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Clinical and Experimental Nephrology

Erschienen in:

05.02.2016 | Commentary

Accurate estimation of protein/creatinine ratio on urine sample in CKD patients

verfasst von: Kensei Taguchi, Seiji Ueda, Kei Fukami

Erschienen in: Clinical and Experimental Nephrology | Ausgabe 3/2016

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Excerpt

Chronic kidney diseases (CKD) is common in general population and is associated with increased risk for end stage renal disease (ESRD), its complications and mortality. The number of patients with ESRD requiring maintenance dialysis or transplantation is increasing worldwide and the costs associated with the care of those are estimated to exceed US$1 trillion. Therefore, the discovery of novel and accurate biomarker for evaluating the risk of CKD patients is needed. So far, proteinuria and/or albuminuria are widely recognized as a pivotal predictor of risk for the development and progression of CKD and cardiovascular disease (CVD) [1]. …

Halbesma N, Kuiken DS, Gansevoort RT, et al. Macroalbuminuria is a better risk marker than low estimated GFR to identify individuals at risk for accelerated GFR loss in population screening. J Am Soc Nephrol. 2006;17(9):2582–90.CrossRefPubMed

Motoyoshi Y, Matsusaka T, Ichikawa I, et al. Megalin contributes to the early injury of proximal tubule cells during nonselective proteinuria. Kidney Int. 2008;74(10):1262–9.CrossRefPubMedPubMedCentral

Zhang Z, Shahinfar S, Snapinn SM, et al. Importance of baseline distribution of proteinuria in renal outcomes trials: lessons from the reduction of endpoints in NIDDM with the angiotensin II antagonist losartan (RENAAL) study. J Am Soc Nephrol. 2005;16(6):1775–80.CrossRefPubMed

Iseki K, Ikemiya Y, Takishita S, et al. Proteinuria and the risk of developing end-stage renal disease. Kidney Int. 2003;63(4):1468–74.CrossRefPubMed

Gerstein HC, Mann JF, Yusuf S, et al. Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA. 2001;286(4):421–6.CrossRefPubMed

Arnlöv J, Evans JC, Vasan RS, et al. Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: the Framingham Heart Study. Circulation. 2005;112(7):969–75.CrossRefPubMed

Zandbergen AA, Vogt L, Bootsma AH, et al. Change in albuminuria is predictive of cardiovascular outcome in normotensive patients with type 2 diabetes and microalbuminuria. Diabetes Care. 2007;30(12):3119–21.CrossRefPubMed

Gaspari F, Perico N, Remuzzi G. Timed urine collections are not needed to measure urine protein excretion in clinical practice. Am J Kidney Dis. 2006;47(1):1–7.CrossRefPubMed

Ruggenenti P, Gaspari F, Remuzzi G, et al. Cross sectional longitudinal study of spot morning urine protein:creatinine ratio, 24 hour urine protein excretion rate, glomerular filtration rate, and end stage renal failure in chronic renal disease in patients without diabetes. BMJ. 1998;316(7130):504–9.CrossRefPubMedPubMedCentral

10.

Piller LB, Ford CE, Probstfield JL, et al. Incidence and predictors of angioedema in elderly hypertensive patients at high risk for cardiovascular disease: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). J Clin Hypertens (Greenwich). 2006;8(9):649–56.CrossRef

11.

Forbes GB, Bruining GJ. Urinary creatinine excretion and lean body mass. Am J Clin Nutr. 1976;29(12):1359–66.PubMed

12.

Baxmann AC, Ahmed MS, Heilberg IP, et al. Influence of muscle mass and physical activity on serum and urinary creatinine and serum cystatin C. Clin J Am Soc Nephrol. 2008;3(2):348–54.CrossRefPubMedPubMedCentral

13.

Moon SJ, Kim TH, Hwang HJ, et al. Relationship between stage of chronic kidney disease and sarcopenia in Korean Aged 40 years and older using the Korea National Health and Nutrition Examination Surveys (KNHANES IV-2, 3, and V-1, 2), 2008–2011. PLoS ONE. 2015;10(6):e0130740.CrossRefPubMedPubMedCentral

14.

Tanaka T, Okamura T, Hashimoto T, et al. A simple method to estimate populational 24-h urinary sodium and potassium excretion using a casual urine specimen. J Hum Hypertens. 2002;16(2):97–103.CrossRefPubMed

15.

Ubukata M, Takei T, Nitta K. Estimation of the 24-h urinary protein excretion based on the estimated urinary creatinine output. Clin Exp Nephrol. 2015. doi:10.1007/s10157-015-1178-z PubMed

16.

Chen CF, Yang WC, Lin CC, et al. Urinary protein/creatinine ratio weighted by estimated urinary creatinine improves the accuracy of predicting daily proteinuria. Am J Med Sci. 2015;349(6):477–87.CrossRefPubMed

Titel: Accurate estimation of protein/creatinine ratio on urine sample in CKD patients
verfasst von: Kensei Taguchi
Seiji Ueda
Kei Fukami
Publikationsdatum: 05.02.2016
Verlag: Springer Japan
Erschienen in: Clinical and Experimental Nephrology / Ausgabe 3/2016
Print ISSN: 1342-1751
Elektronische ISSN: 1437-7799
DOI: https://doi.org/10.1007/s10157-016-1229-0

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