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08.11.2018 | Case Report

Actinomyces spp. bloodstream and deep vein thrombus infections in people who inject drugs

verfasst von: Emma Tippett, Nupur Goyal, Stephen Guy, Jenny Wong

Erschienen in: Infection | Ausgabe 3/2019

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Abstract

Introduction

Actinomyces spp. cause several well-described syndromes including cervicofacial and pelvic infections. Actinomyces spp. infection as an opportunistic infection among people who inject drugs has rarely been described with few case reports published.

Methods and results

Here we describe four people who inject drugs admitted with Actinomyces spp. infections, all with an overlapping syndrome and who presented a challenge to both diagnose and to manage.

Discussion

This case series highlights the potential to overlook Actinomyces spp. infection in people who inject drugs and aims to increase clinician awareness of diagnosis, empirical and directed treatment, and potential complications of this infection.

Wong VK, Turmezei TD, Weston VC. Actinomycosis. BMJ. 2011;343:d6099.CrossRefPubMed

Holm P. Studies on the aetiology of human actinomycosis. Acta Pathol Microbiol Scand Suppl. 1951;91:172–3.PubMed

Bonnefond S, Catroux M, Melenotte C, Karkowski L, Rolland L, Trouillier S, et al. Clinical features of actinomycosis: a retrospective, multicenter study of 28 cases of miscellaneous presentations. Medicine (Baltimore). 2016;95(24):e3923.CrossRef

Bing AU, Loh SF, Morris T, Hughes H, Dixon JM, Helgason KO. Actinomyces species isolated from breast infections. J Clin Microbiol. 2015;53 10:3247–55.CrossRef

Summanen PH, Talan DA, Strong C, McTeague M, Bennion R, Thompson JE Jr, et al. Bacteriology of skin and soft-tissue infections: comparison of infections in intravenous drug users and individuals with no history of intravenous drug use. Clin Infect Dis. 1995;20(Suppl 2):279–82.

Weiand D, Barlow G. The rising tide of bloodstream infections with Actinomyces species: bimicrobial infection with Actinomyces odontolyticus and Escherichia coli in an intravenous drug user. Oxf Med Case Rep. 2014;2014 9:156–8.CrossRef

Hoye S, Tolan D, Brownjohn A. Septic pulmonary embolism in an intravenous drug user. Acute Med. 2010;9(1):15–9.PubMed

Mehrzad R, Sublette M, Barza M. Polymicrobial endocarditis in intravenous heroin and fentanyl abuse. J Clin Diagn Res. 2013;7 12:2981–5.

Oh S, Havlen PR, Hussain N. A case of polymicrobial endocarditis due to anaerobic organisms in an injection drug user. J Gen Intern Med. 2005;20 10:958-.CrossRef

10.

Westling K, Lidman C, Thalme A. Tricuspid valve endocarditis caused by a new species of actinomyces: Actinomyces funkei. Scand J Infect Dis. 2002;34(3):206–7.CrossRefPubMed

11.

Sofianou D, Avgoustinakis E, Dilopoulou A, Pournaras S, Tsirakidis G, Tsakris A. Soft-tissue abscess involving Actinomyces odontolyticus and two Prevotella species in an intravenous drug abuser. Comp Immunol Microbiol Infect Dis. 2004;27(2):75–9.CrossRefPubMed

12.

Webb D, Thadepalli H. Skin and soft tissue polymicrobial infections from intravenous abuse of drugs. West J Med. 1979;130 3:200–4.

13.

Zaman R, Abbas M, Burd E. Late prosthetic hip joint infection with Actinomyces israelii in an intravenous drug user: case report and literature review. J Clin Microbiol. 2002;40 11:4391–2.CrossRef

14.

Bennhoff DF. Actinomycosis: diagnostic and therapeutic considerations and a review of 32 cases. Laryngoscope. 1984;94(9):1198–217.CrossRefPubMed

15.

Clarridge JE III, Zhang Q. Genotypic diversity of clinical Actinomyces species: phenotype, source, and disease correlation among genospecies. J Clin Microbiol. 2002;40(9):3442–8.CrossRefPubMed

16.

Lerner PI. The lumpy jaw. Cervicofacial actinomycosis. Infect Dis Clin North Am. 1988;2(1):203–20.PubMed

17.

Smith AJ, Hall V, Thakker B, Gemmell CG. Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents. J Antimicrob Chemother. 2005;56(2):407–9.CrossRefPubMed

18.

Macfarlane DJ, Tucker LG, Kemp RJ. Treatment of recalcitrant actinomycosis with ciprofloxacin. J Infect. 1993;27(2):177–80.CrossRefPubMed

19.

Prashant N, Azuhairy A. Actinomycosis of distal phalanx twenty years after flap reconstruction of index finger: a case report. Malays Orthop J. 2018;12(1):48–50.CrossRefPubMedPubMedCentral

20.

Atad J, Hallak M, Sharon A, Kitzes R, Kelner Y, Abramovici H. Pelvic actinomycosis. Is long-term antibiotic therapy necessary? J Reprod Med. 1999;44(11):939–44.PubMed

Titel: Actinomyces spp. bloodstream and deep vein thrombus infections in people who inject drugs
verfasst von: Emma Tippett
Nupur Goyal
Stephen Guy
Jenny Wong
Publikationsdatum: 08.11.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: Infection / Ausgabe 3/2019
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-018-1246-x

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Actinomyces spp. bloodstream and deep vein thrombus infections in people who inject drugs

Abstract

Introduction

Methods and results

Discussion

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Abstract

Introduction

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Discussion

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