nach oben

Lasers in Medical Science

Erschienen in:

17.12.2017 | Review Article

A review of monochromatic light devices for the treatment of alopecia areata

verfasst von: Evan Darwin, Harleen Arora, Penelope A. Hirt, Tongyu Cao Wikramanayake, Joaquin J. Jimenez

Erschienen in: Lasers in Medical Science | Ausgabe 2/2018

Einloggen, um Zugang zu erhalten

Abstract

There are many laser technologies that are being tested that claim to support hair regrowth for patients with alopecia areata (AA). In this paper, we will determine whether the body of evidence supports the use of devices using monochromatic light sources to treat AA. Articles were gathered from PubMed, Embase, and the Cochrane database using these keywords: lasers, excimer laser, low-level laser therapy (LLLT), low-level light therapy, alopecia, alopecia areata, and hair loss with a category modifier of English. Ten clinical trials and seven case reports/abstracts were assessed. Eight clinical trials and two case reports demonstrated hair regrowth with the 308-nm excimer laser/light in men, women, and children. One case report demonstrated hair regrowth with the ALBA 355® laser. One clinical trial and two case reports demonstrated hair regrowth with LLLT. While two case reports demonstrated hair regrowth with fractional laser therapy, one clinical trial showed no improvement. The 308-nm excimer laser is a safe and effective treatment for men, women, and children with refractory AA of the scalp and beard. Larger, double-blinded clinical trials should be conducted to compare excimer laser therapy to standard treatments. More data is needed to determine the efficacy of LLLT and fractional laser therapy in the treatment of AA.

Pratt CH, King LE Jr, Messenger AG, Christiano AM, Sundberg JP (2017) Alopecia areata. Nature Rev Disease Primers 3:17011. https://doi.org/10.1038/nrdp.2017.11 CrossRef

Villasante Fricke AC, Miteva M (2015) Epidemiology and burden of alopecia areata: a systematic review. Clin Cosmet Investig Dermatol 8:397–403. https://doi.org/10.2147/ccid.s53985 PubMedPubMedCentral

Mirzoyev SA, Schrum AG, Davis MDP, Torgerson RR (2014) Lifetime incidence risk of alopecia areata estimated at 2.1 percent by Rochester Epidemiology Project, 1990–2009. J Investigative Dermatology 134(4):1141–1142. https://doi.org/10.1038/jid.2013.464 CrossRef

Hordinsky MK (2013) Overview of alopecia areata. J Investigative Dermatology Symposium Proceedings 16(1):S13–S15. https://doi.org/10.1038/jidsymp.2013.4 CrossRef

Girman CJ, Hartmaier S, Roberts J, Bergfeld W, Waldstreicher J (1999) Patient-perceived importance of negative effects of androgenetic alopecia in women. J Women's Health Gender-Based Medicine 8(8):1091–1095. https://doi.org/10.1089/jwh.1.1999.8.1091 CrossRef

Wells PA, Willmoth T, Russell RJ (1995) Does fortune favour the bald? Psychological correlates of hair loss in males. British J Psychology (London, England : 1953) 86(Pt 3):337–344CrossRef

Charuwichitratana S, Wattanakrai P, Tanrattanakorn S (2000) Randomized double-blind placebo-controlled trial in the treatment of alopecia areata with 0.25% desoximetasone cream. Arch Dermatol 136(10):1276–1277CrossRefPubMed

Kubeyinje EP (1994) Intralesional triamcinolone acetonide in alopecia areata amongst 62 Saudi Arabs. East Afr Med J 71(10):674–675PubMed

Samrao A, Fu JM, Harris ST, Price VH (2013) Bone mineral density in patients with alopecia areata treated with long-term intralesional corticosteroids. J Drugs Dermatology : JDD 12(2):e36–e40

10.

Jahn-Bassler K, Bauer WM, Karlhofer F, Vossen MG, Stingl G (2017) Sequential high- and low-dose systemic corticosteroid therapy for severe childhood alopecia areata. J der Deutschen Dermatologischen Gesellschaft = J German Soc Dermatology : JDDG 15(1):42–47. https://doi.org/10.1111/ddg.12875

11.

Yoshimasu T, Kanazawa N, Yamamoto Y, Furukawa F (2016) Multiple courses of pulse corticosteroid therapy for alopecia areata. J Dermatol 43(9):1075–1077. https://doi.org/10.1111/1346-8138.13388 CrossRefPubMed

12.

Kurosawa M, Nakagawa S, Mizuashi M, Sasaki Y, Kawamura M, Saito M, Aiba S (2006) A comparison of the efficacy, relapse rate and side effects among three modalities of systemic corticosteroid therapy for alopecia areata. Dermatology (Basel, Switzerland) 212(4):361–365. https://doi.org/10.1159/000092287 CrossRef

13.

Happle R (1980) Antigenic competition as a therapeutic concept for alopecia areata. Arch Dermatol Res 267(1):109–114CrossRefPubMed

14.

Taylor CR, Hawk JL (1995) PUVA treatment of alopecia areata partialis, totalis and universalis: audit of 10 years experience at St John’s Institute of Dermatology. Br J Dermatol 133(6):914–918CrossRefPubMed

15.

Gupta AK, Carviel J, Abramovits W (2017) Treating alopecia areata: current practices versus new directions. Am J Clin Dermatol 18(1):67–75. https://doi.org/10.1007/s40257-016-0230-4 CrossRefPubMed

16.

Zakaria W, Passeron T, Ostovari N, Lacour JP, Ortonne JP (2004) 308-nm excimer laser therapy in alopecia areata. J Am Acad Dermatol 51(5):837–838. https://doi.org/10.1016/j.jaad.2004.05.026 CrossRefPubMed

17.

Aubin F, Vigan M, Puzenat E, Blanc D, Drobacheff C, Deprez P, Humbert P, Laurent R (2005) Evaluation of a novel 308-nm monochromatic excimer light delivery system in dermatology: a pilot study in different chronic localized dermatoses. Br J Dermatol 152(1):99–103. https://doi.org/10.1111/j.1365-2133.2005.06320.x CrossRefPubMed

18.

Al-Mutairi N (2007) 308-nm excimer laser for the treatment of alopecia areata. Dermatologic surgery : Official Publication Am Soc Dermatologic Surgery (et al) 33 (12):1483–1487. doi:https://doi.org/10.1111/j.1524-4725.2007.33320.x

19.

Al-Mutairi N (2009) 308-nm excimer laser for the treatment of alopecia areata in children. Pediatr Dermatol 26 (5):547–550. doi:https://doi.org/10.1111/j.1525-1470.2009.00980.x

20.

Nistico SP, Saraceno R, Schipani C, Costanzo A, Chimenti S (2009) Different applications of monochromatic excimer light in skin diseases. Photomed Laser Surg 27(4):647–654. https://doi.org/10.1089/pho.2008.2317 CrossRefPubMed

21.

Ohtsuki A, Hasegawa T, Komiyama E, Takagi A, Kawasaki J, Ikeda S (2013) 308-nm excimer lamp for the treatment of alopecia areata: clinical trial on 16 cases. Indian J Dermatology 58(4):326. https://doi.org/10.4103/0019-5154.113954 CrossRef

22.

Byun JW, Moon JH, Bang CY, Shin J, Choi GS (2015) Effectiveness of 308-nm excimer laser therapy in treating alopecia areata, determined by examining the treated sides of selected alopecic patches. Dermatology (Basel, Switzerland) 231(1):70–76. https://doi.org/10.1159/000381912 CrossRef

23.

Arakawa Y, Nomiyama T, Katoh N (2016) Three hundred and eight nanometer excimer light therapy for alopecia universalis that is resistant to other treatments: a clinical study of 11 patients. J Dermatol 43(12):1412–1416. https://doi.org/10.1111/1346-8138.13419 CrossRefPubMed

24.

Waiz M, Saleh AZ, Hayani R, Jubory SO (2006) Use of the pulsed infrared diode laser (904 nm) in the treatment of alopecia areata. J Cosmetic Laser Therapy : Official Publication European Soc Laser Dermatology 8(1):27–30. https://doi.org/10.1080/14764170600607368 CrossRef

25.

Yalici-Armagan B, Elcin G (2016) The effect of neodymium: yttrium aluminum garnet and fractional carbon dioxide lasers on alopecia areata: a prospective controlled clinical trial. Dermatologic Surgery: Official Publication Am Soc Dermatologic Surgery (et al) 42 (4):500–506. doi:https://doi.org/10.1097/dss.0000000000000649

26.

de Gruijl FR (2017) UV adaptation: pigmentation and protection against overexposure. Exp Dermatol 26(7):557–562. https://doi.org/10.1111/exd.13332

27.

Gundogan C, Greve B, Raulin C (2004) Treatment of alopecia areata with the 308-nm xenon chloride excimer laser: case report of two successful treatments with the excimer laser. Lasers Surg Med 34(2):86–90. https://doi.org/10.1002/lsm.20002 CrossRefPubMed

28.

Ohtsuki A, Hasegawa T, Ikeda S (2010) Treatment of alopecia areata with 308-nm excimer lamp. J Dermatol 37(12):1032–1035. https://doi.org/10.1111/j.1346-8138.2010.00942.x CrossRefPubMed

29.

D'Erme AM, Lotti T (2013) Uva1 laser (ALBA 355®) for alopecia areata. Lasers Med Sci 28(6):1426. https://doi.org/10.1007/s10103-013-1431-1

30.

Carvalho Leite Júnior A, Padovez F (2013) Low-level laser therapy for alopecia areata-case relate. J Investig Dermatol 133(5):1407. https://doi.org/10.1038/jid.2013.110

31.

Rogers N (2013) Case report: low-level laser treatment accelerated hair regrowth in human with alopecia areata. Lasers Surg Med 45(4):273. https://doi.org/10.1002/lsm.22138

32.

Yoo KH, Kim MN, Kim BJ, Kim CW (2010) Treatment of alopecia areata with fractional photothermolysis laser. Int J Dermatol 49(7):845–847. https://doi.org/10.1111/j.1365-4632.2009.04230.x PubMed

33.

Tsai YC (2016) Alopecia areata treated with fractional photothermolysis laser: a case report. J Am Acad Dermatol 74(5):AB132

34.

Mehraban S, Feily A (2014) 308-nm excimer laser in dermatology. J lasers Medical Sci 5(1):8–12

35.

Kagen M, Cao LY, Oyetakin-White P, Tacastacas JD, Yan C, TS MC, Cooper KD (2012) Single administration of lesion-limited high-dose (TURBO) ultraviolet B using the excimer laser: clinical clearing in association with apoptosis of epidermal and dermal T cell subsets in psoriasis. Photodermatology, Photoimmunology Photomedicine 28(6):293–298. https://doi.org/10.1111/j.1600-0781.2012.00692.x CrossRefPubMed

36.

Bulat V, Situm M, Dediol I, Ljubicic I, Bradic L (2011) The mechanisms of action of phototherapy in the treatment of the most common dermatoses. Collegium Antropologicum 35(Suppl 2):147–151PubMed

37.

Ito T (2012) Advances in the management of alopecia areata. J Dermatol 39(1):11–17. https://doi.org/10.1111/j.1346-8138.2011.01476.x CrossRefPubMed

38.

GoodRx (2017) Desoximetasone. Goodrx. https://www.goodrx.com/desoximetasone. Accessed 29 Mar 2017

39.

Jimenez JJ, Wikramanayake TC, Bergfeld W, Hordinsky M, Hickman JG, Hamblin MR, Schachner LA (2014) Efficacy and safety of a low-level laser device in the treatment of male and female pattern hair loss: a multicenter, randomized, sham device-controlled, double-blind study. Am J Clin Dermatol 15(2):115–127. https://doi.org/10.1007/s40257-013-0060-6 CrossRefPubMedPubMedCentral

40.

Eells JT, Wong-Riley MT, VerHoeve J, Henry M, Buchman EV, Kane MP, Gould LJ, Das R, Jett M, Hodgson BD, Margolis D, Whelan HT (2004) Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy. Mitochondrion 4(5–6):559–567. https://doi.org/10.1016/j.mito.2004.07.033 CrossRefPubMed

41.

Pastore D, Greco M, Passarella S (2000) Specific helium-neon laser sensitivity of the purified cytochrome c oxidase. Int J Radiat Biol 76(6):863–870CrossRefPubMed

42.

Lubart R, Eichler M, Lavi R, Friedman H, Shainberg A (2005) Low-energy laser irradiation promotes cellular redox activity. Photomed Laser Surg 23(1):3–9. https://doi.org/10.1089/pho.2005.23.3 CrossRefPubMed

43.

Sakurai Y, Yamaguchi M, Abiko Y (2000) Inhibitory effect of low-level laser irradiation on LPS-stimulated prostaglandin E2 production and cyclooxygenase-2 in human gingival fibroblasts. Eur J Oral Sci 108(1):29–34CrossRefPubMed

44.

Arany PR, Nayak RS, Hallikerimath S, Limaye AM, Kale AD, Kondaiah P (2007) Activation of latent TGF-beta1 by low-power laser in vitro correlates with increased TGF-beta1 levels in laser-enhanced oral wound healing. Wound Repair Regeneration: Official Publication Wound Healing Soc European Tissue Repair Soc 15(6):866–874. https://doi.org/10.1111/j.1524-475X.2007.00306.x CrossRef

45.

de Lima FM, Villaverde AB, Albertini R, Correa JC, Carvalho RL, Munin E, Araujo T, Silva JA, Aimbire F (2011) Dual effect of low-level laser therapy (LLLT) on the acute lung inflammation induced by intestinal ischemia and reperfusion: action on anti- and pro-inflammatory cytokines. Lasers Surg Med 43(5):410–420. https://doi.org/10.1002/lsm.21053 CrossRefPubMed

46.

Paasch U (2016) The future of fractional lasers. Facial Plastic Surgery: FPS 32(3):261–268. https://doi.org/10.1055/s-0036-1584215 CrossRefPubMed

47.

Huang Y, Zhuo F, Li L (2017) Enhancing hair growth in male androgenetic alopecia by a combination of fractional CO2 laser therapy and hair growth factors. Lasers Med Sci 32(8):1711–1718. https://doi.org/10.1007/s10103-017-2232-8

48.

Ito M, Yang Z, Andl T, Cui C, Kim N, Millar SE, Cotsarelis G (2007) Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Nature 447(7142):316–320. https://doi.org/10.1038/nature05766 CrossRefPubMed

49.

Zerbinati N, Portale S, Palmieri B, Rottigni V, Iannitti T (2012) A preliminary study to assess the efficacy of a new UVA1 laser for treatment of psoriasis. Photomed Laser Surg 30(10):610–614. https://doi.org/10.1089/pho.2012.3281 CrossRefPubMed

50.

Godar DE (1999) UVA1 radiation triggers two different final apoptotic pathways. J Investigative Dermatology 112(1):3–12. https://doi.org/10.1046/j.1523-1747.1999.00474.x CrossRef

Titel: A review of monochromatic light devices for the treatment of alopecia areata
verfasst von: Evan Darwin
Harleen Arora
Penelope A. Hirt
Tongyu Cao Wikramanayake
Joaquin J. Jimenez
Publikationsdatum: 17.12.2017
Verlag: Springer London
Erschienen in: Lasers in Medical Science / Ausgabe 2/2018
Print ISSN: 0268-8921
Elektronische ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-017-2412-6

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2018

Outpatient erbium:YAG (2940 nm) laser treatment for snoring: a prospective study on 40 patients

Randomized, blinded, controlled trial on effectiveness of photobiomodulation therapy and exercise training in the fibromyalgia treatment

Dose-response effect of photobiomodulation therapy on neuromuscular economy during submaximal running

Low-level laser therapy prevents endothelial cells from TNF-α/cycloheximide-induced apoptosis

Combination of MPPa-PDT and HSV1-TK/GCV gene therapy on prostate cancer

Cardiac autonomic responses and number of repetitions maximum after LED irradiation in the ipsilateral and contralateral lower limb