Erschienen in:
08.03.2016 | Bone and Soft Tissue Sarcomas
Abdominal Desmoid Tumors: Hands Off?
verfasst von:
Danique L. M. van Broekhoven, MD, Dirk J. Grunhagen, MD, PhD, Cornelis Verhoef, MD, PhD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 7/2016
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Excerpt
The reported incidence of desmoid tumors (DT) seems to increase from about two cases per million people in 1993 to about five cases per million people in 2013.
1 Because it lacks the ability to metastasize, a desmoid tumor is classified as a benign disorder. Nevertheless, the sequelae of this disease and the applied treatments may be underlined by the fact that patients with familial adenomatous polyposis (FAP) may die from the consequences of DT. Moreover, substantial morbidity due to invasive growth is frequently seen. Because of the poor understanding of the natural history of the disease, its tumor biology, and the lack of randomized studies comparing different treatment options, the recommended treatment options vary widely depending on tumor aggressiveness, location, patient wish, and preferences of the treating physicians. …
