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Pediatric Radiology

Erschienen in:

20.07.2018 | Original Article

A retrospective segmentation analysis of placental volume by magnetic resonance imaging from first trimester to term gestation

verfasst von: Rachel L. León, Kevin T. Li, Brandon P. Brown

Erschienen in: Pediatric Radiology | Ausgabe 13/2018

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Abstract

Background

Abnormalities of the placenta affect 5–7% of pregnancies. Because disturbances in fetal growth are often preceded by dysfunction of the placenta or attenuation of its normal expansion, placental health warrants careful surveillance. There are limited normative data available for placental volume by MRI.

Objective

To determine normative ranges of placental volume by MRI throughout gestation.

Materials and methods

In this cross-sectional retrospective analysis, we reviewed MRI examinations of pregnant females obtained between 2002 and 2017 at a single institution. We performed semi-automated segmentation of the placenta in images obtained in patients with no radiologic evidence of maternal or fetal pathology, using the Philips Intellispace Tumor Tracking Tool.

Results

Placental segmentation was performed in 112 women and had a high degree of interrater reliability (single-measure intraclass correlation coefficient =0.978 with 95% confidence interval [CI] 0.956, 0.989; P<0.001). Normative data on placental volume by MRI increased nonlinearly from 6 weeks to 39 weeks of gestation, with wider variability of placental volume at higher gestational age (GA). We fit placental volumetric data to a polynomial curve of third order described as placental volume = –0.02*GA³ + 1.6*GA² – 13.3*GA + 8.3. Placental volume showed positive correlation with estimated fetal weight (P=0.03) and birth weight (P=0.05).

Conclusion

This study provides normative placental volume by MRI from early first trimester to term gestation. Deviations in placental volume from normal might prove to be an imaging biomarker of adverse fetal health and neonatal outcome, and further studies are needed to more fully understand this metric. Assessment of placental volume should be considered in all routine fetal MRI examinations.

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Titel: A retrospective segmentation analysis of placental volume by magnetic resonance imaging from first trimester to term gestation
verfasst von: Rachel L. León
Kevin T. Li
Brandon P. Brown
Publikationsdatum: 20.07.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Pediatric Radiology / Ausgabe 13/2018
Print ISSN: 0301-0449
Elektronische ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-018-4213-x

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A retrospective segmentation analysis of placental volume by magnetic resonance imaging from first trimester to term gestation

Abstract

Background

Objective

Materials and methods

Results

Conclusion

Neu im Fachgebiet Radiologie

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Wie toxische Männlichkeit der Gesundheit von Männern schadet

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Update Radiologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Background

Objective

Materials and methods

Results

Conclusion

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