Skip to main content
Erschienen in: Techniques in Coloproctology 1/2017

19.12.2016 | Original Article

A simple web-based risk calculator (www.anastomoticleak.com) is superior to the surgeon’s estimate of anastomotic leak after colon cancer resection

verfasst von: T. Sammour, M. Lewis, M. L. Thomas, M. J. Lawrence, A. Hunter, J. W. Moore

Erschienen in: Techniques in Coloproctology | Ausgabe 1/2017

Einloggen, um Zugang zu erhalten

Abstract

Background

Anastomotic leak can be a devastating complication, and early prediction is difficult. The aim of this study is to prospectively validate a simple anastomotic leak risk calculator and compare its predictive value with the estimate of the primary operating surgeon.

Methods

Consecutive patients undergoing elective or emergency colon cancer surgery with a primary anastomosis over a 1-year period were prospectively included. A recently published anastomotic leak risk nomogram was converted to an online calculator (www.​anastomoticleak.​com). The calculator-derived risk of anastomotic leak and the risk estimated by the primary operating surgeon were recorded at the completion of surgery. The primary outcome was anastomotic leak within 90 days as defined by previously published criteria. Area under receiver operating characteristic curve analysis (AUROC) was performed for both risk estimates.

Results

A total of 105 patients were screened for inclusion during the study period, of whom 83 met the inclusion criteria. The overall anastomotic leak rate was 9.6%. The anastomotic leak calculator was highly predictive of anastomotic leak (AUROC 0.84, P = 0.002), whereas the surgeon estimate was not predictive (AUROC 0.40, P = 0.243).

Conclusions

A simple anastomotic leak risk calculator is significantly better at predicting anastomotic leak than the estimate of the primary surgeon. Further external validation on a larger data set is required.
Literatur
1.
Zurück zum Zitat Nachiappan S, Askari A, Malietzis G et al (2015) The impact of anastomotic leak and its treatment on cancer recurrence and survival following elective colorectal cancer resection. World J Surg 39:1052–1058CrossRefPubMed Nachiappan S, Askari A, Malietzis G et al (2015) The impact of anastomotic leak and its treatment on cancer recurrence and survival following elective colorectal cancer resection. World J Surg 39:1052–1058CrossRefPubMed
2.
Zurück zum Zitat Midura EF, Hanseman D, Davis BR et al (2015) Risk factors and consequences of anastomotic leak after colectomy: a national analysis. Dis Colon Rectum 58:333–338CrossRefPubMed Midura EF, Hanseman D, Davis BR et al (2015) Risk factors and consequences of anastomotic leak after colectomy: a national analysis. Dis Colon Rectum 58:333–338CrossRefPubMed
3.
Zurück zum Zitat Nachiappan S, Faiz O (2015) Anastomotic leak increases distant recurrence and long-term mortality after curative resection for colonic cancer. Ann Surg 262:e111CrossRefPubMed Nachiappan S, Faiz O (2015) Anastomotic leak increases distant recurrence and long-term mortality after curative resection for colonic cancer. Ann Surg 262:e111CrossRefPubMed
4.
Zurück zum Zitat Bakker IS, Grossmann I, Henneman D, Havenga K, Wiggers T (2014) Risk factors for anastomotic leakage and leak-related mortality after colonic cancer surgery in a nationwide audit. Br J Surg 101:424–432 (discussion 432) CrossRefPubMed Bakker IS, Grossmann I, Henneman D, Havenga K, Wiggers T (2014) Risk factors for anastomotic leakage and leak-related mortality after colonic cancer surgery in a nationwide audit. Br J Surg 101:424–432 (discussion 432) CrossRefPubMed
5.
Zurück zum Zitat Kingham TP, Pachter HL (2009) Colonic anastomotic leak: risk factors, diagnosis, and treatment. J Am Coll Surg 208:269–278CrossRefPubMed Kingham TP, Pachter HL (2009) Colonic anastomotic leak: risk factors, diagnosis, and treatment. J Am Coll Surg 208:269–278CrossRefPubMed
6.
Zurück zum Zitat Ziegler MA, Catto JA, Riggs TW, Gates ER, Grodsky MB, Wasvary HJ (2012) Risk factors for anastomotic leak and mortality in diabetic patients undergoing colectomy: analysis from a statewide surgical quality collaborative. Arch Surg 147:600–605CrossRefPubMed Ziegler MA, Catto JA, Riggs TW, Gates ER, Grodsky MB, Wasvary HJ (2012) Risk factors for anastomotic leak and mortality in diabetic patients undergoing colectomy: analysis from a statewide surgical quality collaborative. Arch Surg 147:600–605CrossRefPubMed
7.
Zurück zum Zitat Frasson M, Flor-Lorente B, Rodriguez JL et al (2015) Risk factors for anastomotic leak after colon resection for cancer: multivariate analysis and nomogram from a multicentric, prospective, national study with 3193 patients. Ann Surg 262:321–330CrossRefPubMed Frasson M, Flor-Lorente B, Rodriguez JL et al (2015) Risk factors for anastomotic leak after colon resection for cancer: multivariate analysis and nomogram from a multicentric, prospective, national study with 3193 patients. Ann Surg 262:321–330CrossRefPubMed
8.
Zurück zum Zitat Buzby GP, Knox LS, Crosby LO et al (1988) Study protocol: a randomized clinical trial of total parenteral nutrition in malnourished surgical patients. Am J Clin Nutr 47(2 Suppl):366–381PubMed Buzby GP, Knox LS, Crosby LO et al (1988) Study protocol: a randomized clinical trial of total parenteral nutrition in malnourished surgical patients. Am J Clin Nutr 47(2 Suppl):366–381PubMed
9.
Zurück zum Zitat Clavien PA, Barkun J, de Oliveira ML et al (2009) The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg 250:187–196CrossRefPubMed Clavien PA, Barkun J, de Oliveira ML et al (2009) The Clavien–Dindo classification of surgical complications: five-year experience. Ann Surg 250:187–196CrossRefPubMed
10.
Zurück zum Zitat Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Crebbin W, Beasley SW, Watters DA (2013) Clinical decision making: how surgeons do it. ANZ J Surg 83:422–428CrossRefPubMed Crebbin W, Beasley SW, Watters DA (2013) Clinical decision making: how surgeons do it. ANZ J Surg 83:422–428CrossRefPubMed
14.
Zurück zum Zitat Clavien PA, Dindo D (2007) Surgeon’s intuition: is it enough to assess patients’ surgical risk? World J Surg 31:1909–1911CrossRefPubMed Clavien PA, Dindo D (2007) Surgeon’s intuition: is it enough to assess patients’ surgical risk? World J Surg 31:1909–1911CrossRefPubMed
15.
Zurück zum Zitat Pauley K, Flin R, Yule S, Youngson G (2011) Surgeons’ intraoperative decision making and risk management. Am J Surg 202:375–381CrossRefPubMed Pauley K, Flin R, Yule S, Youngson G (2011) Surgeons’ intraoperative decision making and risk management. Am J Surg 202:375–381CrossRefPubMed
16.
Zurück zum Zitat Sevdalis N, Jacklin R (2008) Opening the “black box” of surgeons’ risk estimation: from intuition to quantitative modeling. World J Surg 32:324–325 (author reply 326–327) CrossRefPubMed Sevdalis N, Jacklin R (2008) Opening the “black box” of surgeons’ risk estimation: from intuition to quantitative modeling. World J Surg 32:324–325 (author reply 326–327) CrossRefPubMed
17.
Zurück zum Zitat Woodfield JC, Pettigrew RA, Plank LD, Landmann M, van Rij AM (2007) Accuracy of the surgeons’ clinical prediction of perioperative complications using a visual analog scale. World J Surg 31:1912–1920CrossRefPubMed Woodfield JC, Pettigrew RA, Plank LD, Landmann M, van Rij AM (2007) Accuracy of the surgeons’ clinical prediction of perioperative complications using a visual analog scale. World J Surg 31:1912–1920CrossRefPubMed
18.
Zurück zum Zitat Farges O, Vibert E, Cosse C et al (2014) “Surgeons’ intuition” versus “prognostic models”: predicting the risk of liver resections. Ann Surg 260:923–928 (discussion 928–930) CrossRefPubMed Farges O, Vibert E, Cosse C et al (2014) “Surgeons’ intuition” versus “prognostic models”: predicting the risk of liver resections. Ann Surg 260:923–928 (discussion 928–930) CrossRefPubMed
19.
Zurück zum Zitat Erb L, Hyman NH, Osler T (2014) Abnormal vital signs are common after bowel resection and do not predict anastomotic leak. J Am Coll Surg 218:1195–1199CrossRefPubMed Erb L, Hyman NH, Osler T (2014) Abnormal vital signs are common after bowel resection and do not predict anastomotic leak. J Am Coll Surg 218:1195–1199CrossRefPubMed
20.
Zurück zum Zitat Daams F, Wu Z, Lahaye MJ, Jeekel J, Lange JF (2014) Prediction and diagnosis of colorectal anastomotic leakage: a systematic review of literature. World J Gastrointest Surg 6:14–26CrossRefPubMedPubMedCentral Daams F, Wu Z, Lahaye MJ, Jeekel J, Lange JF (2014) Prediction and diagnosis of colorectal anastomotic leakage: a systematic review of literature. World J Gastrointest Surg 6:14–26CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Tevis SE, Carchman EH, Foley EF, Heise CP, Harms BA, Kennedy GD (2015) Does anastomotic leak contribute to high failure-to-rescue rates? Ann Surg 263:1148–1151CrossRef Tevis SE, Carchman EH, Foley EF, Heise CP, Harms BA, Kennedy GD (2015) Does anastomotic leak contribute to high failure-to-rescue rates? Ann Surg 263:1148–1151CrossRef
Metadaten
Titel
A simple web-based risk calculator (www.anastomoticleak.com) is superior to the surgeon’s estimate of anastomotic leak after colon cancer resection
verfasst von
T. Sammour
M. Lewis
M. L. Thomas
M. J. Lawrence
A. Hunter
J. W. Moore
Publikationsdatum
19.12.2016
Verlag
Springer International Publishing
Erschienen in
Techniques in Coloproctology / Ausgabe 1/2017
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-016-1567-7

Weitere Artikel der Ausgabe 1/2017

Techniques in Coloproctology 1/2017 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.