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Erschienen in: Clinical and Translational Oncology 2/2014

01.02.2014 | Review Article

A ‘tête-à tête’ between cancer stem cells and endothelial progenitor cells in tumor angiogenesis

verfasst von: S. Kaur, P. Bajwa

Erschienen in: Clinical and Translational Oncology | Ausgabe 2/2014

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Abstract

Accumulating evidence suggests the involvement of stem cells in tumor angiogenesis. Two major types of stem cells frequently discussed in this regard are bone marrow-derived endothelial progenitor cells (EPCs) and tumor-derived cancer stem cells (CSCs). The present review discusses the possibility of a close association between these two cell types that drives the tumor towards metastasis. An exploration of this plausible relationship between EPCs and CSCs is imperative to completely unveil the mechanisms of tumor angiogenesis and develop CSC- and/or EPC-targeted anti-tumor therapies.
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Metadaten
Titel
A ‘tête-à tête’ between cancer stem cells and endothelial progenitor cells in tumor angiogenesis
verfasst von
S. Kaur
P. Bajwa
Publikationsdatum
01.02.2014
Verlag
Springer Milan
Erschienen in
Clinical and Translational Oncology / Ausgabe 2/2014
Print ISSN: 1699-048X
Elektronische ISSN: 1699-3055
DOI
https://doi.org/10.1007/s12094-013-1103-4

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