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01.12.2017 | Case report | Ausgabe 1/2017 Open Access

Journal of Medical Case Reports 1/2017

Acute corneal hydrops during pregnancy with spontaneous resolution after corneal cross-linking for keratoconus: a case report

Journal of Medical Case Reports > Ausgabe 1/2017
Ricardo Alexandre Stock, Thaís Thumé, Elcio Luiz Bonamigo



Keratoconus may progress to acute corneal hydrops even after cross-linking. In some cases, keratoconus progresses during pregnancy. In this report, we present a case of a patient with increased anterior stromal resistance after cross-linking that would favor nonprogression of keratoconus during pregnancy.

Case presentation

We report that cross-linking is likely to have had a protective effect in a white pregnant patient with acute corneal hydrops who showed rapid improvement, as documented by corneal topography. Improvement occurred within 8 days, whereas up to 250 days are reported in the literature. No keratoconus progression occurred in the 20-month follow-up period.


Cross-linking failed to prevent the occurrence of acute corneal hydrops after rupture of Descemet’s membrane but most likely helped to accelerate the resolution of the condition. Corneal hardening resulting from cross-linking may have also contributed to stabilizing keratoconus during pregnancy.

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