Background
Methods
Study subjects
Study protocol
MIBI SPECT myocardial perfusion imaging
MIBI SPECT image interpretation
Echocardiography
11C-acetate positron emission tomography
11C-acetate PET data analysis
Statistical analysis
Results
Baseline patient characteristics
Characteristic | All patients (n = 18) |
---|---|
Age, years | 69.2 ± 8.7 |
Male | 10 (56 %) |
Culprit region | |
LAD | 9 (50 %) |
LCx | 2 (11 %) |
RCA | 7 (39 %) |
Time from onset to revascularization, h | 5.4 ± 6.8 |
Revascularization method, n (%) | |
Stent | 18 (100 %) |
Peak creatine kinase, IU/L | 1697.6 ± 1522.5 |
Coronary risk factor, n (%) | |
Hypertension | 9 (50 %) |
Diabetes mellitus | 5 (28 %) |
Dyslipidemia | 10 (56 %) |
Smoking history | 9 (50 %) |
Past history | |
Pacemaker implantation | 1 (6 %) |
Post PCI | 1 (6 %) |
Hemodynamics | |
Systolic blood pressure, mmHg | 122.7 ± 14.9 |
Diastolic blood pressure, mmHg | 62.3 ± 9.9 |
Heart rate, beats per min | 63.3 ± 9.2 |
Echocardiography data | |
LVEF, % | 56.5 ± 9.5 |
Interventricular septal wall thickness, mm (range) | 10.4 ± 1.9 (7–16) |
Posterior wall thickness, mm (range) | 9.2 ± 1.1 (7–12) |
Pt | Culprit vessel | LVH | Peak CK (IU/L) | Time from onset to revascularization (h) | Accelerated MIBI clearance in the culprit region |
---|---|---|---|---|---|
1 | RCA | No | 374 | 2.4 | No |
2 | LCx | Yes | 268 | NA | No |
3 | RCA | No | 853 | 5.0 | No |
4 | RCA | No | 1550 | 5.0 | Yes |
5 | LAD | Yes | 612 | NA | Yes |
6 | LAD | Yes | 4189 | 5.0 | No |
7 | RCA | No | 1943 | 1.5 | Yes |
8 | LAD | Yes | 1133 | 4.2 | No |
9 | LAD | No | 4874 | 3.0 | Yes |
10 | LAD | Yes | 5056 | 3.0 | Yes |
11 | LAD | Yes | 952 | NA | Yes |
12 | LAD | No | 969 | 1.0 | No |
13 | RCA | Yes | 2040 | 4.0 | Yes |
14 | RCA | No | 2415 | 4.5 | Yes |
15 | LCx | Yes | 112 | NA | No |
16 | LAD | No | 617 | 3.0 | Yes |
17 | RCA | No | 1411 | 28.5 | Yes |
18 | LAD | No | 1188 | 6.0 | No |
Echocardiography findings
MIBI SPECT findings
Segment numbers | Early image | Delayed image |
p value |
---|---|---|---|
Group N (n = 64) | 0.03 ± 0.12 | 0.04 ± 0.14 | 0.32 |
Group AC (n = 14) | 0.75 ± 0.87 | 1.96 ± 0.89 | <0.001 |
Group F (n = 17) | 2.15 ± 0.77 | 2.18 ± 0.77 | 0.33 |
Segment numbers | Early image, % | Delayed image, % |
p value |
---|---|---|---|
Group N (n = 61) | 71.4 ± 13.0 | 70.2 ± 12.5 | 0.047 |
Group AC (n = 14) | 61.1 ± 12.3 | 57.9 ± 13.0 | 0.08 |
Group F (n = 15) | 53.7 ± 10.8 | 48.1 ± 10.7 | <0.001 |
Segment numbers | Percent change of percentage peak uptake |
---|---|
Group N (n = 61) | −1.2 ± 5.4 |
Group AC (n = 14) | −3.2 ± 5.9 |
Group F (n = 15) | −5.6 ± 4.2* |