Acta Neuropathologica

CSF Apo-E levels associate with cognitive decline and MRI changes

Jon B. Toledo, Xiao Da, Michael W. Weiner, David A. Wolk, Sharon X. Xie, Steven E. Arnold, Christos Davatzikos, Leslie M. Shaw, John Q. Trojanowski

Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer’s disease patients and controls

Eduardo Martínez-Morillo, Oskar Hansson, Yuka Atagi, Guojun Bu, Lennart Minthon, Eleftherios P. Diamandis, Henrietta M. Nielsen

Amyloidogenic α-synuclein seeds do not invariably induce rapid, widespread pathology in mice

Amanda N. Sacino, Mieu Brooks, Michael A. Thomas, Alex B. McKinney, Nicholas H. McGarvey, Nicola J. Rutherford, Carolina Ceballos-Diaz, Janice Robertson, Todd E. Golde, Benoit I. Giasson

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

Zeshan Ahmed, Jane Cooper, Tracey K. Murray, Katya Garn, Emily McNaughton, Hannah Clarke, Samira Parhizkar, Mark A. Ward, Annalisa Cavallini, Samuel Jackson, Suchira Bose, Florence Clavaguera, Markus Tolnay, Isabelle Lavenir, Michel Goedert, Michael L. Hutton, Michael J. O’Neill

Neurofibrillary tangle formation by introducing wild-type human tau into APP transgenic mice

Tomohiro Umeda, Satomi Maekawa, Tetsuya Kimura, Akihiko Takashima, Takami Tomiyama, Hiroshi Mori

P-glycoprotein regulates trafficking of CD8+ T cells to the brain parenchyma

Gijs Kooij, Jeffrey Kroon, Debayon Paul, Arie Reijerkerk, Dirk Geerts, Susanne M. A. van der Pol, Bert van het Hof, Joost A. Drexhage, Sandra J. van Vliet, Liesbeth H. P. Hekking, Jaap D. van Buul, Joel S. Pachter, Helga E. de Vries

Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses

Nils Schweingruber, Henrike J. Fischer, Lisa Fischer, Jens van den Brandt, Anna Karabinskaya, Verena Labi, Andreas Villunger, Benedikt Kretzschmar, Peter Huppke, Mikael Simons, Jan P. Tuckermann, Alexander Flügel, Fred Lühder, Holger M. Reichardt

Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma

Lindsey M. Hoffman, Andrew M. Donson, Ichiro Nakachi, Andrea M. Griesinger, Diane K. Birks, Vladimir Amani, Molly S. Hemenway, Arthur K. Liu, Michael Wang, Todd C. Hankinson, Michael H. Handler, Nicholas K. Foreman

Quantitative assessment of intragenic receptor tyrosine kinase deletions in primary glioblastomas: their prevalence and molecular correlates

Edward R. Kastenhuber, Jason T. Huse, Samuel H. Berman, Alicia Pedraza, Jianan Zhang, Yoshiyuki Suehara, Agnes Viale, Magali Cavatore, Adriana Heguy, Nicholas Szerlip, Marc Ladanyi, Cameron W. Brennan

Myopathy in Marinesco–Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology

Andreas Roos, Stephan Buchkremer, Laxmikanth Kollipara, Thomas Labisch, Christian Gatz, Manuela Zitzelsberger, Eva Brauers, Kay Nolte, J. Michael Schröder, Janbernd Kirschner, Christopher Marvin Jesse, Hans Hilmar Goebel, Anand Goswami, Richard Zimmermann, René Peiman Zahedi, Jan Senderek, Joachim Weis

The oligomer modulator anle138b inhibits disease progression in a Parkinson mouse model even with treatment started after disease onset

Johannes Levin, Felix Schmidt, Cathrin Boehm, Catharina Prix, Kai Bötzel, Sergey Ryazanov, Andrei Leonov, Christian Griesinger, Armin Giese

Acknowledgement to referees