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21.05.2022 | Original Paper

“A Theta Burst Stimulation on Pre-SMA: Proof-of-Concept of Transcranial Magnetic Stimulation in Gambling Disorder”

verfasst von: Luana Salerno, Eleonora Grassi, Nikos Makris, Stefano Pallanti

Erschienen in: Journal of Gambling Studies | Ausgabe 4/2022

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Abstract

Gambling Disorder (GD) is a condition constituting a public health concern, with a burden of harm which is much greater than that of drug addiction. Patients with GD are generally reluctant to pharmacologic treatment and seem to prefer nonpharmacological interventions. Therefore, this proof-of-concept study aimed to investigate the feasibility of continuous Theta Burst Stimulation (cTBS) on the pre-SMA in six patients (5 males, 1 female), aged 30–64 years, with a DSM-5 diagnosis of Gambling Disorder and no comorbid mood disorders. Participants received over 10 sessions of Continuous TBS (cTBS) over pre-SMA bilaterally and have been evaluated using rating scales, including the PG-YBOCS and the CGI, before treatment (T0), at day 10 of treatment (T1) and at day 30 after treatment (T2); cTBS intervention was safe and without side effects. Since the design of our study does not allow us to draw conclusions on the effectiveness of the intervention with respect to the improvement of the functioning of the subject with GD, a more in-depth study, including a sham condition, neurocognitive measures of disinhibition and decision making, and collecting follow-up data on the sustained effect of TBS over a longer period is ongoing.

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Titel: “A Theta Burst Stimulation on Pre-SMA: Proof-of-Concept of Transcranial Magnetic Stimulation in Gambling Disorder”
verfasst von: Luana Salerno
Eleonora Grassi
Nikos Makris
Stefano Pallanti
Publikationsdatum: 21.05.2022
Verlag: Springer US
Erschienen in: Journal of Gambling Studies / Ausgabe 4/2022
Elektronische ISSN: 1573-3602
DOI: https://doi.org/10.1007/s10899-022-10129-3

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Springer Medizin

“A Theta Burst Stimulation on Pre-SMA: Proof-of-Concept of Transcranial Magnetic Stimulation in Gambling Disorder”

Abstract

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