Erschienen in:
28.03.2017 | Editorial Commentary
Acute kidney injury in children with sickle cell disease—compounding a chronic problem
verfasst von:
Cherry Mammen, Mei Lin Bissonnette, Douglas G. Matsell
Erschienen in:
Pediatric Nephrology
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Ausgabe 8/2017
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Abstract
In an article recently published in Pediatric Nephrology, Baddam and colleagues discuss the relatively underreported clinical problem of repeated episodes of acute kidney injury (AKI) in children with sickle cell disease (SCD). Their report is a cautionary note about the importance of repeated kidney injury on the background of underlying chronic kidney injury and its potential implications on long-term kidney outcome. In children and adults with SCD, this includes the effects of repeated vaso-occlusive crises and the management of these painful episodes with non-steroidal anti-inflammatory drugs. Here we review the scope of kidney involvement in SCD in children and discuss the potential short- and long-term consequences of AKI in children with SCD.