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Journal of Thrombosis and Thrombolysis
Erschienen in: Journal of Thrombosis and Thrombolysis 1/2019

19.04.2019

Acquired Von Willebrand Syndrome (AVWS) in cardiovascular disease: a state of the art review for clinicians

verfasst von: Radha Mehta, Muhammad Athar, Sameh Girgis, Atif Hassan, Richard C. Becker

Erschienen in: Journal of Thrombosis and Thrombolysis | Ausgabe 1/2019

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Abstract

Von Willebrand Factor (vWF) is a large glycoprotein with a broad range of physiological and pathological functions in health and disease. While vWF is critical for normal hemostasis, vascular integrity and repair, quantitative and qualitative abnormalities in the molecule can predispose to serious bleeding and thrombosis. The heritable form of von Willebrand Disease was first described nearly a century ago, but more recently, recognition of an acquired condition known as acquired von Willebrand Syndrome (AVWF) has emerged in persons with hematological, endocrine and cardiovascular diseases, disorders and conditions. An in-depth understanding of the causes, diagnostic approach and management of AVWS is important for practicing clinicians.
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Metadaten
Titel
Acquired Von Willebrand Syndrome (AVWS) in cardiovascular disease: a state of the art review for clinicians
verfasst von
Radha Mehta
Muhammad Athar
Sameh Girgis
Atif Hassan
Richard C. Becker
Publikationsdatum
19.04.2019
Verlag
Springer US
Erschienen in
Journal of Thrombosis and Thrombolysis / Ausgabe 1/2019
Print ISSN: 0929-5305
Elektronische ISSN: 1573-742X
DOI
https://doi.org/10.1007/s11239-019-01849-2

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