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Acta Neuropathologica

Ausgabe 1/2012

Inhalt (12 Artikel)

Consensus Paper

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

Thomas J. Montine, Creighton H. Phelps, Thomas G. Beach, Eileen H. Bigio, Nigel J. Cairns, Dennis W. Dickson, Charles Duyckaerts, Matthew P. Frosch, Eliezer Masliah, Suzanne S. Mirra, Peter T. Nelson, Julie A. Schneider, Dietmar Rudolf Thal, John Q. Trojanowski, Harry V. Vinters, Bradley T. Hyman

Review

Mild cognitive impairment: pathology and mechanisms

Elliott J. Mufson, Lester Binder, Scott E. Counts, Steven T. DeKosky, Leyla deToledo-Morrell, Stephen D. Ginsberg, Milos D. Ikonomovic, Sylvia E. Perez, Stephen W. Scheff

Original Paper

The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain

Tsuyoshi Hamaguchi, Yvonne S. Eisele, Nicholas H. Varvel, Bruce T. Lamb, Lary C. Walker, Mathias Jucker

Original Paper

Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer’s disease and apoE TR mouse cortex

Stephen Arold, Patrick Sullivan, Tina Bilousova, Edmond Teng, Carol A. Miller, Wayne W. Poon, Harry V. Vinters, Lindsey B. Cornwell, Tommy Saing, Gregory M. Cole, Karen Hoppens Gylys

Open Access Original Paper

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

Raquel Sanchez-Varo, Laura Trujillo-Estrada, Elisabeth Sanchez-Mejias, Manuel Torres, David Baglietto-Vargas, Ines Moreno-Gonzalez, Vanessa De Castro, Sebastian Jimenez, Diego Ruano, Marisa Vizuete, Jose Carlos Davila, Jose Manuel Garcia-Verdugo, Antonio Jesus Jimenez, Javier Vitorica, Antonia Gutierrez

Original Paper

Entorhinal verrucae geometry is coincident and correlates with Alzheimer’s lesions: a combined neuropathology and high-resolution ex vivo MRI analysis

Jean C. Augustinack, Kristen E. Huber, Gheorghe M. Postelnicu, Sita Kakunoori, Ruopeng Wang, André J. W. van der Kouwe, Lawrence L. Wald, Thor D. Stein, Matthew P. Frosch, Bruce Fischl

Open Access Original Paper

Hyperphosphorylated tau in young and middle-aged subjects

Adila Elobeid, Hilkka Soininen, Irina Alafuzoff

Open Access Original Paper

Dual modification of Alzheimer’s disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach

Stefani N. Thomas, Kristen E. Funk, Yunhu Wan, Zhongping Liao, Peter Davies, Jeff Kuret, Austin J. Yang

Original Paper

Selective tau tyrosine nitration in non-AD tauopathies

Juan F. Reyes, Changiz Geula, Laurel Vana, Lester I. Binder

Original Paper

An experimental rat model of sporadic Alzheimer’s disease and rescue of cognitive impairment with a neurotrophic peptide

Silvia Bolognin, Julie Blanchard, Xiaochuan Wang, Gustavo Basurto-Islas, Yunn Chyn Tung, Erik Kohlbrenner, Inge Grundke-Iqbal, Khalid Iqbal

Correspondence

Neuropathological subtypes of Alzheimer’s disease

Kurt A. Jellinger

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