Ausgabe 5/2015
Inhalt (13 Artikel)
Amyloid deposits and inflammatory infiltrates in sporadic inclusion body myositis: the inflammatory egg comes before the degenerative chicken
Olivier Benveniste, Werner Stenzel, David Hilton-Jones, Marco Sandri, Olivier Boyer, Baziel G. M. van Engelen
Soluble VCAM-1 impairs human brain endothelial barrier integrity via integrin α-4-transduced outside-in signalling
Axel Haarmann, Eva Nowak, Annika Deiß, Susanne van der Pol, Camelia-Maria Monoranu, Gijs Kooij, Nora Müller, Paul van der Valk, Guido Stoll, Helga E. de Vries, Friederike Berberich-Siebelt, Mathias Buttmann
M. leprae components induce nerve damage by complement activation: identification of lipoarabinomannan as the dominant complement activator
Nawal Bahia El Idrissi, Pranab K. Das, Kees Fluiter, Patricia S. Rosa, Jeroen Vreijling, Dirk Troost, B. Paul Morgan, Frank Baas, Valeria Ramaglia
Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
Andrey Korshunov, Marina Ryzhova, Volker Hovestadt, Sebastian Bender, Dominik Sturm, David Capper, Jochen Meyer, Daniel Schrimpf, Marcel Kool, Paul A. Northcott, Olga Zheludkova, Till Milde, Olaf Witt, Andreas E. Kulozik, Guido Reifenberger, Nada Jabado, Arie Perry, Peter Lichter, Andreas von Deimling, Stefan M. Pfister, David T. W. Jones
Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups
Michael Weller, Ruthild G. Weber, Edith Willscher, Vera Riehmer, Bettina Hentschel, Markus Kreuz, Jörg Felsberg, Ulrike Beyer, Henry Löffler-Wirth, Kerstin Kaulich, Joachim P. Steinbach, Christian Hartmann, Dorothee Gramatzki, Johannes Schramm, Manfred Westphal, Gabriele Schackert, Matthias Simon, Tobias Martens, Jan Boström, Christian Hagel, Michael Sabel, Dietmar Krex, Jörg C. Tonn, Wolfgang Wick, Susan Noell, Uwe Schlegel, Bernhard Radlwimmer, Torsten Pietsch, Markus Loeffler, Andreas von Deimling, Hans Binder, Guido Reifenberger
Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation
Marcel Kunadt, Katrin Eckermann, Anne Stuendl, Jing Gong, Belisa Russo, Katrin Strauss, Surya Rai, Sebastian Kügler, Lisandro Falomir Lockhart, Martin Schwalbe, Petranka Krumova, Luis M. A. Oliveira, Mathias Bähr, Wiebke Möbius, Johannes Levin, Armin Giese, Niels Kruse, Brit Mollenhauer, Ruth Geiss-Friedlander, Albert C. Ludolph, Axel Freischmidt, Marisa S. Feiler, Karin M. Danzer, Markus Zweckstetter, Thomas M. Jovin, Mikael Simons, Jochen H. Weishaupt, Anja Schneider
The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients
Zhengrui Xi, Ming Zhang, Amalia C. Bruni, Raffaele G. Maletta, Rosanna Colao, Pietro Fratta, James M. Polke, Mary G. Sweeney, Ese Mudanohwo, Benedetta Nacmias, Sandro Sorbi, Maria Carmela Tartaglia, Innocenzo Rainero, Elisa Rubino, Lorenzo Pinessi, Daniela Galimberti, Ezequiel I. Surace, Philip McGoldrick, Paul McKeever, Danielle Moreno, Christine Sato, Yan Liang, Julia Keith, Lorne Zinman, Janice Robertson, Ekaterina Rogaeva
Neuropathologically mixed Alzheimer’s and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes
Lauren Walker, Kirsty E. McAleese, Alan J. Thomas, Mary Johnson, Carmen Martin-Ruiz, Craig Parker, Sean J. Colloby, Kurt Jellinger, Johannes Attems
PART is part of Alzheimer disease
Charles Duyckaerts, Heiko Braak, Jean-Pierre Brion, Luc Buée, Kelly Del Tredici, Michel Goedert, Glenda Halliday, Manuela Neumann, Maria Grazia Spillantini, Markus Tolnay, Toshiki Uchihara
PART, a distinct tauopathy, different from classical sporadic Alzheimer disease
Kurt A. Jellinger, Irina Alafuzoff, Johannes Attems, Thomas G. Beach, Nigel J. Cairns, John F. Crary, Dennis W. Dickson, Patrick R. Hof, Bradley T. Hyman, Clifford R. Jack Jr., Gregory A. Jicha, David S. Knopman, Gabor G. Kovacs, Ian R. Mackenzie, Eliezer Masliah, Thomas J. Montine, Peter T. Nelson, Frederick Schmitt, Julie A. Schneider, Albert Serrano-Pozo, Dietmar R. Thal, Jonathan B. Toledo, John Q. Trojanowski, Juan C. Troncoso, Jean Paul Vonsattel, Thomas Wisniewski
Does the difference between PART and Alzheimer’s disease lie in the age-related changes in cerebral arteries that trigger the accumulation of Aβ and propagation of tau?
Roy O. Weller, Cheryl A. Hawkes, Roxana O. Carare, John Hardy