Skip to main content
main-content

01.12.2014 | Research article | Ausgabe 1/2014 Open Access

The Journal of Headache and Pain 1/2014

A systematic review of causes of sudden and severe headache (Thunderclap Headache): should lists be evidence based?

Zeitschrift:
The Journal of Headache and Pain > Ausgabe 1/2014
Autoren:
Emma Devenney, Hazel Neale, Raeburn B Forbes
Wichtige Hinweise

Competing interests

RF has received unrestricted educational grants to fund attendance at European Neurological Society meeting in Athens 2004 (value <1000GBP), The International Headache Society Meeting in Stockholm 2007 (value <1000GBP) and The American Headache Society Meeting Boston June 2008 (value <2000GBP), The EHMTIC meeting London 2012 (value <1000GBP) from Janssen-Cilag and Allergan pharmaceutical companies. The Neurology Department in which RF practices received an unrestricted educational grant from Cyberonics for an economic analysis of vagus nerve stimulators in 2007 (value 7000GBP). RF has received an honorarium for contributions at an educational meeting sponsored by Allergan in Dublin November 2013 (1065GBP). RF runs a website called severe-headache-expert.com which earns income from advertising. HN no conflicts of interest. ED no conflicts of interest.

Authors’ contributions

RF initiated and designed the review, screened the articles, assisted with data abstraction, data analysis, co-wrote and edited and approved the final manuscript, and is ultimately accountable for this work. HN designed the systematic review and obtained articles from external sources. ED abstracted data from identified articles, summarized and analysed data, wrote initial version of manuscript and approved final version for submission. All authors read and approved the final manuscript.

Abstract

Background

There are many potential causes of sudden and severe headache (thunderclap headache), the most important of which is aneurysmal subarachnoid haemorrhage. Published academic reviews report a wide range of causes. We sought to create a definitive list of causes, other than aneurysmal subarachnoid haemorrhage, using a systematic review.

Methods

Systematic Review of EMBASE and MEDLINE databases using pre-defined search criteria up to September 2009. We extracted data from any original research paper or case report describing a case of someone presenting with a sudden and severe headache, and summarized the published causes.

Results

Our search identified over 21,000 titles, of which 1224 articles were scrutinized in full. 213 articles described 2345 people with sudden and severe headache, and we identified 6 English language academic review articles. A total of 119 causes were identified, of which 46 (38%) were not mentioned in published academic review articles. Using capture-recapture analysis, we estimate that our search was 98% complete. There is only one population-based estimate of the incidence of sudden and severe headache at 43 cases per 100,000. In cohort studies, the most common causes identified were primary headaches or headaches of uncertain cause. Vasoconstriction syndromes are commonly mentioned in case reports or case series. The most common cause not mentioned in academic reviews was pneumocephalus. 70 non-English language articles were identified but these did not contain additional causes.

Conclusions

There are over 100 different published causes of sudden and severe headache, other than aneurysmal subarachnoid haemorrhage. We have now made a definitive list of causes for future reference which we intend to maintain. There is a need for an up to date population based description of cause of sudden and severe headache as the modern epidemiology of thunderclap headache may require updating in the light of research on cerebral vasoconstriction syndromes.
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 1/2014

The Journal of Headache and Pain 1/2014 Zur Ausgabe

Neu im Fachgebiet AINS

Meistgelesene Bücher aus dem Fachgebiet AINS

  • 2014 | Buch

    Komplikationen in der Anästhesie

    Fallbeispiele Analyse Prävention

    Aus Fehlern lernen und dadurch Zwischenfälle vermeiden! Komplikationen oder Zwischenfälle in der Anästhesie können für Patienten schwerwiegende Folgen haben. Häufig sind sie eine Kombination menschlicher, organisatorischer und technischer Fehler.

    Herausgeber:
    Matthias Hübler, Thea Koch
  • 2013 | Buch

    Anästhesie Fragen und Antworten

    1655 Fakten für die Facharztprüfung und das Europäische Diplom für Anästhesiologie und Intensivmedizin (DESA)

    Mit Sicherheit erfolgreich in Prüfung und Praxis! Effektiv wiederholen und im entscheidenden Moment die richtigen Antworten parat haben - dafür ist dieses beliebte Prüfungsbuch garantiert hilfreich. Anhand der Multiple-Choice-Fragen ist die optimale Vorbereitung auf das Prüfungsprinzip der D.E.A.A. gewährleistet.

    Autoren:
    Prof. Dr. Franz Kehl, Dr. Hans-Joachim Wilke
  • 2011 | Buch

    Pharmakotherapie in der Anästhesie und Intensivmedizin

    Wie und wieso wirken vasoaktive Substanzen und wie werden sie wirksam eingesetzt Welche Substanzen eignen sich zur perioperativen Myokardprojektion? 
    Kenntnisse zur Pharmakologie und deren Anwendung sind das notwendige Rüstzeug für den Anästhesisten und Intensivmediziner. Lernen Sie von erfahrenen Anästhesisten und Pharmakologen.

    Herausgeber:
    Prof. Dr. Peter H. Tonner, Prof. Dr. Lutz Hein
  • 2019 | Buch

    Anästhesie und Intensivmedizin - Prüfungswissen für die Fachpflege

    Egal ob Teilnehmer der Fachweiterbildung oder langjähriger Mitarbeiter: Mit diesem Arbeitsbuch können Sie alle Fakten der Intensivmedizin und Anästhesie für die Fachpflege gezielt überprüfen, vertiefen und festigen. Multiple-Choice-Fragen …

    Autor:
    Reinhard Larsen

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update AINS und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise