Ausgabe 4/2015
Inhalt (13 Artikel)
Inflammatory neuropathies: pathology, molecular markers and targets for specific therapeutic intervention
Eroboghene E. Ubogu
Astrocyte pathology in Alexander disease causes a marked inflammatory environment
Markel Olabarria, Maria Putilina, Ellen C. Riemer, James E. Goldman
Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer’s disease
Yang Xiang, Xian-Le Bu, Yu-Hui Liu, Chi Zhu, Lin-Lin Shen, Shu-Sheng Jiao, Xiao-Yan Zhu, Brian Giunta, Jun Tan, Wei-Hong Song, Hua-Dong Zhou, Xin-Fu Zhou, Yan-Jiang Wang
Regional mosaic genomic heterogeneity in the elderly and in Alzheimer’s disease as a correlate of neuronal vulnerability
Thomas Arendt, Martina K. Brückner, Andreas Lösche
Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology
Emma L. Clayton, Sarah Mizielinska, James R. Edgar, Troels Tolstrup Nielsen, Sarah Marshall, Frances E. Norona, Miranda Robbins, Hana Damirji, Ida E. Holm, Peter Johannsen, Jørgen E. Nielsen, Emmanuel A. Asante, John Collinge, Adrian M. Isaacs
FTD/ALS-associated poly(GR) protein impairs the Notch pathway and is recruited by poly(GA) into cytoplasmic inclusions
Dejun Yang, Abbas Abdallah, Zhaodong Li, Yubing Lu, Sandra Almeida, Fen-Biao Gao
Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
Martin H. Schludi, Stephanie May, Friedrich A. Grässer, Kristin Rentzsch, Elisabeth Kremmer, Clemens Küpper, Thomas Klopstock, Thomas Arzberger, Dieter Edbauer
Erratum to: Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
Martin H. Schludi, Stephanie May, Friedrich A. Grässer, Kristin Rentzsch, Elisabeth Kremmer, Clemens Küpper, Thomas Klopstock, Thomas Arzberger, Dieter Edbauer
Cerebellar c9RAN proteins associate with clinical and neuropathological characteristics of C9ORF72 repeat expansion carriers
Tania F. Gendron, Marka van Blitterswijk, Kevin F. Bieniek, Lillian M. Daughrity, Jie Jiang, Beth K. Rush, Otto Pedraza, John A. Lucas, Melissa E. Murray, Pamela Desaro, Amelia Robertson, Karen Overstreet, Colleen S. Thomas, Julia E. Crook, Monica Castanedes-Casey, Linda Rousseau, Keith A. Josephs, Joseph E. Parisi, David S. Knopman, Ronald C. Petersen, Bradley F. Boeve, Neill R. Graff-Radford, Rosa Rademakers, Clotilde Lagier-Tourenne, Dieter Edbauer, Don W. Cleveland, Dennis W. Dickson, Leonard Petrucelli, Kevin B. Boylan
A clinicopathologic study of diencephalic pediatric low-grade gliomas with BRAF V600 mutation
Cheng-Ying Ho, Bret C. Mobley, Heather Gordish-Dressman, Christopher J. VandenBussche, Gary E. Mason, Miriam Bornhorst, Adam J. Esbenshade, Mahtab Tehrani, Brent A. Orr, Delecia R. LaFrance, Joseph M. Devaney, Beatrix W. Meltzer, Sean E. Hofherr, Peter C. Burger, Roger J. Packer, Fausto J. Rodriguez
Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma
Qun Liu, Yuexin Liu, Wenliang Li, Xiaoguang Wang, Raymond Sawaya, Frederick F. Lang, W. K. Alfred Yung, Kexin Chen, Gregory N. Fuller, Wei Zhang
A 30-unit hexanucleotide repeat expansion in C9orf72 induces pathological lesions with dipeptide-repeat proteins and RNA foci, but not TDP-43 inclusions and clinical disease
Priya Gami, Christina Murray, Lucia Schottlaender, Conceição Bettencourt, Eduardo De Pablo Fernandez, Ese Mudanohwo, Sarah Mizielinska, James M. Polke, Janice L. Holton, Adrian M. Isaacs, Henry Houlden, Tamas Revesz, Tammaryn Lashley
Erratum to: Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain
Raluca Reitmeir, Ertugrul Kilic, Barbara S. Reinboth, Zeyun Guo, Ayman ElAli, Anil Zechariah, Ülkan Kilic, Dirk M. Hermann