Ausgabe 5/2021
Inhalt (15 Artikel)
The mechanistic link between selective vulnerability of the locus coeruleus and neurodegeneration in Alzheimer’s disease
Billie J. Matchett, Lea T. Grinberg, Panos Theofilas, Melissa E. Murray
Patterns of neuronal Rhes as a novel hallmark of tauopathies
Alexander J. Ehrenberg, Kun Leng, Kaitlyn N. Letourneau, Israel Hernandez, Caroline Lew, William W. Seeley, Salvatore Spina, Bruce Miller, Helmut Heinsen, Martin Kampmann, Kenneth S. Kosik, Lea T. Grinberg
Latent trait modeling of tau neuropathology in progressive supranuclear palsy
Naomi Kouri, Melissa E. Murray, Joseph S. Reddy, Daniel J. Serie, Alexandra Soto-Beasley, Mariet Allen, Minerva M. Carrasquillo, Xue Wang, Monica Casey Castanedes, Matthew C. Baker, Rosa Rademakers, Ryan J. Uitti, Neill R. Graff-Radford, Zbigniew K. Wszolek, Gerard D. Schellenberg, Julia E. Crook, Nilüfer Ertekin-Taner, Owen A. Ross, Dennis W. Dickson
Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease
Emma Gerrits, Nieske Brouwer, Susanne M. Kooistra, Maya E. Woodbury, Yannick Vermeiren, Mirjam Lambourne, Jan Mulder, Markus Kummer, Thomas Möller, Knut Biber, Wilfred F. A. den Dunnen, Peter P. De Deyn, Bart J. L. Eggen, Erik W. G. M. Boddeke
Cryo-EM structures of tau filaments from Alzheimer’s disease with PET ligand APN-1607
Yang Shi, Alexey G. Murzin, Benjamin Falcon, Alexander Epstein, Jonathan Machin, Paul Tempest, Kathy L. Newell, Ruben Vidal, Holly J. Garringer, Naruhiko Sahara, Makoto Higuchi, Bernardino Ghetti, Ming-Kuei Jang, Sjors H. W. Scheres, Michel Goedert
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology
Nicholas J. Ashton, Tharick A. Pascoal, Thomas K. Karikari, Andréa L. Benedet, Juan Lantero-Rodriguez, Gunnar Brinkmalm, Anniina Snellman, Michael Schöll, Claire Troakes, Abdul Hye, Serge Gauthier, Eugeen Vanmechelen, Henrik Zetterberg, Pedro Rosa-Neto, Kaj Blennow
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites
Jacqueline M. Tokarew, Daniel N. El-Kodsi, Nathalie A. Lengacher, Travis K. Fehr, Angela P. Nguyen, Bojan Shutinoski, Brian O’Nuallain, Ming Jin, Jasmine M. Khan, Andy C. H. Ng, Juan Li, Qiubo Jiang, Mei Zhang, Liqun Wang, Rajib Sengupta, Kathryn R. Barber, An Tran, Doo Soon Im, Steve Callaghan, David S. Park, Stephanie Zandee, Xiajun Dong, Clemens R. Scherzer, Alexandre Prat, Eve C. Tsai, Masashi Takanashi, Nobutaka Hattori, Jennifer A. Chan, Luigi Zecca, Andrew B. West, Arne Holmgren, Lawrence Puente, Gary S. Shaw, Gergely Toth, John M. Woulfe, Peggy Taylor, Julianna J. Tomlinson, Michael G. Schlossmacher
Proteomic identification of select protein variants of the SNARE interactome associated with cognitive reserve in a large community sample
Alfredo Ramos-Miguel, Andrea A. Jones, Vladislav A. Petyuk, Vilte E. Barakauskas, Alasdair M. Barr, Sue E. Leurgans, Philip L. De Jager, Kaitlin B. Casaletto, Julie A. Schneider, David A. Bennett, William G. Honer
Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study
Anthony P. Y. Liu, Bryan K. Li, Elke Pfaff, Brian Gudenas, Alexandre Vasiljevic, Brent A. Orr, Christelle Dufour, Matija Snuderl, Matthias A. Karajannis, Marc K. Rosenblum, Eugene I. Hwang, Ho-Keung Ng, Jordan R. Hansford, Alexandru Szathmari, Cécile Faure-Conter, Thomas E. Merchant, Max Levine, Nancy Bouvier, Katja von Hoff, Martin Mynarek, Stefan Rutkowski, Felix Sahm, Marcel Kool, Cynthia Hawkins, Arzu Onar-Thomas, Giles W. Robinson, Amar Gajjar, Stefan M. Pfister, Eric Bouffet, Paul A. Northcott, David T. W. Jones, Annie Huang
Validation of the new pathology staging system for progressive supranuclear palsy
Mayen Briggs, Kieren Simon James Allinson, Maura Malpetti, Maria Grazia Spillantini, James Benedict Rowe, Sanne Simone Kaalund
Globular glial tauopathy with a mutation in MAPT and unusual TDP-43 proteinopathy in a patient with behavioural-variant frontotemporal dementia
Shelley L. Forrest, Claire E. Shepherd, Heather McCann, John B. Kwok, Glenda M. Halliday, Jillian J. Kril
TDP-43 interacts with pathological τ protein in Alzheimer’s disease
Sandra O. Tomé, Luis A. Gomes, Xiaohang Li, Rik Vandenberghe, Thomas Tousseyn, Dietmar Rudolf Thal
Antibodies to MOG in CSF only: pathological findings support the diagnostic value
Sara Carta, Romana Höftberger, Anna Bolzan, Silvia Bozzetti, Bruno Bonetti, Mauro Scarpelli, Sarah Ottaviani, Claudio Ghimenton, Daniela Alberti, Kathrin Schanda, Markus Reindl, Romain Marignier, Sergio Ferrari, Sara Mariotto
ATP10B variants in Parkinson’s disease: a large cohort study in Chinese mainland population
Yuwen Zhao, Hongxu Pan, Yige Wang, Qian Zeng, Zhenghuan Fang, Runcheng He, Kun Xu, Xiaoxia Zhou, Xun Zhou, Zhou Zhou, Yanghong Li, Penghui Deng, Yinghui Xu, Qian Xu, Qiying Sun, Bin Li, Guihu Zhao, Lifang Lei, Hainan Zhang, Chunyu Wang, Jieqiong Tan, Xinxiang Yan, Lu Shen, Hong Jiang, Jinchen Li, Jifeng Guo, Beisha Tang, Zhenhua Liu
Reply: ATP10B variants in Parkinson’s disease—a large cohort study in Chinese mainland population
Stefanie Smolders, Christine Van Broeckhoven