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Erschienen in: Pediatric Nephrology 10/2018

26.02.2018 | Clinical Quiz

A young child with fever and unexplained acute kidney injury: Answers

verfasst von: Sidharth Kumar Sethi, Arushi Nautiyal, Alka Rana, Rajan Duggal, Ashish Nandwani, Dinesh Yadav, Amit Mahapatra, Maninder Dhaliwal, Veena Raghunathan, Shyam Bihari Bansal

Erschienen in: Pediatric Nephrology | Ausgabe 10/2018

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Excerpt

1.
Acute kidney injury as a direct consequence of hemophagocytic lymphohistiocytosis [HLH]. CD68 positivity signifies histiocytic infiltrate. Few histiocytes also showed lymphocytic phagocytosis.
 
2.
To find the cause of HLH, all infectious etiologies (e.g. typhus, malaria, dengue), malignancy and genetic sequencing to rule out primary HLH
 
3.
Pulse steroids followed by oral prednisolone in view of predominant histiocytic infiltrate with tubulointerstitial nephritis
 
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Metadaten
Titel
A young child with fever and unexplained acute kidney injury: Answers
verfasst von
Sidharth Kumar Sethi
Arushi Nautiyal
Alka Rana
Rajan Duggal
Ashish Nandwani
Dinesh Yadav
Amit Mahapatra
Maninder Dhaliwal
Veena Raghunathan
Shyam Bihari Bansal
Publikationsdatum
26.02.2018
Verlag
Springer Berlin Heidelberg
Erschienen in
Pediatric Nephrology / Ausgabe 10/2018
Print ISSN: 0931-041X
Elektronische ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-018-3911-9

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