Ausgabe 4/2014
Inhalt (14 Artikel)
Is there a risk of prion-like disease transmission by Alzheimer- or Parkinson-associated protein particles?
Michael Beekes, Achim Thomzig, Walter J. Schulz-Schaeffer, Reinhard Burger
Aβ seeds resist inactivation by formaldehyde
Sarah K. Fritschi, Amarallys Cintron, Lan Ye, Jasmin Mahler, Anika Bühler, Frank Baumann, Manuela Neumann, K. Peter R. Nilsson, Per Hammarström, Lary C. Walker, Mathias Jucker
C9orf72 FTLD/ALS-associated Gly-Ala dipeptide repeat proteins cause neuronal toxicity and Unc119 sequestration
Stephanie May, Daniel Hornburg, Martin H. Schludi, Thomas Arzberger, Kristin Rentzsch, Benjamin M. Schwenk, Friedrich A. Grässer, Kohji Mori, Elisabeth Kremmer, Julia Banzhaf-Strathmann, Matthias Mann, Felix Meissner, Dieter Edbauer
Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress
Yong-Jie Zhang, Karen Jansen-West, Ya-Fei Xu, Tania F. Gendron, Kevin F. Bieniek, Wen-Lang Lin, Hiroki Sasaguri, Thomas Caulfield, Jaime Hubbard, Lillian Daughrity, Jeannie Chew, Veronique V. Belzil, Mercedes Prudencio, Jeannette N. Stankowski, Monica Castanedes-Casey, Ena Whitelaw, Peter E. A. Ash, Michael DeTure, Rosa Rademakers, Kevin B. Boylan, Dennis W. Dickson, Leonard Petrucelli
C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD
Elaine Y. Liu, Jenny Russ, Kathryn Wu, Donald Neal, Eunran Suh, Anna G. McNally, David J. Irwin, Vivianna M. Van Deerlin, Edward B. Lee
A comparison of Aβ amyloid pathology staging systems and correlation with clinical diagnosis
Susana Boluda, Jon B. Toledo, David J. Irwin, Kevin M. Raible, Matt D. Byrne, Edward B. Lee, Virginia M.-Y. Lee, John Q. Trojanowski
Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma
Felix Sahm, David Reuss, Christian Koelsche, David Capper, Jens Schittenhelm, Stephanie Heim, David T. W. Jones, Stefan M. Pfister, Christel Herold-Mende, Wolfgang Wick, Wolf Mueller, Christian Hartmann, Werner Paulus, Andreas von Deimling
Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma
Benedikt Wiestler, David Capper, Martin Sill, David T. W. Jones, Volker Hovestadt, Dominik Sturm, Christian Koelsche, Anna Bertoni, Leonille Schweizer, Andrey Korshunov, Elisa K. Weiß, Maximilian G. Schliesser, Alexander Radbruch, Christel Herold-Mende, Patrick Roth, Andreas Unterberg, Christian Hartmann, Torsten Pietsch, Guido Reifenberger, Peter Lichter, Bernhard Radlwimmer, Michael Platten, Stefan M. Pfister, Andreas von Deimling, Michael Weller, Wolfgang Wick
Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications
Pawel Buczkowicz, Ute Bartels, Eric Bouffet, Oren Becher, Cynthia Hawkins
Germ-line and somatic DICER1 mutations in pineoblastoma
Leanne de Kock, Nelly Sabbaghian, Harriet Druker, Evan Weber, Nancy Hamel, Suzanne Miller, Catherine S. Choong, Nicholas G. Gottardo, Ursula R. Kees, Surya P. Rednam, Liselotte P. van Hest, Marjolijn C. Jongmans, Shalini Jhangiani, James R. Lupski, Margaret Zacharin, Dorothée Bouron-Dal Soglio, Annie Huang, John R. Priest, Arie Perry, Sabine Mueller, Steffen Albrecht, David Malkin, Richard G. Grundy, William D. Foulkes
FTLD-ALS of TDP-43 type and SCA2 in a family with a full ataxin-2 polyglutamine expansion
Dirk Bäumer, Simon Z. East, Bing Tseu, Adam Zeman, David Hilton, Kevin Talbot, Olaf Ansorge
Subventricular spread of diffuse intrinsic pontine glioma
Viola Caretti, Marianna Bugiani, Morgan Freret, Pepijn Schellen, Marc Jansen, Dannis van Vuurden, Gertjan Kaspers, Paul G. Fisher, Esther Hulleman, Pieter Wesseling, Hannes Vogel, Michelle Monje
Anti-Aβ antibody target engagement: commentary regarding Watt et al. Acta Neuropathol 127:803–810 (2014)
Eric Siemers, Robert A. Dean, Ronald B. DeMattos, Michael L. Hutton, Kaj Blennow, Leslie M. Shaw, David M. Holtzman
Anti-Aβ antibody target engagement: a response to Siemers et al.
Andrew D. Watt, Gabriela A. N. Crespi, Russell A. Down, David B. Ascher, Adam Gunn, Keyla A. Perez, Catriona A. McLean, Victor L. Villemagne, Michael W. Parker, Kevin J. Barnham, Luke A. Miles