Acute Kidney Injury in the Preterm Neonate
- 01.09.2018
- Nephrology - Neonatal AKI (D Askenazi, Section Editor)
Erschienen in:
- Verfasst von
- Adam S. Bauer, MD
- Matthew W. Harer, MD
- Erschienen in
- Current Treatment Options in Pediatrics | Ausgabe 3/2018
Abstract
Purpose of review
Preterm neonates are at increased risk for developing acute kidney injury (AKI). This review describes recent studies evaluating the pathophysiology, diagnosis, prevention, treatment, and outcomes of AKI in neonates born preterm.
Recent findings
Use of the modified neonatal diagnostic criteria from the Kidney Disease: Improving Global Outcomes consortium has helped standardize AKI detection. Novel methods to diagnose AKI, like continuous near infrared spectroscopy, are under investigation. AKI prevention is paramount, and early studies show caffeine results in reduced rates of AKI in preterm neonates. Renal replacement therapy is technically difficult in this population, although newer dialysis equipment created specifically for small neonates are currently being used. Treatment options remain limited with minimal new therapies developed over the past 5 years. Outcome studies of 2–5-year-old NICU graduates have shown that premature neonates with AKI have decreased renal function.
Summary
The increased morbidity and mortality associated with preterm AKI demands continued research into early detection, prevention, and treatment strategies.
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- Titel
- Acute Kidney Injury in the Preterm Neonate
- Verfasst von
-
Adam S. Bauer, MD
Matthew W. Harer, MD
- Publikationsdatum
- 01.09.2018
- Verlag
- Springer International Publishing
- Erschienen in
-
Current Treatment Options in Pediatrics / Ausgabe 3/2018
Elektronische ISSN: 2198-6088 - DOI
- https://doi.org/10.1007/s40746-018-0137-9
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