Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Konkret geht es um den Diabetes-Patienten mit kardiovaskulären Erkrankungen oder Risiken, die Herzinsuffizienz sowie die kardiovaskuläre Primär- und Sekundärprävention. Sind Sie hier schon auf dem neuesten Stand? Unsere Experten beleuchten, wo und warum das bisherige Procedere geändert werden soll und was in der Praxis sinnvoll ist. Holen Sie sich Ihr Update und 2 CME-Punkte beim MMW-Webinar am 24. April von 17.30 bis 19 Uhr. 
Erweiterte Suche
Anmelden
nach oben
Environmental Health and Preventive Medicine
Erschienen in: Environmental Health and Preventive Medicine 5/2016

01.09.2016 | Regular Article

Acute effects on pulmonary function in young healthy adults exposed to traffic-related air pollution in semi-closed transport hub in Beijing

verfasst von: Jing Huang, Furong Deng, Shaowei Wu, Yan Zhao, Masayuki Shima, Bin Guo, Qichen Liu, Xinbiao Guo

Erschienen in: Environmental Health and Preventive Medicine | Ausgabe 5/2016

Einloggen, um Zugang zu erhalten

Abstract

Objectives

Transport hub is an important part of urban comprehensive transportation system. Traffic-related air pollution can reach high level because of difficulty of diffusion and increase of emission in transport hub. However, whether exposure in this semi-closed traffic micro-environment causes acute changes in pulmonary function of commuters still needs to be explored.

Methods

Forty young healthy adults participated in this randomized, crossover study. Each participant underwent 2 h exposure in a designated transport hub and, on a separate occasion, in an appointed park. Personal exposures to fine particulate matter (PM2.5), black carbon (BC) and carbon monoxide (CO) were measured. Forced expiratory volume in 1 s (FEV1) and peak expiratory flow (PEF) were assessed pre-, during and post-exposure. Mixed linear models were used to analyze the pulmonary effects of traffic-related air pollutants.

Results

Participants had significantly higher exposures to PM2.5, BC and CO in the transport hub than in the park. Exposure in transport hub induced significant reductions in FEV1 and PEF compared with the park during exposure 1 and 2 h. The reductions were significant associated with traffic-related air pollutants. For instance, per 10 μg/m3 increment in PM2.5 was associated with −0.15 % (95 % CI −0.28, −0.02 %) reduction in FEV1 during exposure 2 h. However, effects became attenuate after 2 h exposure.

Conclusions

Short-term exposure in transport hub had acute reduction effects on pulmonary function. More attention should be paid to the health effects of exposure in the semi-closed traffic micro-environment.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
World Health Organization. Health effects of transport-related air pollution. Copenhagen: WHO Regional Office for Europe; 2005. p. 53–67.
2.
Brunekreef B, Beelen R, Hoek G, et al. Effects of long-term exposure to traffic-related air pollution on respiratory and cardiovascular mortality in Netherlands: the NLCS-AIR study. Res Rep Health Eff Inst. 2009;139:5–71.
3.
Dong GH, Zhang P, Sun B, Zhang L, Chen X, Ma N, et al. Long-term exposure to ambient air pollution and respiratory disease mortality in Shenyang, China: a 12-year population-based retrospective cohort study. Respiration. 2012;84:360–8.CrossRefPubMed
4.
Gruzieva O, Bergström A, Hulchiy O, Kull I, Lind T, Melén E, et al. Exposure to air pollution from traffic and childhood asthma until 12 years of age. Epidemiology. 2013;24:54–61.CrossRefPubMed
5.
Nirel R, Schiff M, Paltiel O. Respiratory hospitalizations of children and residential exposure to traffic air pollution in Jerusalem. Int J Hyg Environ Heatlh. 2015;218:34–40.CrossRef
6.
Patel MM, Quinn JW, Jung KH, Hoepner L, Diaz D, Perzanowski M, et al. Traffic density and stationary sources of air pollution associated with wheeze, asthma, and immunoglobulin E from birth to age 5 years among New York City children. Environ Res. 2011;111:1222–9.CrossRefPubMedPubMedCentral
7.
Kaur S, Nieuwenhuijsen MJ, Colvile RN. Fine particulate matter and carbon monoxide exposure concentrations in urban street transport microenvironment. Atmos Environ. 2007;41:4781–810.CrossRef
8.
Sin DD, Wu L, Man SF. The relationship between reduced lung function and cardiovascular mortality: a population-based study and a systematic review of the literature. Chest. 2005;127:1952–9.CrossRefPubMed
9.
Behndig AF, Mudway IS, Brown JL, Stenfors N, Helleday R, Duggan ST, et al. Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans. Eur Respir J. 2006;27:359–65.CrossRefPubMed
10.
Nightingale JA, Maggs R, Cullinan P, Donnelly LE, Rogers DF, Kinnersley R, et al. Airway inflammation after controlled exposure to diesel exhaust particulates. Am J Respir Crit Care Med. 2000;162:161–6.CrossRefPubMed
11.
Nordenhäll C, Pourazar J, Ledin MC, Levin JO, Sandström T, Adelroth E. Diesel exhaust enhances airway responsiveness in asthmatic subjects. Eur Respir J. 2001;17:909–15.CrossRefPubMed
12.
Rudell B, Ledin MC, Hammarström U, Stjernberg N, Lundbäck B, Sandström T. Effects on symptoms and lung function in humans experimentally exposed to diesel exhaust. Occup Environ Med. 1996;53:658–62.CrossRefPubMedPubMedCentral
13.
Salvi S, Blomberg A, Rudell B, Kelly F, Sandström T, Holgate ST, et al. Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. Am J Respir Crit Care Med. 1999;159:702–9.CrossRefPubMed
14.
Stenfors N, Nordenhäll C, Salvi SS, Mudway I, Söderberg M, Blomberg A, et al. Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel. Eur Respir J. 2004;23:82–6.CrossRefPubMed
15.
Xu Y, Barregard L, Nielsen J, Gudmundsson A, Wierzbicka A, Axmon A, et al. Effects of diesel exposure on lung function and inflammation biomarkers from airway and peripheral blood of healthy volunteers in a chamber study. Part Fibre Toxicol. 2013;10:60.CrossRefPubMedPubMedCentral
16.
Larsson BM, Grunewald J, Sköld CM, Lundin A, Sandström T, Eklund A, et al. Limited airway effects in mild asthmatics after exposure to air pollution in a road tunnel. Respir Med. 2010;104:1912–8.CrossRefPubMed
17.
McCreanor J, Cullinan P, Nieuwenhuijsen MJ, Stewart-Evans J, Malliarou E, Jarup L, et al. Respiratory effects of exposure to diesel traffic in persons with asthma. N Engl J Med. 2007;357:2348–58.CrossRefPubMed
18.
Strak M, Janssen NA, Godri KJ, Gosens I, Mudway IS, Cassee FR, et al. Respiratory health effects of airborne particulate matter: the role of particle size, composition, and oxidative potential-the RAPTES project. Environ Health Perspect. 2012;120:1183–9.CrossRefPubMedPubMedCentral
19.
Zuurbier M, Hoek G, Oldenwening M, Meliefste K, van den Hazel P, Brunekreef B. Respiratory effects of commuters’ exposure to air pollution in traffic. Epidemiology. 2011;22:219–27.CrossRefPubMed
20.
Fan ZT, Meng Q, Weisel C, Laumbach R, Ohman-Strickland P, Shalat S, et al. Acute exposure to elevated PM2.5 generated by traffic and cardiopulmonary health effects in healthy older adults. J Expo Sci Environ Epidemiol. 2009;19:525–33.CrossRefPubMed
21.
Jarjour S, Jerrett M, Westerdahl D, de Nazelle A, Hanning C, Daly L, et al. Cyclist route choice, traffic-related air pollution, and lung function: a scripted exposure study. Environ Health. 2013;12:14.CrossRefPubMedPubMedCentral
22.
Meier R, Cascio WE, Ghio AJ, Wild P, Danuser B, Riediker M. Associations of short-term particle and noise exposures with markers of cardiovascular and respiratory health among highway maintenance workers. Environ Health Perspect. 2014;122:726–32.PubMedPubMedCentral
23.
Sarnat JA, Golan R, Greenwald R, Raysoni AU, Kewada P, Winquist A, et al. Exposure to traffic pollution, acute inflammation and autonomic response in a panel of car commuters. Environ Res. 2014;133:66–76.CrossRefPubMedPubMedCentral
24.
Strak M, Boogaard H, Meliefste K, Oldenwening M, Zuurbier M, Brunekreef B, et al. Respiratory health effects of ultrafine and fine particle exposure in cyclists. Occup Environ Med. 2010;67:118–24.CrossRefPubMed
25.
Weichenthal S, Kulka R, Dubeau A, Martin C, Wang D, Dales R. Traffic-related air pollution and acute changes in heart rate variability and respiratory function in urban cyclists. Environ Health Perspect. 2011;119:1373–8.CrossRefPubMedPubMedCentral
26.
Beijing Municipal Bureau of Statistics. Beijing statistical yearbook 2014. Beijing: China Statistics Press; 2014. p. 56–69.
27.
28.
Huang J, Deng F, Wu S, Lu H, Hao Y, Guo X. The impact of short-term exposure to noise and traffic-related air pollution on heart rate variability in young healthy adults. J Expo Sci Environ Epidemiol. 2013;23:559–64.CrossRefPubMed
29.
Zuurbier M, Hoek G, Oldenwening M, Meliefste K, Krop E, van den Hazel P, et al. In-traffic air pollution exposure and CC16, blood coagulation, and inflammation markers in healthy adults. Environ Health Perspect. 2011;119:1384–9.CrossRefPubMedPubMedCentral
30.
Ministry of Environmental Protection of the People’s Republic of China. Exposure factors handbook of Chinese population (adults). Beijing: China Environmental Sciences Press; 2013. p. 12–44.
31.
World Health Organization. Health effects of black carbon. Copenhagen: WHO Regional Office for Europe; 2012. p. 23–33.
32.
Kulkarni N, Pierse N, Rushton L, Grigg J. Carbon in airway macrophages and lung function in children. N Engl J Med. 2006;355:21–30.CrossRefPubMed
Metadaten
Titel
Acute effects on pulmonary function in young healthy adults exposed to traffic-related air pollution in semi-closed transport hub in Beijing
verfasst von
Jing Huang
Furong Deng
Shaowei Wu
Yan Zhao
Masayuki Shima
Bin Guo
Qichen Liu
Xinbiao Guo
Publikationsdatum
01.09.2016
Verlag
Springer Japan
Erschienen in
Environmental Health and Preventive Medicine / Ausgabe 5/2016
Print ISSN: 1342-078X
Elektronische ISSN: 1347-4715
DOI
https://doi.org/10.1007/s12199-016-0531-5

Weitere Artikel der Ausgabe 5/2016

Environmental Health and Preventive Medicine 5/2016 Zur Ausgabe

Regular Article

Association of perfluorinated chemical exposure in utero with maternal and infant thyroid hormone levels in the Sapporo cohort of Hokkaido Study on the Environment and Children’s Health

Regular Article

Bodily pain, social support, depression symptoms and stroke history are independently associated with sleep disturbance among the elderly: a cross-sectional analysis of the Fujiwara-kyo study

Regular Article

Association of beer consumption with arsenic concentration in urine: a result from a cross-sectional study of the general Japanese population

Abstract

Abstracts from Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) vol. 71, no. 2

Regular Article

Serum triglyceride levels in relation to high-density lipoprotein cholesterol (TG-HDL) ratios as an efficient tool to estimate the risk of sleep apnea syndrome in non-overweight Japanese men

Regular Article

Importance of detoxifying enzymes in differentiating fibrotic development between SHRSP5/Dmcr and SHRSP rats