgical management. Int Surg 95:270–272PubMed
2.
Zurück zum Zitat Garcia MA, Bernardos GL, Vaquero RA, MenchénViso L, Turégano FF (2009) Spontaneous gastrosplenic fistula secondary to primary gastric lymphoma. Rev Esp Enferm Dig 101:76–78 Garcia MA, Bernardos GL, Vaquero RA, MenchénViso L, Turégano FF (2009) Spontaneous gastrosplenic fistula secondary to primary gastric lymphoma. Rev Esp Enferm Dig 101:76–78
4.
Zurück zum Zitat Bird MA, Amjadi D, Behrns KE (2002) Primary splenic lymphoma complicated by hematemesis and gastric erosion. South Med J 95:941–942CrossRefPubMed Bird MA, Amjadi D, Behrns KE (2002) Primary splenic lymphoma complicated by hematemesis and gastric erosion. South Med J 95:941–942CrossRefPubMed
5.
Zurück zum Zitat deScoville A, Bovy P, Demeester P (1967) Radiologic aerosplenomegaly caused by necrotizing splenic lymphosarcoma with double fistulization into the digestive tract. Acta Gastro-Enterol Belg 30:841–847 deScoville A, Bovy P, Demeester P (1967) Radiologic aerosplenomegaly caused by necrotizing splenic lymphosarcoma with double fistulization into the digestive tract. Acta Gastro-Enterol Belg 30:841–847
6.
Zurück zum Zitat Jain V, Pauli E, Sharzehi K, Moyer M (2011) Spontaneous gastrosplenic fistula secondary to diffuse large B-cell lymphoma. Gastrointest Endosc 73:608–609CrossRefPubMed Jain V, Pauli E, Sharzehi K, Moyer M (2011) Spontaneous gastrosplenic fistula secondary to diffuse large B-cell lymphoma. Gastrointest Endosc 73:608–609CrossRefPubMed
7.
Zurück zum Zitat Moran M, Bilgiç I, Dizen H, Dilektaşlı E, Köseoğlu T, Özmen M (2011) Spontaneous gastrosplenic fistula resulting from primary gastric lymphoma: case report and review of the literature. Balkan Med J 28:205–8 Moran M, Bilgiç I, Dizen H, Dilektaşlı E, Köseoğlu T, Özmen M (2011) Spontaneous gastrosplenic fistula resulting from primary gastric lymphoma: case report and review of the literature. Balkan Med J 28:205–8
8.
Zurück zum Zitat Pizzirusso F, Gillet JP, Fobe D (2004) Isolated spleen metastatic involvement from a colorectal adenocarcinoma complicated with a gastrosplenic fistula A case report and literature review. Acta Chir Belg. 104:214–6CrossRefPubMed Pizzirusso F, Gillet JP, Fobe D (2004) Isolated spleen metastatic involvement from a colorectal adenocarcinoma complicated with a gastrosplenic fistula A case report and literature review. Acta Chir Belg. 104:214–6CrossRefPubMed
10.
Zurück zum Zitat Carolin KA, Prakash SH, Silva YJ (1997) Gastrosplenic fistulas: a case report and review of the literature. Am Surg 63:1007–1010PubMed Carolin KA, Prakash SH, Silva YJ (1997) Gastrosplenic fistulas: a case report and review of the literature. Am Surg 63:1007–1010PubMed
11.
Zurück zum Zitat Bubenik O, Lopez MJ, Greco AO, Kraybill WG, Cherwitz DL (1983) Gastrosplenic fistula following successful chemotherapy for disseminated histiocytic lymphoma. Cancer 52(994):6 Bubenik O, Lopez MJ, Greco AO, Kraybill WG, Cherwitz DL (1983) Gastrosplenic fistula following successful chemotherapy for disseminated histiocytic lymphoma. Cancer 52(994):6
12.
Zurück zum Zitat Kerem M, Sakrak O, Yilmaz TU, Gultekin FA, Dursun A, Bedirli A (2006) Spontaneous gastrosplenic fistula in primary gastric lymphoma: surgical management. Asian J Surg 29:287–290CrossRefPubMed Kerem M, Sakrak O, Yilmaz TU, Gultekin FA, Dursun A, Bedirli A (2006) Spontaneous gastrosplenic fistula in primary gastric lymphoma: surgical management. Asian J Surg 29:287–290CrossRefPubMed
13.
Zurück zum Zitat Choi JE, Chung HJ, Lee HG (2002) Spontaneous gastrosplenic fistula: a rare complication of splenic diffuse large cell lymphoma. Abdom Imaging 27:728–730CrossRefPubMed Choi JE, Chung HJ, Lee HG (2002) Spontaneous gastrosplenic fistula: a rare complication of splenic diffuse large cell lymphoma. Abdom Imaging 27:728–730CrossRefPubMed
14.
Zurück zum Zitat David M, Mahvi and Seth B. Krantz (2012) Stomach. In Textbook of surgery, The biological basis of modern surgical practice. 19th edition. Edited by Courtney M. Townsend, R. Daniel Beauchamp, B. Mark Evers, Kenneth L. Mattox.Philadelphia: Saunders Elsevier; 1182–1226 David M, Mahvi and Seth B. Krantz (2012) Stomach. In Textbook of surgery, The biological basis of modern surgical practice. 19th edition. Edited by Courtney M. Townsend, R. Daniel Beauchamp, B. Mark Evers, Kenneth L. Mattox.Philadelphia: Saunders Elsevier; 1182–1226
15.
Zurück zum Zitat Seib CD, Rocha FG, Hwang DG, Shoji BT (2009) Gastrosplenic fistula from Hodgkin’s lymphoma. J Clin Oncol 10:27 Seib CD, Rocha FG, Hwang DG, Shoji BT (2009) Gastrosplenic fistula from Hodgkin’s lymphoma. J Clin Oncol 10:27
16.
18.
Zurück zum Zitat Aribaş BK, Başkan E, Altinyollar H, Ungül U, Cengız A, Erdıl HF (2008) Gastrosplenic fistula due to splenic large cell lymphoma diagnosed by percutaneous drainage before surgical treatment. Turk J Gastroenterol 19:69–70PubMed Aribaş BK, Başkan E, Altinyollar H, Ungül U, Cengız A, Erdıl HF (2008) Gastrosplenic fistula due to splenic large cell lymphoma diagnosed by percutaneous drainage before surgical treatment. Turk J Gastroenterol 19:69–70PubMed
19.
Zurück zum Zitat Cary ER, Tremaine WJ, Banks PM, Nagorney DM (1989) Isolated Crohn’s disease of the stomach. Mayo Clin Proc 64:776–779CrossRefPubMed Cary ER, Tremaine WJ, Banks PM, Nagorney DM (1989) Isolated Crohn’s disease of the stomach. Mayo Clin Proc 64:776–779CrossRefPubMed
20.
Zurück zum Zitat Abrams JA, Wang TC (2010) From Adenocarcinoma and other tumours of the stomach. In Gastrointestinal and liver disease: pathophysiology/ diagnosis/management. Volume 1. 9th edition. Edited by Mark Feldman, Lawrence S. Friedman, Lawrence J Brandt. Philadelphia: Saunders Elsevier; 887–906 Abrams JA, Wang TC (2010) From Adenocarcinoma and other tumours of the stomach. In Gastrointestinal and liver disease: pathophysiology/ diagnosis/management. Volume 1. 9th edition. Edited by Mark Feldman, Lawrence S. Friedman, Lawrence J Brandt. Philadelphia: Saunders Elsevier; 887–906
21.
Zurück zum Zitat Aviles A, Nambo MJ, Neri N et al (2004) Intensive chemotherapy in the treatment of aggressive diffuse large B-cell lymphoma: malignant lymphoma. Med Oncol 21:269–272CrossRefPubMed Aviles A, Nambo MJ, Neri N et al (2004) Intensive chemotherapy in the treatment of aggressive diffuse large B-cell lymphoma: malignant lymphoma. Med Oncol 21:269–272CrossRefPubMed
22.
Zurück zum Zitat Hiltunen KM, Airo I, Mattila J, Helve O (1991) Massively bleeding gastrosplenic fistula following cytostatic chemotherapy of a malignant lymphoma. J Clin Gastroenterol 13:478–481CrossRefPubMed Hiltunen KM, Airo I, Mattila J, Helve O (1991) Massively bleeding gastrosplenic fistula following cytostatic chemotherapy of a malignant lymphoma. J Clin Gastroenterol 13:478–481CrossRefPubMed
23.
Zurück zum Zitat Moghazy KM (2008) Gastrosplenic fistula following chemotherapy for lymphoma. Gulf J Oncolog 3:64–67 Moghazy KM (2008) Gastrosplenic fistula following chemotherapy for lymphoma. Gulf J Oncolog 3:64–67
24.
Zurück zum Zitat Al-Ashgar HI, Khan MQ, Ghamdi AM, Bamehriz FY, Maghfoor I (2007) Gastrosplenic fistula in Hodgkin’s lymphoma treated successfully by laparoscopic surgery and chemotherapy. Saudi Med J 28:1898–1900PubMed Al-Ashgar HI, Khan MQ, Ghamdi AM, Bamehriz FY, Maghfoor I (2007) Gastrosplenic fistula in Hodgkin’s lymphoma treated successfully by laparoscopic surgery and chemotherapy. Saudi Med J 28:1898–1900PubMed
Metadaten
Titel
A Retrospective Cohort Study of Gastrosplenic Fistula Secondary to Malignant Etiology: Single-Centre Experience of 5 Cases
verfasst von
Poras Chaudhary
Utsav Bhadana
Subhash Chandran
Achint Agarwal
Neeti Kapur
Publikationsdatum
11.08.2022
Verlag
Springer India
Erschienen in
Indian Journal of Surgical Oncology / Ausgabe 1/2023
Print ISSN: 0975-7651
Elektronische ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-022-01615-6

Weitere Artikel der Ausgabe 1/2023

Indian Journal of Surgical Oncology 1/2023 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.